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News Release
Nov. 1, 2018
Up to one in every 10 pregnancies in the United States is affected by gestational diabetes, a type of diabetes found for the first time when a woman is pregnant.
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News Release
Oct. 9, 2018
Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a distinct advantage over those who do not.
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News Release
Oct. 3, 2018
Half of BetaFat study participants underwent a gastric banding procedure, which narrows the upper part of the stomach to slow digestion.
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News Release
Oct. 2, 2018
The National Institutes of Health has awarded 89 grants that will provide funding to extraordinarily creative scientists proposing highly innovative research to address major challenges in biomedical science. The grants are part of the NIH High-Risk, High-Reward Research Program, which supports ideas with potential for great impact in biomedical research from across the broad scope of the NIH.
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News Release
Oct. 1, 2018
The trans-NIH initiative will investigate critical health and quality-of-life needs for individuals with Down syndrome.
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News Release
Sept. 11, 2018
Mothers with elevated blood glucose during pregnancy – even if not high enough to meet the traditional definition of gestational diabetes – were significantly more likely to have developed type 2 diabetes a decade after pregnancy than their counterparts without high blood glucose.
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News Release
Aug. 14, 2018
Diabetes affects a body from head to toe. Now there’s a resource that illustrates its effect on both – and all the parts in between.
Thanks to research, what we know about diabetes and how to treat it has grown vastly over time. Now, researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health – along with leading diabetes experts from around the country and world – have developed the third edition of a reference designed to be a one-stop source for crucial scientific information on diabetes and its complications: “Diabetes in America.”
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News Release
Aug. 7, 2018
An intervention designed to help first-time mothers effectively respond to their infant’s cues for hunger, sleep, feeding, and other infant behaviors significantly improved the body mass index (BMI) z-scores of the child through age 3 years compared with the control group.
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News Release
July 25, 2018
Preliminary findings from a large clinical trial, the Systolic Blood Pressure Intervention Trial (SPRINT) Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study will be presented at the Alzheimer’s Association International Conference in Chicago on July 25.
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News Release
July 24, 2018
The National Institutes of Health’s Health Care Systems (HCS) Research Collaboratory, which involves health care systems in conducting large-scale clinical studies, has announced five new research awards—totaling $4.15 million for a one-year planning phase, with an estimated $30.85 million expected for four subsequent years of study implementation.
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News Release
June 25, 2018
In youth with impaired glucose tolerance or recent-onset type 2 diabetes, neither initial treatment with long-acting insulin followed by the drug metformin, nor metformin alone preserved the body’s ability to make insulin, according to results published online June 25 in Diabetes Care.
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News Release
June 13, 2018
Giving children intravenous (IV) fluids to treat diabetic ketoacidosis — an emergency complication of untreated diabetes — does not appear to worsen the brain swelling that may accompany the condition, according to a study supported by the National Institutes of Health.
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News Release
May 30, 2018
NIH-funded study illustrates how evolution may shape the senses.
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News Release
May 24, 2018
Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver.
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News Release
May 21, 2018
Gestational diabetes may predispose women to early-stage kidney damage, a precursor to chronic kidney disease, according to a study by researchers at the National Institutes of Health and other institutions.
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News Release
May 7, 2018
Study follows passage of HOPE Act of 2013, allowing people with HIV to become organ donors.
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News Release
May 1, 2018
Obesity is a major contributor to serious health conditions in children and adults.
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News Release
March 21, 2018
Quality of life for people with type 1 diabetes who had frequent severe hypoglycemia — a potentially fatal low blood glucose (blood sugar) level — improved consistently and dramatically following transplantation of insulin-producing pancreatic islets, according to findings published online March 21 in Diabetes Care.
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News Release
March 8, 2018
On World Kidney Day, the NIDDK urges women to adopt healthy lifestyle habits and inspire family and friends to do the same.
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Research Update
Feb. 1, 2018
Researchers have found that a genetic variant may impart risk for inflammatory bowel disease (IBD) by disrupting the cellular “glue” that keeps the gut’s lining intact.
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Research Update
Jan. 8, 2018
New research suggests a mechanism by which antenna-like sensory projections, called primary cilia, located on brain cells play a role in the genetic predisposition to and development of obesity.
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Research Update
Jan. 7, 2018
In a controlled study of weight gain and loss, researchers have assembled a comprehensive molecular profile of dramatic changes that occur in humans during short periods of weight fluctuation.
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Research Update
Dec. 22, 2017
Scientists’ recent analysis of hundreds of thousands of human genomes has identified new links between certain gene sequence variations and body mass index (BMI), a measure of weight relative to height.
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Research Update
Dec. 19, 2017
An international group of researchers revealed several areas of the human genome that convey risk for developing primary sclerosing cholangitis, a disease that can lead to liver damage.
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Research Update
Nov. 28, 2017
Researchers have identified two different molecules that can limit growth of microbes that cause urinary tract infections (UTIs), adding to approaches being pursued to develop new strategies for clinical treatment of UTIs.
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Research Update
Nov. 22, 2017
A recent study has established a correlation between the level of fibroblast growth factor-23 (FGF-23) in the blood of a person with chronic kidney disease (CKD), measured over time, and the risk of death.
