NLM Eresources

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Subject Terms

  Anatomy
  Animal Testing Alternatives
  Biochemistry
  Biological Assay
  Biology
  Biotechnology
  Books
  Chemical Information
  Chemistry
  Classification
  Clinical Trials
  Computational Biology
  Consumer Health
  Data Specifications
  Devices
  Disaster Information
  Disease & Illness
  Drugs & Supplements
  Education
  Environmental Health & Toxicology
  Genetics & Genomics
  Geographic Information System
  Hazardous Substances
  Health Data Standards
  Health Services Research
  History of Medicine
  Library Services
  Literature
  Medical Imaging
  Medical Informatics
  Molecular Biology
  Newsletter
  Nursing
  Population Groups
  Protein
  Public Health
  Research Reporting Guidelines
  Terminologies
  Virus
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Results    [283]

  AccessGUDID

AccessGUDID contains key device identification information submitted to the FDA about medical devices that have Unique Device Identifiers (UDI).   

Subject Terms: Devices , Health Data Standards , Terminologies
Filters: Database , API
  AccessGUDID API

Provides developers with RESTful API functions for retrieving AccessGUDID data.   

Subject Terms: Devices , Health Data Standards , Terminologies
Filters: Database , API
  AIDSInfo

U.S. Department of Health and Human Services (HHS) resource providing information on HIV/AIDS clinical trials and federally approved HIV treatment and prevention guidelines, information on HIV/AIDS treatment, clinical trials, and other HIV/AIDS-related research information for health care providers, researchers, people affected by HIV/AIDS, and the general public.   

Subject Terms: Consumer Health , Disease & Illness , Drugs & Supplements , Terminologies
Filters: Database , API , App
API: https://aidsinfo.nih.gov/api
  AIDSInfo API

Provides access to the AIDSinfo drug database fact sheets in XML format. The API returns information from both the professional and patient versions of the AIDSinfo drug database fact sheets based on input query strings.   

Subject Terms: Consumer Health , Disease & Illness , Drugs & Supplements , Terminologies
Filters: Database , API , App
  AIDSinfo HIV/AIDS Drug Database

Provides mobile access to information about drugs approved to treat HIV infection, drugs that are used to treat other infections or diseases common to people living with HIV, and also HIV/AIDS-related drugs that are being studied in clinical trials.
Also available for Android   

Subject Terms: Consumer Health , Disease & Illness , Drugs & Supplements , Terminologies
Filters: Database , API , App
  AIDSInfo HIV/AIDS Glossary

The AIDSinfo HIV/AIDS Glossary is a powerful tool that provides mobile access to over 850 pertinent HIV/AIDS glossary terms in both English and Spanish.   

Subject Terms: Consumer Health , Disease & Illness , Drugs & Supplements , Terminologies
Filters: Database , API , App
  AIDSource

Comprehensive listing of HIV/AIDS resources within and outside of NLM.   

Subject Terms: Consumer Health , Disease & Illness
Filters: Reference
  Alternatives to Animal Testing Bibliography (ALTBIB)

Bibliography on alternatives to the use of live vertebrates in biomedical research and testing.   

Subject Terms: Animal Testing Alternatives , Environmental Health & Toxicology
Filters: Reference
  American Indian Health

Health and well-being of American Indians.   

Subject Terms: Population Groups , Public Health
Filters: Database
  Amino Acid Explorer

Explore characteristics of amino acids by comparing their structural and chemical properties, predicting protein sequence changes caused by mutations, viewing common substitutions, and browsing functions of given residues in conserved domains.   

Subject Terms: Biochemistry , Protein
Filters: Tools & Utilities
  Arctic Health

Health and well-being of our planet's northern-most inhabitants.   

Subject Terms: Population Groups , Public Health
Filters: Database
  ASN.1 Format Summary

An International Standards Organization (ISO) data representation format used to achieve interoperability between platforms.   

Subject Terms: Data Specifications
Filters: Dataset
  Assembly Database

A database provides information on the structure of assembled genomes, assembly names and other meta-data, statistical reports, and links to genomic sequence data.   

Subject Terms: Genetics & Genomics
Filters: Database
  Batch Entrez

Retrieve records from Entrez databases by uploading a file of GI or accession numbers from the Nucleotide or Protein databases, or a file of unique identifiers from other Entrez databases. Save results in various formats.   

Subject Terms: Computational Biology
Filters: Tools & Utilities
  BioProject

A collection of genomics, functional genomics, and genetics studies and links to their resulting datasets. This resource describes project scope, material, and objectives and provides a mechanism to retrieve datasets that are often difficult to find due to inconsistent annotation, multiple independent submissions, and the varied nature of diverse data types which are often stored in different databases.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  BioSample

Database containing descriptions of biological source materials used in experimental assays.   

Subject Terms: Biological Assay
Filters: Database
  BioSystems

Database grouping biomedical literature, small molecules, and sequence data in terms of biological relationships.   

Subject Terms: Computational Biology
Filters: Database
  Biotechnology Information

Molecular biology, computational biology and related software tools.   

Subject Terms: Biotechnology , Computational Biology
Filters: Tools & Utilities
  BLAST (Basic Local Alignment Search Tool)

Find regions of local similarity between sequences and compare nucleotide or protein sequences to sequence databases and calculate the statistical significance of matches.   

Subject Terms: Biotechnology , Computational Biology , Protein
Filters: Database , Tools & Utilities , Training & Instructional Materials , API
  BLAST (Basic Local Alignment Search Tool) Tutorials and Guides

Includes links for a selection guide for BLAST algorithms, descriptions of BLAST output formats, explanations of the parameters for stand-alone BLAST, directions for setting up stand-alone BLAST on local machines and using the BLAST URL API.   

Subject Terms: Biotechnology , Computational Biology , Protein
Filters: Database , Tools & Utilities , Training & Instructional Materials , API
  BLAST (Stand-alone)

Suite of BLAST tools that utilize the NCBI C++ Toolkit.   

Subject Terms: Biotechnology , Computational Biology , Protein
Filters: Database , Tools & Utilities , Training & Instructional Materials , API
  BLAST API

API for Basic Local Alignment Search Tool (BLAST) services which find regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.   

Subject Terms: Biotechnology , Computational Biology , Protein
Filters: Database , Tools & Utilities , Training & Instructional Materials , API
  BLAST Databases

Sequence databases for use with the stand-alone BLAST programs. The files in this directory are pre-formatted databases that are ready to use with BLAST.   

Subject Terms: Biotechnology , Computational Biology , Protein
Filters: Database , Tools & Utilities , Training & Instructional Materials , API
  Bookshelf

A collection of online biomedical books whose full text can be searched through the Entrez system.   

Subject Terms: Books
Filters: Database , Reference
  Carcinogenic Potency Database (CPDB)

Standardized analyses of the results of 6,540 chronic, long-term animal cancer tests (1980-2011).   

Subject Terms: Disease & Illness
Filters: Database
  CDTree

A stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies, and also allows users to create their own.   

Subject Terms: Protein
Filters: Database , Tools & Utilities
  Chemical Carcinogenesis Research Information System (CCRIS)

Carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition test results on chemicals.   

Subject Terms: Disease & Illness , Environmental Health & Toxicology
Filters: Database , Dataset
  Chemical Hazards Emergency Medical Management (CHEMM)

Enables first responders and other healthcare providers and planners to plan for, respond to, recover from, and mitigate the effects of mass-casualty incidents involving accidental or terrorist chemical releases.   

Subject Terms: Chemical Information , Disaster Information , Hazardous Substances
Filters: Database
  Chemical Identification Plus Database (ChemIDplus)

Online dictionary of chemicals, including names, synonyms, and chemical structures.   

Subject Terms: Chemistry
Filters: Database , Dataset
  ChemSpell Web Service API

The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up.   

Subject Terms: Chemistry , Terminologies
Filters: Database , API
  Citing Medicine

Provides guidance for citing published and unpublished material, ranging from print books and journal articles to blogs, wikis and preprint materials.   

Subject Terms: Books
Filters: Reference
  Clinical Alerts

Messages provided to expedite the release of findings from the NIH-funded clinical trials where such release could significantly affect morbidity and mortality.   

