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U.S. Department of Health & Human Services

National Institutes of Health

Rare Diseases Clinical Research Network (RDCRN)

child with a rare disease

The RDCRN program is designed to advance medical research on rare diseases by providing support for clinical studies and facilitating collaboration, study enrollment and data sharing. Through the RDCRN consortia, physician scientists and their multidisciplinary teams work together with patient advocacy groups to study more than 200 rare diseases at sites across the nation.

NCATS, FDA Co-Host Workshop on Gene Therapy for Rare Diseases

NCATS and the Food and Drug Administration are collaborating to identify bottlenecks to gene therapy development and share best practices for advancing gene therapies.

child with a rare disease

RDCRN eos

Team Identifies Three Distinct Forms of Rare Food Allergy Disease

With support from the Rare Diseases Clinical Research Network, scientists have developed a personalized approach to diagnosing and treating eosinophilic esophagitis.

RDCRN brain

Potential Gene-Editing Treatment Advances to Clinical Trials

RDCRN-supported researchers charted how several rare diseases progressed in patients over time, helping to enable a potential gene-editing therapy to advance to clinical trials.

About the RDCRN

Learn more about the RDCRN program and its network of study sites.

RDCRN in Action

RDCRN Funding Information

Find out about funding opportunities, how to apply and how to collaborate.

Current RDCRN Consortia

Discover the 22 consortia and their central data management and coordinating center.

Rare Diseases Health Information

Access information about rare diseases for patients and researchers.

About the RDCRN

About the RDCRN

Learn more about the RDCRN program and its network of study sites.

RDCRN in Action

RDCRN Funding Information

RDCRN Funding Information

Find out about funding opportunities, how to apply and how to collaborate.

Current RDCRN Consortia

Current RDCRN Consortia

Discover the 22 consortia and their central data management and coordinating center.

Rare Diseases Health Information

Rare Diseases Health Information

Access information about rare diseases for patients and researchers.

Work with Us

Tiina Urv, Ph.D.

RDCRN Facts

Download the RDCRN fact sheet (PDF - 184KB).

Learn about the RDCRN

The RDCRN program is designed to advance medical research on rare diseases by providing support for clinical studies and facilitating collaboration, study enrollment and data sharing. Through the RDCRN consortia, physician scientists and their multidisciplinary teams work together with patient advocacy groups to study more than 200 rare diseases at sites across the nation.

Genetic and Rare Diseases Information Center (GARD)

GARD provides up-to-date health information about numerous rare and genetic diseases.

NCATS Programs & Initiatives

3-D Tissue Bioprinting Program

A Specialized Platform for Innovative Research Exploration

Assay Development and Screening Technology

Assay Guidance Manual

Biomedical Data Translator

Bridging Interventional Development Gaps

Chemistry Technology

Clinical and Translational Science Awards Program

Discovering New Therapeutic Uses for Existing Molecules

Genetic and Rare Diseases Information Center

Matrix Combination Screening

NCATS Chemical Genomics Center

NCATS' Role in the NIH HEAL Initiative^SM

NCATS Toolkit for Patient-Focused Therapy Development

NIH Common Fund Programs

Pfizer's Centers for Therapeutic Innovation

Rare Diseases Registry Program

Rare Diseases Clinical Research Network

Trans-NIH RNAi Facility

Small Business Innovation Research & Small Business Technology Transfer

Therapeutics for Rare and Neglected Diseases

Tissue Chip for Drug Screening

Toxicology in the 21st Century

Access NCATS Expertise & Resources

NCATS Programs & Initiatives