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Research Update
Nov. 22, 2017
Researchers have identified a protein present at high levels in blood from infants with biliary atresia that may enable early and accurate detection of this potentially deadly disease.
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Research Update
Nov. 20, 2017
Scientists have developed a new way to replace lost beta cells in mouse models of type 1 diabetes.
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Research Update
Nov. 15, 2017
Using human samples and animal models, researchers have found that an enzyme produced by certain bacteria could disrupt the gut microbiome, potentially playing a significant role in the development of inflammatory bowel disease.
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News Release
Nov. 13, 2017
Obesity during pregnancy — independent of its health consequences such as diabetes — may account for the higher risk of giving birth to an atypically large infant, according to researchers at the National Institutes of Health. Their study appears in JAMA Pediatrics.
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News Release
Nov. 6, 2017
For the first time, scientists have found a connection between abnormalities in how the brain breaks down glucose and the severity of the signature amyloid plaques and tangles in the brain, as well as the onset of eventual outward symptoms, of Alzheimer’s disease.
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Research Update
Nov. 3, 2017
A clinical trial led by a pharmaceutical company with additional support from an NIDDK-supported Cystic Fibrosis Center has shown that a combination of two medications provides significant clinical benefit in a subgroup of patients with cystic fibrosis (CF).
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Research Update
Nov. 1, 2017
In a clinical trial, researchers found that as people lost weight, their appetite and calorie consumption increased, leading to a leveling off of weight loss.
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News Release
Nov. 1, 2017
More than 30 million people in the United States have diabetes – and each one is the most important member of their diabetes care team. This National Diabetes Month, I urge everyone with diabetes to make your care a joint effort between you, your loved ones and your health care team.
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Research Update
Oct. 26, 2017
Scientists found that feeding mice twice a day, with complete food restriction in between, improved metabolism and prevented age- and obesity-associated metabolic defects compared to allowing them 24-hour access to food.
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Research Update
Oct. 5, 2017
Researchers identified two factors that contribute to the critical balance of food intake and calorie burning in mice.
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Research Update
Oct. 3, 2017
Researchers have found that the sugars fructose and glucose cause different metabolic effects and health outcomes in mice, but only in animals eating a high-fat diet.
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News Release
Oct. 2, 2017
The 2017 Nobel Prize in Physiology or Medicine has been awarded to National Institutes of Health grantees Jeffrey C. Hall, Ph.D., of the University of Maine, Orono; Michael Rosbash, Ph.D., of Brandeis University, Waltham, Massachusetts; and Michael W. Young, Ph.D., of Rockefeller University, New York City, for their discoveries of molecular mechanisms controlling the circadian rhythm.
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Research Update
Sept. 28, 2017
Researchers have used sophisticated technologies to examine individual cells from healthy human pancreata to understand how the cells change with age.
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Research Update
Sept. 21, 2017
A long-term study of gastric bypass surgery has shown lasting weight loss and effective remission and prevention of type 2 diabetes for more than a decade.
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Research Update
Sept. 19, 2017
Results of NIDDK-supported research have improved understanding of factors that can help predict vulnerability to severe hypoglycemia in African American and white individuals with type 2 diabetes.
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News Release
Sept. 13, 2017
Can a high-tech water bottle help reduce the recurrence of kidney stones? What about a financial incentive? Those are questions researchers funded by the National Institutes of Health will seek to answer as they begin recruiting participants for a two-year clinical trial at four sites across the country. Scientists will test whether using a smart water bottle that encourages people to drink more water, and therefore urinate, will reduce the recurrence of urinary stone disease, commonly referred to as kidney stones. The trial is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of NIH.
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News Release
Sept. 12, 2017
More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models. To help combat this translational science problem, the National Institutes of Health announced 13 two-year awards totaling about $15 million per year, with FY18 funds subject to availability, to develop 3-D microphysiological system platforms that model human disease. The funding is for the first phase of a five-year program. These platforms, called “tissue chips,” support living cells and human tissues to mimic the complex biological functions of human organs and systems and provide a new way to test potential drug efficacy.
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Research Update
Sept. 5, 2017
A new study found that in people who do not have chronic kidney disease (CKD), an intensive blood pressure control regimen increases risk of declining kidney function; this risk is generally outweighed by a reduced risk for cardiovascular events and death.
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Research Update
Sept. 5, 2017
Molecules produced by friendly gut bacteria could extend the time that worms, flies, and mice remain healthy during their lives—with potential implications for human health.
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Research Update
Aug. 30, 2017
Proteins involved in ensuring that other proteins are in their proper shapes may have a role to play in mitigating the effects of cystic fibrosis.
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Research Update
Aug. 26, 2017
New insights into outcomes from drug-induced liver injury include the rate of fatal outcomes, frequency of bile duct damage and loss, and racial/ethnic disparities in disease severity.
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Research Update
Aug. 25, 2017
Seasonal variability in the gut microbiome of a traditional hunter-gatherer population in Tanzania provides new insights into how diet and modernization may affect bacteria in the gut.
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Research Update
Aug. 14, 2017
Researchers have identified a protein in the mouse brain responsible for the metabolic syndrome caused by an antipsychotic medication.
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Research Update
Aug. 14, 2017
A newly identified molecular factor key to the activation of energy-burning brown fat could further possibilities for obesity treatment.