Subject Terms: Clinical Trials
Filters: Reference
  ClinicalTrials.gov

Patient studies for drugs and treatment.   

Subject Terms: Clinical Trials
Filters: Database , API
  ClinicalTrials.gov API

Method for creating links to ClinicalTrials.gov or downloading data in XML format. Information includes a trial's purpose, who may participate, locations, and contact information for details about trials conducted in the U.S. and around the world.   

Subject Terms: Clinical Trials
Filters: Database , API
  ClinVar

A resource under development to provide a public, tracked record of reported relationships among human variation and observed health status.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  Cn3D

A stand-alone application for viewing 3-dimensional structures from NCBI Entrez retrieval service. Runs on Windows, Macintosh, and UNIX and can be configured to receive data from most popular Web browsers.   

Subject Terms: Molecular Biology
Filters: Tools & Utilities
  COBALT

COBALT is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and sequence similarity, using RPS-BLAST, BLASTP, and PHI-BLAST.   

Subject Terms: Protein
Filters: Tools & Utilities
  Coffee Break

A collection of short stories and interactive tutorials about recent biomedical discoveries.   

Subject Terms: Books
Filters: Reference , Training & Instructional Materials
  Community Health Maps

Low cost and easy-to-use mapping and mobile communication tools.   

Subject Terms: Consumer Health , Geographic Information System , Public Health
Filters: Tools & Utilities , Training & Instructional Materials
  Comparative Toxicogenomics Database (CTD)

Contains manually curated data describing cross-species chemical-gene/protein interactions and chemical-and gene-disease relationships.   

Subject Terms: Environmental Health & Toxicology , Genetics & Genomics , Protein
Filters: Database
  Computational Resources from NCBI Structure Group

A centralized resource covering databases and tools to help in the study of macromolecular structures, conserved domains and protein classification, small molecules and their biological activity, biological pathways, and systems.   

Subject Terms: Computational Biology
Filters: Reference , Tools & Utilities
  Consensus CDS (CCDS)

A collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality.   

Subject Terms: Genetics & Genomics , Protein
Filters: Database , Dataset
  Conserved Domain Search Service (CD Search)

Identifies the conserved domains present in a protein sequence. CD-Search uses RPS-BLAST (Reverse Position-Specific BLAST) to compare a query sequence against position-specific score matrices that have been prepared from conserved domain alignments present in the Conserved Domain Database (CDD).   

Subject Terms: Computational Biology
Filters: Tools & Utilities
  Conserved Domains Database (CDD)

Collection of sequence alignments and profiles representing protein domains conserved in molecular evolution.   

Subject Terms: Computational Biology , Protein
Filters: Database , Dataset
  DailyMed

DailyMed contains drug information in SPL (Structured Product Label) format for US marketed drugs.   

Subject Terms: Drugs & Supplements
Filters: Database , Dataset , Tools & Utilities , API
  DailyMed API

Provides high quality information about marketed drugs, including FDA labels (package inserts). Currently DailyMed publishes “RESTful” API for querying DailyMed database.   

Subject Terms: Drugs & Supplements
Filters: Database , Dataset , Tools & Utilities , API
  Data Discovery at NLM

A platform to provide access to datasets from selected NLM resources. Users can explore, filter, visualize, and export data in a variety of formats, including Excel, JSON, XML, as well as access and build with these datasets via API.   

Subject Terms:
Filters: Database , Dataset , Tools & Utilities , API
  Database of Genomic Structural Variation (dbVar)

The dbVar database archives information associated with large scale genomic variation, including large insertions, deletions, translocations and inversions. dbVar also stores associations of defined variants with phenotype information.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Database of Genotype and Phenotype (dbGaP)

Data from genome wide association (GWA) studies, which aim to establish associations between genotype and phenotype information to elucidate the link between genes and disease.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Database of Single Nucleotide Polymorphisms (dbSNP)

Includes single nucleotide polymorphisms, microsatellites, and small-scale insertions and deletions. Contains population-specific frequency and genotype data, as well as mapping information for both neutral polymorphisms and clinical mutations.   

Subject Terms: Genetics & Genomics
Filters: Database , Tools & Utilities
  Developmental and Reproductive Toxicology Database (DART)

References to the teratology, developmental, and reproductive toxicology literature.   

Subject Terms: Environmental Health & Toxicology
Filters: Database
  Dietary Supplement Label Database

A free source of information, created via a collaboration of the NIH Office of Dietary Supplements with the National Library of Medicine, from the labels of dietary supplements marketed and sold in the United States.   

Subject Terms: Drugs & Supplements
Filters: Database , Training & Instructional Materials
  Digital Collections

NLM's online repository of digitized and born digital resources including books, still images, videos, and maps.   

Subject Terms: Books , Library Services , History of Medicine
Filters: Images , Multilanguage , Reference , API
  Digital Collections Web Service API

Provides access to metadata and full-text OCR of all resources in the Digital Collections repository in XML format. Developers can use the Web service to incorporate NLM historical monographs, films and other resources into their own applications.   

Subject Terms: Books , Library Services , History of Medicine
Filters: Images , Multilanguage , Reference , API
  Directory of History of Medicine Collections

Research, reference and interlibrary loan services.   

Subject Terms: Library Services , History of Medicine
Filters: Reference
  Disaster Information

The Disaster Information Management Research Center provides health information resource and informatics research related to disasters of natural, accidental, or deliberate origin.   

Subject Terms: Disaster Information , Environmental Health & Toxicology , Hazardous Substances
Filters: Reference , Tools & Utilities
  Disaster Lit: Resource Guide for Disaster Medicine and Public Health

Guide to freely available online disaster medicine and public health literature and related information.   

Subject Terms: Disaster Information , Environmental Health & Toxicology , Hazardous Substances , Literature , Public Health
Filters: Database
  DOCLINE

NLM’s automated interlibrary loan (ILL) request routing and referral system. The web-based system provides efficient resource sharing of biomedical literature via ILL among libraries in the National Network of Libraries of Medicine (NNLM) and beyond.   

Subject Terms: Library Services , Literature
Filters: Database
  Download MEDLINE/PubMed Data

NLM distributes MEDLINE/PubMed data in XML to individuals and organizations for use in accordance with NLM Terms and Conditions.   

Subject Terms: Literature
Filters: Dataset
  Drug Information Portal

Information for over 55,000 drugs. Names, usage, and structures are displayed, as well as search links to key NLM and government sites.   

Subject Terms: Drugs & Supplements
Filters: Database
  Drug Information Portal Mobile

A mobile interface to information for over 55,000 drugs. Names, usage, and structures are displayed, as well as search links to key NLM and government sites, using their mobile version when available.   

Subject Terms: Drugs & Supplements
Filters: Database , App
  Drug-Drug Interactions API

Provides developers with functions for identifying potential drug-drug interactions for RxNorm drugs and checking interactions in a list of drugs. Two Drug-drug interactions APIs (SOAP/WSDL and RESTful) are available for retrieving drug-drug interaction information.   

Subject Terms: Drugs & Supplements
Filters: API
  Ebot

A tool that allows users to construct an E-utility analysis pipeline using an online form, and then generates a Perl script to execute the pipeline.   

Subject Terms: Computational Biology , Molecular Biology
Filters: Tools & Utilities
  Entrez

Search the biomedical databases of the Entrez Molecular Biology System.   

Subject Terms: Computational Biology
Filters: Database
  Entrez Programming Utilities

Tools that provide access to data within the NCBI Entrez system outside of the regular Web query interface. Entrez tasks are automated within applications and each specialized retrieval task can be used simply by writing a specially formatted URL.   

Subject Terms: Computational Biology
Filters: API
  Environmental Health and Toxicology Information

Portal to numerous NLM databases and resource in environmental health and toxicology.   

Subject Terms: Chemical Information , Environmental Health & Toxicology , Hazardous Substances , Public Health
Filters: Database
  Environmental Health Student Portal

Environmental Health education resources for middle school students and their teachers.   

Subject Terms: Environmental Health & Toxicology
Filters: Dataset , Training & Instructional Materials
  FASTA BLAST Databases

Sequence databases in FASTA format for use with the stand-alone BLAST programs. These databases must be formatted using formatdb before they can be used with BLAST.   

