The NICHD conducts and supports a variety of clinical research related to women’s health. Select a link below to learn more about these projects.
Featured NICHD Clinical Trials on Women’s Health
- Global Study of Women’s Health
This large-scale study will study whether women with endometriosis-related pelvic pain are affected differently than those with pelvic pain from other or no identifiable causes. The goals of this study are to provide insights into the effects of the condition and associated symptoms on women’s lives across different countries, as well as explore differences in the effects of various potential risk factors. - Evaluation of Women With Endocrine and Reproductive-Related Conditions
This study will evaluate women with a variety of reproductive and endocrine-related disorders for research and physician education. Evaluations may include ultrasound examinations as well as blood, saliva, and/or urine samples. These evaluations and treatments will support clinical training and research for the accredited training program in reproductive endocrinology at the NICHD. - Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission
The purpose of this study is to collect and study clinical and laboratory information about a pregnant or new mother and her medical care that will increase knowledge of the best care for HIV-infected pregnant women and their children. This study will monitor the health of women and their infants while they receive anti-HIV therapy. In addition, this study will provide information that may be used for future studies. - Dil Mil (Hearts Together)
A growing body of research indicates that gender-based violence (GBV) is a major global public health challenge. However, there is little evidence to guide program planning and policy-making efforts to reduce GBV. This study will evaluate the feasibility, safety, and potential effectiveness of an innovative women’s empowerment intervention to reduce GBV and related adverse health outcomes. It is expected that the study findings will provide evidence to determine if a phase III effectiveness trial is merited and advance the science underlying GBV prevention. - Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b)
This study focuses on the 40% of pregnant American women who have never given birth. Little prior research has been done on this group. The goal of this study is to find ways to identify women who might develop a problem during their pregnancy. The study focuses on high blood pressure, preterm delivery, and low-birth-weight babies. - Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA)
The purpose of this randomized, open-label, active-control trial is to compare the effectiveness of intra-detrusor botulinum toxin A (Botox A®, Allergan) versus sacral neuromodulation (InterStim®, Medtronic) for the treatment of refractory urge urinary incontinence. In addition, the study will evaluate select technical attributes of the interventions as well as the effect of these two interventions on other lower urinary tract and pelvic floor symptoms. - The Natural History of Reproductive and Overall Health in Girls and Women with a Pre-Mutation in the FMR1 Gene; Creation of a Patient Registry
Creating a patient registry of women who have an abnormality in the Fragile X (FMR1) gene will allow researchers to follow participants over time and study possible effects of this abnormality on their general and reproductive health. - Botulinum Toxin for Pelvic Pain in Women with Endometriosis
This study will determine if botulinum toxin injections into the pelvic floor muscles can decrease pain and spasms in women with pelvic pain caused by endometriosis.
NICHD Clinical Trials
ClinicalTrials.gov Search Results
Information on current NIH-sponsored clinical trials on women’s health is available at the link below or by calling 1-800-411-1222.
BACK TO TOP