Subject Terms: Computational Biology
Filters: Dataset
  FDA Notices of Judgment Collection

Archive of digitized court case summaries published between 1906-1965 for foods, drugs, cosmetics, and medical devices seized by the FDA under the 1906 Pure Food and Drug Act. Gateway to the 2,400+ box collection of prosecution’s evidence files. The Web Service API provides access to metadata and full-text OCR of all resources in the repository in XML format.   

Subject Terms: History of Medicine
Filters: Database , API
API: https://fdanj.nlm.nih.gov/web_service
  GenBank

NIH Genetic sequence database, an annotated collection of all publicly available DNA sequences.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  GenBank: BankIt

A Web-based sequence submission tool for one or a few submissions to the GenBank database, designed to make the submission process quick and easy.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  GenBank: Barcode

Tool for submission to the GenBank database of Barcode short nucleotide sequences from a standard genetic locus for use in species identification.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  GenBank: Sequin

A stand-alone software tool developed by the NCBI for submitting and updating entries to public sequence databases (GenBank, EMBL, or DDBJ). For simple submission, use the online submission tool BankIt instead.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  GenBank: tbl2asn

A command-line program that automates the creation of sequence records for submission to GenBank using many of the same functions as Sequin. It is used primarily for submission of complete genomes and large batches of sequences.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Gene

Database of gene-specific information. Each record represents a single gene from a given organism and can include, as available, nomenclature, map, sequence, expression, structure, functional, and homology data.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  Gene Expression Omnibus (GEO)

GEO is a public functional genomics data repository supporting MIAME-compliant data submissions. There are also tools provided to help users query and download experiments and curated gene expression profiles.   

Subject Terms: Genetics & Genomics
Filters: Database
  Gene Expression Omnibus (GEO) BLAST

Tool for aligning a query sequence (nucleotide or protein) to GenBank sequences included on microarray or SAGE platforms in the GEO database.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Gene Expression Omnibus (GEO) Database

A public functional genomics data repository supporting MIAME-compliant data submissions. Array- and sequence-based data are accepted and tools are provided to help users query and download experiments and curated gene expression profiles.   

Subject Terms: Genetics & Genomics
Filters: Database
  Gene Expression Omnibus (GEO) Datasets

A component of the Gene Expression Omnibus (GEO) repository that contains submitter-supplied records (known as "GEO Series"), which summarize individual experiments, plus GEO DataSets that are assembled by GEO staff.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Gene Expression Omnibus (GEO) Profiles

Individual gene expression and molecular abundance profiles assembled from the Gene Expression Omnibus (GEO) repository. A Profile consists of the expression measurements for an individual gene across all Samples in a DataSet.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Gene Expression Omnibus (GEO) Web Deposit

Submit expression data, such as microarray, SAGE or mass spectrometry datasets to the NCBI Gene Expression Omnibus (GEO) database.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  GENE-TOX (Genetic Toxicology DataBank)

Mutagenicity test data on chemicals based on peer review of the scientific literature.   

Subject Terms: Environmental Health & Toxicology , Genetics & Genomics
Filters: Database , Dataset
  GeneED

Explore topics such as Cell Biology, DNA, Genes, Chromosomes, Heredity/Inheritance Patterns, Epigenetics/Inheritance and the Environment, Genetic Conditions, Evolution, Biostatistics, Biotechnology, DNA Forensics, and Top Issues in Genetics.   

Subject Terms: Genetics & Genomics
Filters: Dataset , Training & Instructional Materials
  GeneRIF

GeneRIF provides a simple mechanism to allow scientists to add to the functional annotation of genes in the Gene database.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Tools & Utilities
  Genes and Disease

Summary information for more than 80 genetic disorders with discussions of the underlying mutation(s) and clinical features, as well as links to related databases and organizations.   

Subject Terms: Genetics & Genomics
Filters: Database
  Genetic Codes

Displays the genetic codes for organisms in the Taxonomy database in tables and on a taxonomic tree.   

Subject Terms: Genetics & Genomics
Filters: Database , Tools & Utilities
  Genetic Relationship and Fingerprinting (GRAF)

Genetic Relationship and Fingerprinting (GRAF) is a rapid statistical method to detect duplicates and closely related samples in large genomic datasets to be used as a quality assurance tool in dbGaP data processing. For more information, see this abstract in PubMed.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Tools & Utilities
  Genetic Testing Registry (GTR) [NOTE: replaces GeneTests]

A free, centralized voluntary registry of comprehensive genetic test information covering clinical and research tests for Mendelian disorders and drug responses including multigenic, array-based, biochemical, cytogenetic, and molecular tests.   

Subject Terms: Genetics & Genomics
Filters: Database , Tools & Utilities
  Genetics Home Reference

Genetic conditions and the genes or chromosomes responsible.   

Subject Terms: Consumer Health , Disease & Illness , Education , Genetics & Genomics
Filters: Reference
  Genetics Home Reference API

Method for creating links or downloading Genetics Home Reference data in XML format. This service contains consumer information about genetic conditions, genes, and chromosome related to those conditions.   

Subject Terms: Consumer Health , Disease & Illness , Education , Genetics & Genomics
Filters: Dataset , Reference , API
API: https://ghr.nlm.nih.gov/about/data-files-api
  Genome

Sequence and map data from the whole genomes of organisms. The genomes represent both completely sequenced organisms and those for which sequencing is in progress.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  Genome BLAST

This tool compares nucleotide or protein sequences to genomic sequence databases and calculates the statistical significance of matches using the Basic Local Alignment Search Tool (BLAST) algorithm.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Tools & Utilities
  Genome Data Viewer (GDV)

GDV is a genome browser supporting the exploration and analysis of more than 500 eukaryotic RefSeq genome assemblies. GDV replaced the Map Viewer.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Genome Decoration Page

An online tool that assists in the production of journal quality figures of annotations on an ideogram or sequence representation of an assembly.   

Subject Terms: Genetics & Genomics
Filters: Reference , Tools & Utilities
  Genome Mapping Data

Contains directories for each genome that include available mapping data for current and previous builds of that genome.   

Subject Terms: Genetics & Genomics
Filters: Dataset , Reference
  Genome Reference Consortium (GRC)

Maintains responsibility for the human and mouse reference genomes and works to correct misrepresented loci and to close remaining assembly gaps. Also seeks to provide alternate assemblies for complex or structurally variant genomic loci.   

Subject Terms: Genetics & Genomics
Filters: Database
  Genome Remapping Service

NCBI Remap tool allows users to project annotation data from one assembly to another through a base by base analysis. Options are provided to adjust the stringency of remapping, and summary results are displayed on the page.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Genome Workbench

An integrated application for viewing and analyzing sequence data. With Genome Workbench, you can view data in publically available sequence databases at NCBI, and mix these data with your own data.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Genomic Basic Local Alignment Search Tool (BLAST)

This tool compares nucleotide or protein sequences to genomic sequence databases and calculates the statistical significance of matches.   

Subject Terms: Genetics & Genomics , Protein
Filters: Tools & Utilities
  GenPept

The protein sequences corresponding to the translations of coding sequences (CDS) in GenBank are collected for each GenBank release..Please see the README file in the directory for more information.   

Subject Terms: Genetics & Genomics , Protein
Filters: Dataset
  Haz-Map

Links jobs and hazardous tasks with occupational diseases and their symptoms.   

Subject Terms: Environmental Health & Toxicology , Hazardous Substances
Filters: Database , App
  Hazardous Substances Data Bank (HSDB)

Comprehensive, peer-reviewed toxicology data for about 5,000 chemicals.   

Subject Terms: Environmental Health & Toxicology , Hazardous Substances
Filters: Database
  Health Data Standards and Privacy

NLM participation in activities relating to nationwide implementation of an interoperable health information technology infrastructure to improve the quality and efficiency of health care.   

Subject Terms: Health Data Standards , Medical Informatics , Terminologies
Filters: Dataset , API
  Health Service Research (HSR) PubMed Queries

Preformulated specialized PubMed searches on healthcare quality and costs, based on search filtered designed by Haynes RB.   

Subject Terms: Health Services Research
Filters: Database , Reference
  Health Services and Sciences Research Resources (HSRR)

Research datasets and instruments/indices.   

Subject Terms: Health Services Research
Filters: Database
  Health Services Research & Health Care Technology

Resources relating to access, cost, and quality issues in healthcare.   

Subject Terms: Health Services Research
Filters: Database , Training & Instructional Materials
  Health Services Research & Public Health Information Programs

Provides access to the resources of the National Information Center on Health Services Research and Health Care Technology, including databases, web portals, webinars, preformulated PubMed searches, tutorials, and e-texts.   

Subject Terms: Health Data Standards , Health Services Research , Public Health
Filters: Database , Reference
  Health Services Research Information Central

A health services research information portal.   

Subject Terms: Health Services Research
Filters: Reference
  Health Services Research Projects (HSRProj)

Ongoing grants and contracts in health services research.   

Subject Terms: Health Services Research
Filters: Database
  HealthReach

Multilingual and multicultural health information for those working with or providing care to individuals with limited English proficiency.   

Subject Terms: Population Groups , Public Health
Filters: Database , Dataset , Multilanguage
  Healthy People 2020 Structured Evidence Queries

One-click PubMed search strategies related to Healthy People 2020 public health objectives.   

Subject Terms: Health Services Research , Public Health
Filters: Reference
  History of Medicine

Exhibitions, historical scholarship, and images in medicine.   

Subject Terms: History of Medicine
Filters: Images , Reference
  History of Medicine Finding Aids

HMD Finding Aids is the central access point for electronic finding aids provided by the Archives and Modern Manuscripts and Prints and Photographs collections. XML is available via this list: http://oculus.nlm.nih.gov/f/findaid/harvest/list.html.   

Subject Terms: History of Medicine
Filters: Database , Images , Reference
  HIV-1, Human Protein Interaction Database

Information about known interactions of HIV-1 proteins with proteins from human hosts. It provides annotated bibliographies of published reports of protein interactions, with links to the corresponding PubMed records and sequence data.   

Subject Terms: Virus
Filters: Database
  HomoloGene

System for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes.   

Subject Terms: Genetics & Genomics
Filters: Dataset
  Household Products Database

Health and safety information on household products.   

Subject Terms: Environmental Health & Toxicology
Filters: Database
  IgBLAST

A tool to facilitate the analysis of immunoglobulin and T cell receptor variable domain sequences. For more information, see this abstract in PubMed.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Tools & Utilities
  Images from the History of Medicine

Images from the History of Medicine (IHM) in NLM Digital Collections provides online access to images from the historical collections of the U.S. National Library of Medicine. IHM includes image files of a wide variety of visual media including fine art, photographs, engravings, and posters that illustrate the social and historical aspects of medicine dating from the 15th to 21st century.   

Subject Terms: History of Medicine
Filters: Database , Images
  IndexCat

User interface that provides access to the digitized version of the printed Index-Catalogue of the Library of the Surgeon General’s Office; eTK for medieval Latin texts; and eVK2 for medieval English texts. XML data are available for download.   

Subject Terms: Library Services , History of Medicine
Filters: Database , Dataset
  Influenza Virus Resource

Provides researchers with a growing collection of virus sequences essential to the identification of the genetic determinants of influenza pathogenicity.   

Subject Terms: Virus
Filters: Database , Dataset
  Integrated Risk Information System (IRIS)

Hazard identification and dose-response assessments on chemicals.   

Subject Terms: Environmental Health & Toxicology , Hazardous Substances
Filters: Database
  Interlibrary Loan

Interlibrary loan services are available only to libraries.   

Subject Terms: Library Services , Literature
Filters: Reference
  International Toxicity Estimates for Risk (ITER)

Risk information on chemicals from several authoritative organizations worldwide.   

Subject Terms: Environmental Health & Toxicology , Hazardous Substances
Filters: Database
  Journals in NCBI Databases

Look up journals cited in NCBI databases, including PubMed.   

Subject Terms: Library Services , Literature
Filters: Database
  LactMed (Drugs and Lactation Database)

Find information about maternal and infant drug levels, possible effects on lactation and on breastfed infants, and alternative drugs to consider.   

Subject Terms: Consumer Health , Environmental Health & Toxicology , Population Groups
Filters: Database
  LactMed Mobile App for iPhone/iPod Touch/Android Devices

Find information about maternal and infant drug levels, possible effects on lactation and on breastfed infants, and alternative drugs to consider. Mobile version   

Subject Terms: Environmental Health & Toxicology , Population Groups
Filters: Database , App
  Learning Resources API

The REST API provides identifiers to allow the user to search by title, subject, and description. This returns the information in JSON allowing Web pages to parse and display the information for end users.   

Subject Terms: Education
Filters: Database , Training & Instructional Materials , API
  Learning Resources Database

The Learning Resources Database collects educational materials created by NLM. These materials include videos, tutorials, webinars, and other resources that provide user education on NLM products and services.   

Subject Terms: Education
Filters: Database , Training & Instructional Materials , API
  LinkOut

Third parties can link directly from PubMed and other Entrez database records to relevant Web-accessible resources beyond the Entrez system. Includes full-text publications, biological databases, consumer health information and research tools.   

Subject Terms: Library Services , Literature
Filters: Tools & Utilities
  List of Serials Indexed for Online Users

Bibliographic information for serials indexed in MEDLINE (available in XML).   

Subject Terms: Library Services , Literature
Filters: Database , Dataset
  LiverTox

Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements.   

Subject Terms: Environmental Health & Toxicology
Filters: Database
  Loansome Doc

A document delivery request system provided by NLM which allows individuals to order articles retrieved in PubMed searches from DOCLINE libraries with whom they have registered.   

Subject Terms: Library Services , Literature
Filters: Dataset
  LocatorPlus

A MARC-based catalog of books, journals, audiovisuals, electronic resources, and other materials including holdings and availability.   

Subject Terms: Books , Library Services , Literature
Filters: Database , Multilanguage , Tools & Utilities
  LOINC Mapto API

The LOINC Mapto API is a web service for accessing the mappings of LOINC concepts.   

Subject Terms: Health Data Standards , Terminologies
Filters:
  Martin Cummings and the NLM

An online edition of XML-encoded speeches, articles, and Congressional Appropriations testimonies by former NLM director Martin M. Cummings, based on the collection of his papers in HMD’s Modern Manuscripts collection.   

Subject Terms: History of Medicine
Filters: Database , Reference
  MedGen

A portal to information about medical genetics. MedGen includes term lists from multiple sources and organizes them into concept groupings and hierarchies.   

Subject Terms: Genetics & Genomics
Filters: Database
  Medical Subject Headings (MeSH)

Controlled vocabulary thesaurus and MeSH Browser.   

Subject Terms: Terminologies
Filters: Database
  Medical Text Indexer (MTI)

A system for producing indexing recommendations to assist in the indexing process at NLM. Currently provides indexing recommendations to more than 100 journals based on the NLM Medical Subject Headings (MeSH) vocabulary.   

Subject Terms: Medical Informatics , Terminologies
Filters: Tools & Utilities
  MEDLINE/PubMed

References including abstracts to articles in thousands of biomedical journals.   

Subject Terms: Books , Literature
Filters: Database
  MEDLINE/PubMed Baseline Repository (MBR)

Resources related to the annual baseline files. Includes a query tool for Web-based searching for use by NLM registered MEDLINE/PubMed licensees.   

Subject Terms: Literature
Filters: Database , Dataset
  MedlinePlus

Health information for patients, families and health care providers. Also in Spanish.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus Connect

A free service that allows electronic health record (EHR) systems to link to relevant and authoritative health information from MedlinePlus.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus Connect API

Web application that responds to requests with an on-demand, formatted MedlinePlus Connect Web Service in which a patient portal or EHR selects which MedlinePlus links and information to provide from within the system.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus en Español

Health information for patients, families and health care providers in Spanish.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus English Widgets and Buttons

MedlinePlus makes trusted, reliable health information easily accessible in a variety of formats, including widgets and buttons. This resource allows the user to embed widgets and buttons on a Web site.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus Health Topic XML Files

The MedlinePlus Health Topic XML files contain records for all English and Spanish health topics. Each health topic record includes data elements associated with that topic and are available for download.   

Subject Terms: Consumer Health , Public Health
Filters: Dataset , Multilanguage
  MedlinePlus Health Topics API

Provides access to health topic data in XML format. The service accepts keyword searches as requests and returns links to relevant English-language health topics in ranked order.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedlinePlus Spanish Widgets and Buttons

MedlinePlus makes trusted, reliable health information easily accessible in a variety of formats, including widgets and buttons. This resource allows the user to embed widgets and buttons on a Web site in Spanish.   

Subject Terms: Consumer Health , Public Health
Filters: Database , Multilanguage , Tools & Utilities , API , App
  MedPix

MedPix is a database of patient cases integrating images and textual information. The content material is organized by disease location (organ system), pathology category, patient profiles, and by image classification and caption.   

Subject Terms: Education , Medical Imaging
Filters: Database , Images , Training & Instructional Materials
  MeSH Browser

Medical Subject Heading search tool.   

Subject Terms: Terminologies
Filters: Database
  MeSH Database

NLM controlled vocabulary used for indexing articles for MEDLINE/PubMed. MeSH terminology provides a consistent way to retrieve information that may use different wording for the same concepts.   

Subject Terms: Terminologies
Filters: Database
  MeSH on Demand

MeSH on Demand identifies MeSH Terms in your text using the NLM Medical Text Indexer (MTI) program. After processing, MeSH on Demand returns a list of MeSH Terms relevant to your text as well as a list of related articles from PubMed.   

Subject Terms: Literature , Terminologies
Filters: Tools & Utilities
  MeSH RDF

Medical Subject Headings(MeSH) linked data. Includes a SPARQL endpoint, RESTful interface and bulk download of MeSH RDF data.   

Subject Terms: Health Data Standards , Terminologies
Filters: Database , Dataset , Reference , API
  MetaMap

Highly configurable program to map biomedical text to the UMLS Metathesaurus or, equivalently, to discover Metathesaurus concepts referred to in text.   

Subject Terms: Terminologies
Filters: Dataset
  MetaMap API

The MetaMap Java API and the MetaMap UIMA Annotator allow users to access MetaMap directly through their Java-based application(s).   

Subject Terms: Terminologies
Filters: API
  Molecular Biology

Molecular biology, computational biology and related software tools.   

Subject Terms: Molecular Biology
Filters: Dataset
  Multiple Sequence Alignment (MSA) Viewer

An interactive Web application that enables users to visualize multiple alignments created by database search results or other software applications. The MSA Viewer allows users to upload an alignment and set a master sequence and to explore the data using features such as zooming and changing of coloration.   

Subject Terms: Protein
Filters: Database , Tools & Utilities , API
  National Drug File - Reference Terminology API

Provides clinical information about medications, including therapeutic intent, mechanism of action, and physiologic effect. Two NDF-RT APIs (SOAP/WSDL and RESTful) are available for retrieving NDF-RT data.   

Subject Terms: Drugs & Supplements , Terminologies
Filters: API
  NCBI C++ Toolkit Manual

A comprehensive manual on the NCBI C++ toolkit, including its design and development framework, a C++ library reference, software examples and demos, FAQs and release notes. It is searchable online and can be downloaded as a series of PDF documents.   

Subject Terms: Computational Biology
Filters: Database
  NCBI Data Specifications

Specifications for NCBI data in ASN.1 or DTD format. The “NCBI_data_conversion.html” links to the conversion tool.   

Subject Terms: Computational Biology
Filters: Dataset
  NCBI Glossary

Part of the NCBI Handbook, this glossary contains descriptions of NCBI tools and acronyms, bioinformatics terms and data representation formats.   

Subject Terms: Computational Biology , Terminologies
Filters: Database , Reference
  NCBI Handbook

An extensive collection of articles about NCBI databases and software.   

Subject Terms: Computational Biology
Filters: Database , Reference
  NCBI Help Manual

Accessed through the NCBI Bookshelf, the Help Manual contains documentation for many NCBI resources, including PubMed, PubMed Central, the Entrez system, Gene, SNP and LinkOut. All chapters can be downloaded in PDF format.   

Subject Terms: Computational Biology
Filters: Database , Reference
  NCBI Insights

The Blog provides perspective on NCBI resources, introduces new resources, explains how to perform specific tasks, and explores current topics in science, and how to find relevant NCBI resources for further exploration.   

Subject Terms: Computational Biology
Filters: Tools & Utilities
  NCBI Learn

Links to tutorials and training materials, including PowerPoint slides and print handouts.   

Subject Terms: Computational Biology
Filters: Database , Training & Instructional Materials
  NCBI Pathogen Detection Project

A project involving the collection and analysis of bacterial pathogen genomic sequences originating in food, environmental sources, and patients. It quickly clusters and identifies related sequences to uncover potential food contamination sources, helping public health scientists investigate foodborne disease outbreaks.   

Subject Terms: Public Health
Filters: Database , Tools & Utilities
  NCBI Website Search

A database of static NCBI Web pages, documentation, and online tools. Includes specialized online sequence analysis tools, back issues of newsletters, legacy resource description pages, sample code, and other miscellaneous resources.   

Subject Terms: Computational Biology
Filters: Database
  NICHSR ONESearch

A search platform enables users to access all of NICHSR (National Information Center on Health Services Research and Health Care Technology) databases and Web portals (HSRProj, HSRR, HSRIC and PHPartners) for health services research and public health.   

Subject Terms: Health Services Research , Public Health
Filters: Database
  NIH Common Data Elements (CDE) Repository

The NIH Common Data Elements (CDE) Repository has been designed to provide access to structured human and machine-readable definitions of data elements that have been recommended or required by NIH Institutes and Centers and other organizations for use in research and for other purposes.   

Subject Terms: Health Data Standards , Medical Informatics , Terminologies
Filters: Database , API
API: https://cde.nlm.nih.gov/api
  NIH Manuscript Submission System (NIHMS)

The NIH Public Access Policy requests that researchers funded by NIH submit their final, peer-reviewed manuscripts, which have been accepted for publication, to PubMed Central.   

Subject Terms: Literature
Filters: Tools & Utilities
  NIH Public Access

The NIH Public Access Policy ensures that the public has access to the published results of NIH-funded research. The NIH Manuscript Submission System is a mechanism for authors to deposit their NIH-funded manuscripts.   

Subject Terms: Literature
Filters: Database , Reference
  NLM Catalog

An NLMXML-based catalog of books, journals, audiovisuals, electronic resources, and other materials with links to holdings and availability.   

Subject Terms: Books , Library Services , Literature
Filters: Database , Multilanguage , Tools & Utilities
  NLM Classification

A classification scheme for the arrangement of medical library collections.   

Subject Terms: Classification , Library Services
Filters: Database , Tools & Utilities
  NLM DTDs

A Suite of tag sets for authoring and archiving journal articles. Provides a set of XML schema modules that define elements and attributes for describing the textual and graphical content of journal articles as well as some non-article materials.   

Subject Terms: Data Specifications
Filters: Tools & Utilities
  NLM Gateway

Search multiple retrieval systems.   

Subject Terms: Literature
Filters: Database
  NLM Native Voices Mobile App for iPad

This is the official app for the popular Native Voices: Native Concepts of Health and Illness exhibition at the National Library of Medicine.   

Subject Terms: Population Groups , Public Health
Filters: App
  NLM Technical Bulletin

Web-based newsletter for NLM online searchers.   

Subject Terms: Newsletter
Filters: Dataset , Reference
  Nucleotide

Contains nucleotide sequence data from organisms. Includes data from a number of sources databases such as GenBank, RefSeq, TPA, and PDB.   

Subject Terms: Biochemistry
Filters: Database , Dataset , Tools & Utilities
  Nursing Resources for Standards and Interoperability

A nursing terminologies resource for systems development. Describes the role of SNOMED CT and Laboratory Observation Identifiers Names and Codes (LOINC) in implementing Meaningful Use in the U.S., specifically for the nursing and care domain.   

Subject Terms: Health Data Standards , Nursing , Population Groups , Terminologies
Filters: Reference
  OLDMEDLINE Data

References to biomedical journal articles 1947 through 1965.   

Subject Terms: Literature
Filters: Database
  OMIM (Online Mendelian Inheritance in Man)

Comprehensive, authoritative, and timely compendium of human genes and genetic phenotypes.   

Subject Terms: Genetics & Genomics
Filters: Database , API
  Online Exhibitions and Digital Projects

Enhancing the public and scholarly awareness and appreciation of National Library of Medicine collections.   

Subject Terms: History of Medicine , Population Groups , Public Health
Filters: Reference
  Online Oral Histories

History of Medicine Division's XML-encoded online oral histories provide access to a wealth of digitized transcripts, and audio when available.   

Subject Terms: History of Medicine
Filters: Database , Dataset , Reference
  Open Reading Frame Finder (ORF Finder)

A graphical analysis tool that finds all open reading frames in a user's sequence or in a sequence already in the database.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Open-i

Open-i service provides search and retrieval of abstracts and images (including charts, graphs, clinical images, etc.) from the open source literature, and biomedical image collections. Searching may be done by text queries as well as by query images.   

Subject Terms: Literature
Filters: Database , Images
  OSIRIS

A public domain quality assurance software package that facilitates the assessment of multiplex short tandem repeat (STR) DNA profiles based on laboratory-specific protocols.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities , Training & Instructional Materials
  Outreach Resources and Activites

Population specific Web-based resources.   

Subject Terms: Population Groups , Public Health
Filters: Reference
  Pathways for Public Health Information

Guides to Web resources on environmental health and toxicology, disasters, chemicals, drugs, and special populations.   

Subject Terms: Consumer Health , Chemical Information , Disaster Information , Education , Environmental Health & Toxicology , Population Groups , Public Health
Filters: Reference
  Phenotype-Genotype Integrator (PheGenI)

Supports finding human phenotype/genotype relationships with queries by phenotype, chromosome location, gene, and SNP identifiers. Currently includes information from dbGaP, the National Human Genome Research Institute (NHGRI) genome-wide association study (GWAS) Catalog, and Genotype - Tissue Expression (GTeX).   

Subject Terms: Genetics & Genomics
Filters: Database , Training & Instructional Materials
  Physician’s Lives in the Shenandoah Valley

XML-encoded transcriptions and images of 828 handwritten letters (1786-1907) from the History of Medicine's Henkel Family correspondence collection; comprised largely of letters to and from Caspar C. Henkel (1835-1908).   

Subject Terms: History of Medicine
Filters: Database , Images , Reference
  Pillbox

Pillbox enables rapid identification of unknown solid-dosage medications (tablets/capsules) based on physical characteristics and high-resolution images.   

Subject Terms: Drugs & Supplements
Filters: Database , Images , API
  Pillbox API

Provides access to Pillbox’s data, including links to medication images.   

Subject Terms: Drugs & Supplements
Filters: Database , Images , API
  PMC Open Access Web Service

The service allows users to discover downloadable resources from the PMC Open Access Subset by providing an API to allow discovery of resources related to articles.   

Subject Terms: Literature
Filters: Dataset , API
  PMC Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH) Service

Provides access to metadata of all items in the PMC archive, and the full text of a subset of these items. PMC-OAI is an implementation of the Open Archives Initiative Protocol for Metadata Harvesting.   

Subject Terms: Literature
Filters: Dataset , API
  PopSet

Sets of DNA sequences that have been collected to analyze the evolutionary relatedness of a population.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Prescribable RxNorm API

The Prescribable RxNorm API is a web service for accessing the current RxNorm current prescribable content.   

Subject Terms: Drugs & Supplements , Health Data Standards , Terminologies
Filters:
  Primer-BLAST

The Primer-BLAST tool uses Primer3 to design PCR primers to a sequence template. The potential products are then automatically analyzed with a BLAST search against user specified databases, to check the specificity to the target intended.   

Subject Terms: Computational Biology
Filters: Tools & Utilities
  Profiles in Science

Archival collections of leaders in biomedical research and public health.   

Subject Terms: History of Medicine , Public Health
Filters: Images , Reference , API
  Profiles in Science API

Archival collections of leaders in biomedical research and public health. Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH) Service provides access to the Dublin Core metadata of items in archival collections.   

Subject Terms: History of Medicine , Public Health
Filters: Images , Reference , API
  ProSplign

A utility for computing alignment of proteins to genomic nucleotide sequence based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals.   

Subject Terms: Protein
Filters: Tools & Utilities
  Protein

Contains protein sequences from organisms. Includes data from a number of source databases such as GenPept (translations from annotated coding regions in GenBank), RefSeq, SwissProt, PIR, PRF, and PDB.   

Subject Terms: Protein
Filters: Database , Dataset , Tools & Utilities
  Protein Clusters

A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and protein function.   

Subject Terms: Protein
Filters: Database , Dataset , Tools & Utilities
  PSSM Viewer

Users can display, sort, subset and download position-specific score matrices (PSSMs) either from CDD records or from Position Specific Iterated (PSI)-BLAST protein searches.   

Subject Terms: Computational Biology , Protein
Filters: Tools & Utilities
  PubChem

PubChem is organized as three linked databases (PubChem Substance, PubChem Compound, PubChem BioAssay) within the Entrez system. Links from PubChem's chemical structure records to other Entrez databases provide information on biological properties.   

Subject Terms: Chemistry
Filters: Dataset
  PubChem BioAssay

Contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure.   

Subject Terms: Biological Assay , Chemistry
Filters: Database , Dataset , Tools & Utilities
  PubChem Compound

Derived from PubChem Substance this NCBI database provides a non-redundant view of the chemically validated substances in PubChem Substance. There is one PubChem Compound record for each unique substance, and for each unique substance component.   

Subject Terms: Chemistry
Filters: Database
  PubChem Download Service

This service allows users to download compound or substance records corresponding to a set of PubChem identifiers, which can be supplied manually or through a text file. Numerous download formats are available, including SDF, XML and SMILES.   

Subject Terms: Chemistry
Filters: Database , Dataset , Tools & Utilities
  PubChem Power User Gateway (PUG)

The PubChem Power User Gateway (PUG) provides access to PubChem services via a programmatic interface for retrieving information on the biological activities of small molecules. PUG provides access to these PubChem services: Data Download (substance and compound), Compound Structure Search, BioAssay Data Download and Structure Standardization.   

Subject Terms: Chemistry
Filters: Database , Dataset , Tools & Utilities
  PubChem Standardization Service

Standardization, in PubChem terminology, is the processing of chemical structures in the same way used to create PubChem Compound records from contributors' original structures. Users can see how PubChem handles structures they would like to submit.   

Subject Terms: Chemistry
Filters: Dataset , Tools & Utilities
  PubChem Structure Search

PubChem Structure Search allows the PubChem Compound Database to be queried by chemical structure or chemical structure pattern. The PubChem Sketcher allows a query to be drawn manually.   

Subject Terms: Chemistry
Filters: Database
  PubChem Substance

Chemical substance information electronically submitted to PubChem by depositors. This includes any chemical structure information submitted, as well as chemical names, comments, and links to the depositor's Web site.   

Subject Terms: Chemistry
Filters: Database , Dataset , Tools & Utilities
  PubChem Upload

Use this site to contribute new data to PubChem and/or test data upload procedures. Create a test account to test the deposition procedures and to preview data records then move on to a deposition account to upload data to the public database.   

Subject Terms: Chemistry
Filters: Tools & Utilities
  Public Health Partners (PHPartners)

Information access for the public health workforce.   

Subject Terms: Public Health
Filters: Reference
  PubMed

PubMed comprises more than 20 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher Web sites.   

Subject Terms: Books , Literature
Filters: Database , Dataset
  PubMed Central (PMC)

Free digital archive of full text biomedical and life sciences journal literature.   

Subject Terms: Literature
Filters: Database , Dataset
  PubMed Central Open-Access Subset

This small subset of articles in PMC are made available under a Creative Commons or similar license that generally allows more liberal redistribution and reuse than a traditional copyright. Refer to the license statement in each article for details.   

Subject Terms: Literature
Filters: Dataset
  PubMed Clinical Queries

A specialized PubMed search form targeted to clinicians and health services researchers. The page simplifies searching by clinical study category, finding systematic reviews and searching the medical genetics literature.   

Subject Terms: Literature
Filters: Database
  PubMed for Handhelds

Search MEDLINE with the Web browser of any mobile device.   

Subject Terms: Literature
Filters: App
  PubMed Mobile

A simplified mobile friendly Web interface to access PubMed which includes over 20 million citations for biomedical literature from MEDLINE, life science journals, and online books.   

Subject Terms: Books , Literature
Filters: Database , App
  PubMed Special Queries

Directory of topic-specific PubMed queries including AIDS, Bioethics, Cancer, Space Life Sciences as well as Clinical Queries along with many other search strategies.   

Subject Terms: Literature , Public Health
Filters: Database , Reference
  PubMed Tutorial

The NLM comprehensive tutorial on PubMed scope, content and features, including an in-depth explanation of PubMed Automatic Term Mapping (ATM).   

Subject Terms: Education
Filters: Training & Instructional Materials
  Radiation Emergency Medical Management (REMM)

Designed for health care providers, primarily physicians, without formal expertise in radiation safety or radiation medicine who may provide medical care during an accidental or non-accidental radiation event.   

Subject Terms: Disaster Information , Environmental Health & Toxicology , Hazardous Substances
Filters: Database , Dataset , Reference , Training & Instructional Materials , App
  Radiation Emergency Medical Management (REMM) Mobile

Guidance for health care providers on the diagnosis and treatment of radiation injuries during radiation and nuclear emergencies via a mobile app.   

Subject Terms: Disaster Information , Environmental Health & Toxicology , Hazardous Substances
Filters: Database , Dataset , Reference , Training & Instructional Materials , App
  Reference Sequence (RefSeq)

A collection of curated, non-redundant genomic DNA, transcript (RNA), and protein sequences produced by NCBI. Provides a stable reference for genome annotation, gene identification and characterization, and comparative analysis.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Database , Dataset
  RefSeqGene

RefSeqGene, a subset of NCBI's Reference Sequence (RefSeq) project, defines genomic sequences to be used as reference standards for well-characterized genes. These sequences, are labeled with the keyword RefSeqGene in NCBI's nucleotide database.   

Subject Terms: Computational Biology , Genetics & Genomics , Health Data Standards
Filters: Database , Dataset , Tools & Utilities
  Related Structures

The Related Structures tool allows users to find 3D structures from the Molecular Modeling Database (MMDB) that are similar in sequence to a query protein.   

Subject Terms: Protein
Filters: Tools & Utilities
  Research Reporting Guidelines and Initiatives: By Organization

A chart of the major biomedical research reporting guidelines that provide advice for reporting research methods and findings.   

Subject Terms: Research Reporting Guidelines
Filters: Reference
  Retrovirus Resources

A collection of resources designed to support the research of retroviruses, including a genotyping tool, alignment tool for global alignment of multiple sequences, a HIV-1 automatic sequence annotation tool, and annotated maps of many retroviruses.   

Subject Terms: Virus
Filters: Database , Reference , Tools & Utilities
  RxClass

An application for exploring drug classes and their RxNorm drug members. RxClass provides access to various drug classification systems, including ATC, NDF-RT, DailyMed and MeSH. RxClass is supported by the RxClass APIs.   

Subject Terms: Classification , Drugs & Supplements , Terminologies
Filters: Database , Dataset , API
  RxClass API

Provides developers with functions for linking RxNorm drugs to various drug classification systems, including ATC, NDF-RT, DailyMed and MeSH. Typical use cases include finding the class(es) for a given drug and finding all the drug members in a given class. Two RxClass APIs (SOAP/WSDL and RESTful) are available for retrieving drug class information.   

Subject Terms: Drugs & Supplements , Terminologies
Filters: Database , Dataset , API
  RxImage API

A developing information infrastructure for identifying unknown oral solid dosage pharmaceuticals (pills) to generate a comprehensive portfolio of digital images of those pills along with supplementary metadata for computer vision research.   

Subject Terms: Drugs & Supplements
Filters: Images , API
  RxMix

An interface for building applications that allows users to combine functions of various NLM drug APIs, including the RxNorm, RxClass, RxTerms, and NDF-RT APIs. Sequences of functions can be executed interactively or in batch mode.   

Subject Terms: Drugs & Supplements
Filters: Tools & Utilities , API
  RxNav

An application for navigating RxNorm drugs. This applications displays relations among drug entities in RxNorm and provides additional information about RxNorm drugs, including drug classes, pill images and drug-drug interactions. RxNav is supported by several drug APIs.   

Subject Terms: Drugs & Supplements
Filters: Database , API
  RxNorm

A standardized nomenclature for clinical drugs.   

Subject Terms: Drugs & Supplements , Health Data Standards , Terminologies
Filters: Dataset , API
  RxNorm API

Provides developers with functions for retrieving RxNorm data from the most current RxNorm data set. Typical use cases include mapping drug codes to RxNorm and linking among drug entities in RxNorm (e.g., branded drug to ingredient). Two RxNorm APIs (SOAP/WSDL and RESTful) are available for retrieving RxNorm data.   

Subject Terms: Drugs & Supplements , Health Data Standards , Terminologies
Filters: Dataset , API
  RxTerms API

RxTerms is a drug interface terminology derived from RxNorm for prescription writing or medication history recording. Two RxTerms APIs (SOAP/WSDL and RESTful) are available for retrieving RxTerms data.   

Subject Terms: Drugs & Supplements , Health Data Standards , Terminologies
Filters: Dataset , API
  SARS CoV

A summary of data for the SARS coronavirus (CoV), including: links to the most recent sequence data and publications, links to other SARS related resources, and a pre-computed alignment of genome sequences from various isolates.   

Subject Terms: Virus
Filters: Reference , Tools & Utilities
  Semantic Knowledge Representation (SKR) API

Indexing Initiative Web API provides access to the entire suite of Indexing Initiative and Semantic Knowledge Representation tools including MetaMap, Medical Text Indexer (MTI), and SemRep, and allows programmatic access to the Indexing Initiative Batch and Interactive facilities.   

Subject Terms: Computational Biology , Terminologies
Filters: API
  Sequence Cytogenetic Conversion Service

An online tool that converts sequence and cytogenetic coordinates for human, rat, mouse and fruit fly genomic assemblies.   

Subject Terms: Genetics & Genomics
Filters: Database , Tools & Utilities
  Sequence Read Archive (SRA)

The Sequence Read Archive (SRA) stores sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome Analyzer®, Life Technologies AB SOLiD System®, Helicos Biosciences Heliscope®, Complete Genomics®, and Pacific Biosciences SMRT®.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Sequence Read Archive (SRA) Download Facility

This site contains next-generation sequencing data organized by the submitted sequencing project.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset , Tools & Utilities
  Single Nucleotide Polymorphism (dbSNP)

Database of single nucleotide polymorphisms (dbSNP), small-scale insertions/deletions, polymorphic repetitive elements, and microsatellite variation.   

Subject Terms: Genetics & Genomics
Filters: Database
  SNOMED CT

SNOMED CT is one of a suite of designated standards for use in U.S. Federal Government systems for the electronic exchange of clinical health information and is also a required standard in interoperability specifications of the U.S. Healthcare Information Technology Standards Panel.   

Subject Terms: Health Data Standards , Terminologies
Filters: Database , Dataset , API
  SNOMED CT Status API

The SNOMED CT Status API is a web service for accessing the current status of SNOMED CT concepts.   

Subject Terms: Health Data Standards , Terminologies
Filters:
  SNP Database Specialized Search Tools

Search by genotype, method, population, submitter, markers and sequence similarity.   

Subject Terms: Genetics & Genomics
Filters: Database , Dataset
  SPDI Variation Service

This genetic variation services interconvert and transform short genetic variants between HGVS expressions, VCF format, and the new SPDI (Sequence Position Deletion Insertion) format, based on alignment datasets used by ClinVar and dbSNP.   

Subject Terms: Data Specifications , Genetics & Genomics , Molecular Biology
Filters: Tools & Utilities , API
  Splign

Compute cDNA-to-Genomic sequence alignments.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Tools & Utilities
  Structure (Molecular Modeling Database)

General information about the National Center for Biotechnology Information (NCBI) Structure Group and its research projects, as well as access to the Molecular Modeling Database (MMDB) and related tools.   

Subject Terms: Molecular Biology
Filters: Database , Tools & Utilities
  Structured Abstracts

Information about abstracts with distinct, labeled sections (e.g., Introduction, Methods, Results, discussion) that appear in MEDLINE.   

Subject Terms: Literature
Filters: Dataset
  Submission Portal

A single entry point for users to link to and find information about data submission processes at NCBI.   

Subject Terms: Biotechnology
Filters: Tools & Utilities
  Taxonomy

Contains the names and lineages of organisms, both living and extinct, that are represented in the genetic databases with at least one nucleotide or protein sequence. New organisms are added to the database as sequence data are deposited for them.   

Subject Terms: Biology , Classification
Filters: Database , Dataset
  Taxonomy Browser

Search the taxonomy tree using partial taxonomic names, common names, wild cards and phonetically similar names.   

Subject Terms: Biology , Classification
Filters: Database , Tools & Utilities
  Taxonomy Common Tree

Generates a taxonomic tree for a selected group of organisms. Users can upload a file of taxonomy IDs or names, or they can enter names or IDs directly.   

Subject Terms: Biology , Classification
Filters: Tools & Utilities
  Taxonomy Statistics

Displays the number of taxonomic nodes in the database for a given rank and date of inclusion.   

Subject Terms: Biology , Classification
Filters: Tools & Utilities
  Taxonomy Status Reports

Displays the current status of a set of taxonomic nodes or IDs.   

Subject Terms: Biology , Classification
Filters: Tools & Utilities
  Third Party Annotation (TPA) Database

A database that contains sequences built from the existing primary sequence data in GenBank. The sequences and corresponding annotations are experimentally supported and have been published in a peer-reviewed scientific journal.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Database
  Tox App

A free mobile app for iOS users based on the web-based NLM TOXMAP. Users can search for industrial facilities that reported releasing certain chemicals into the environment (based on data from the United States Environmental Protection Agency Toxics Release Inventory (TRI) program). Tox-App includes ~465 chemicals that were released on-site in TRI2016.   

Subject Terms: Consumer Health , Chemical Information , Environmental Health & Toxicology , Geographic Information System , Hazardous Substances , Public Health
Filters: App
  Tox Town

Guide to connections between chemicals, the environment, and the public's health.   

Subject Terms: Consumer Health , Environmental Health & Toxicology
Filters: Database , Training & Instructional Materials
  Toxicology Literature Online (TOXLINE)

Over 3 million references to the toxicological literature.   

Subject Terms: Environmental Health & Toxicology , Literature
Filters: Database , Dataset
  Toxicology Tutorials

College-level tutorials on the basic principles of toxicology, toxicokinetics, and cellular toxicology.   

Subject Terms: Environmental Health & Toxicology
Filters: Training & Instructional Materials
  Toxics Release Inventory (TRI)

Annual estimated releases of toxic chemicals into the environment by industrial facilities in the United States.   

Subject Terms: Consumer Health , Chemical Information , Environmental Health & Toxicology , Hazardous Substances , Public Health
Filters: Database , Dataset
  TOXMAP

Uses maps of the United States to show the amount and location of toxic chemicals released into the environment.   

Subject Terms: Consumer Health , Chemical Information , Environmental Health & Toxicology , Geographic Information System , Hazardous Substances , Public Health
Filters: Database , Training & Instructional Materials
  TOXNET (Toxicology Data Network )

A cluster of databases covering toxicology, hazardous chemicals, environmental health and related areas.   

Subject Terms: Environmental Health & Toxicology
Filters: Database , Dataset , Training & Instructional Materials , API , App
  TOXNET API

TOXNET API offers a RESTful Web Service API that allows users to search TOXNET databases with keywords.   

Subject Terms: Environmental Health & Toxicology
Filters: Database , Dataset , Training & Instructional Materials , API , App
  TOXNET Mobile

Easy to use, mobile-optimized Web interface to the TOXNET databases, covering toxicology, hazardous chemicals, environmental health and related areas.   

Subject Terms: Environmental Health & Toxicology
Filters: Database , Dataset , Training & Instructional Materials , API , App
  Trace Archive

A repository of DNA sequence chromatograms (traces), base calls, and quality estimates for single-pass reads from various large-scale sequencing projects.   

Subject Terms: Genetics & Genomics
Filters: Database , Tools & Utilities
  Turning the Pages

Explore beautiful historical medical texts using your desktop browser. These rare manuscripts come from a variety of regions and eras, from the Islamic medieval world to Renaissance Europe to 19th century Japan.   

Subject Terms: History of Medicine
Filters: Images , Multilanguage
  Turning the Pages Mobile

Explore beautiful historical medical texts with this app for your iPad. These rare manuscripts come from a variety of regions and eras, from the Islamic medieval world to Renaissance Europe to 19th century Japan.   

Subject Terms: History of Medicine
Filters: Images , Multilanguage , App
  Unified Medical Language System (UMLS)

Database of biomedical vocabularies (including SNOMED CT), and related semantic and lexical resource for system developers.   

Subject Terms: Health Data Standards , Terminologies
Filters: Database , Dataset , Multilanguage , API
  Unified Medical Language System (UMLS) Terminology Services API

Intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. Documentation provides a suite of Web Services Description Language (WSDL) files, API installation instructions, and sample code.   

Subject Terms: Health Data Standards , Terminologies
Filters: Database , Dataset , Multilanguage , API
  UniGene

An automated analytical system for producing organized views of the transcriptome from a growing number of organisms.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Database , Dataset
  UniVec

UniVec and UniVec_Core databases in FASTA format.   

Subject Terms: Computational Biology
Filters: Database , Dataset
  Value Set Authority Center (VSAC)

The VSAC is a repository and authoring tool for public value sets created by external programs such as Centers for Medicare & Medicaid Services (CMS) electronic Clinical Quality Measures (eCQMs), HL7 Consolidated Clinical Document Architecture (C-CDA), and the CMS Core Clinical Data Elements & Hybrid Measures.   

Subject Terms: Health Data Standards , Terminologies
Filters: Database , Dataset , API
  VecScreen

Quickly identifying segments of a nucleic acid sequence that may be of vector origin.   

Subject Terms: Genetics & Genomics
Filters: Tools & Utilities
  Vector Alignment Search Tool (VAST)

A computer algorithm that identifies similar protein 3-dimensional structures. Structure neighbors for every structure in MMDB are pre-computed and accessible via links on the MMDB Structure Summary pages.   

Subject Terms: Protein
Filters: Tools & Utilities
  Viral Genomes

Curated sequence data and related information for the community.   

Subject Terms: Genetics & Genomics , Virus
Filters: Database , Tools & Utilities
  Viral Genotyping Tool

This tool helps identify the genotype of a viral sequence.   

Subject Terms: Genetics & Genomics , Virus
Filters: Tools & Utilities
  Virus Variation

Extension of the Influenza Virus Resource to other organisms, providing an interface to download sequence sets of selected viruses; analysis tools, including virus-specific BLAST pages; and genome annotation pipelines (in progress).   

Subject Terms: Genetics & Genomics , Virus
Filters: Dataset , Tools & Utilities
  Visible Human Project

Three-dimensional representations of the human male and female bodies.   

Subject Terms: Anatomy , Medical Imaging
Filters: Dataset , Images , Multilanguage
  Voyager

Client/server protocol for fielded search and retrieval of MARC bibliographic records from the NLM integrated library system (ILS). Retrieve in MARC-8 or UTF-8 character encodings.   

Subject Terms: Library Services
Filters: Database
  Water Emergency Response for Libraries

Steps on what you should do after a water emergency in your library or cultural heritage institution.   

Subject Terms: Disaster Information
Filters: Reference
  Whole Genome Shotgun Sequences

Whole genome shotgun sequence data organized by the 4-digit project code. Data include GenBank and GenPept flat files, quality scores and summary statistics.   

Subject Terms: Computational Biology , Genetics & Genomics
Filters: Dataset
  Wireless Information System for Emergency Responders (WISER)

Assists first responders in hazardous material incidents.   

Subject Terms: Disaster Information , Environmental Health & Toxicology , Hazardous Substances
Filters: Database , Dataset , Reference , Tools & Utilities , Training & Instructional Materials , App