![This image shows Keratin 5 (red) and Keratin 1 (green) expression in skin tumors. Keratins are fibrous structural proteins present in epithelial structures, such as skin, hair, and nails. They form filaments that give strength and toughness to the structures. Keratins are often used to assist in the diagnosis of squamous cell carcinoma, a form of skin cancer. Credit: Laboratory of Skin Biology Keratin 5 (red) and Keratin 1 (green) expression in skin tumors.](/congress115th/20190108201309im_/https://www.niams.nih.gov/sites/default/files/images/large/keratin-skin-tumors-lab-banner.jpg)
About the Labs
The NIAMS intramural research program (IRP) conducts innovative basic, translational, and clinical research in a number of research areas. The world-class investigators, staff and trainees in the IRP work to gain new insights into the normal function of the immune system, bones, joints, muscles, and skin, and the diseases that affect them, and translate these insights into novel diagnostic tools and treatments. The IRP is supported by cutting-edge core facilities and interacts with the other intramural programs at the NIH, one of the premier sites in the world where biomedical research and clinical investigation are combined on one campus.
Training the next generation of researchers and clinical investigators in our areas of interest, including rheumatologists, dermatologists, and orthopaedic surgeons, is a major focus of the IRP, with training positions at many levels. We invite you to explore this site and learn about our research labs, clinical trials and training programs.
John O’Shea, MD, Scientific Director
Robert A. Colbert, MD, PhD, Acting Clinical Director
Research Areas
Autoimmunity Branch
Biodata Mining and Discovery Section
Clinical and Investigative Orthopedics Surgery Unit
Clinical Research @ NIAMS
Clinical Trials and Outcomes Branch
Community Research and Care
Cutaneous Development and Carcinogenesis Section
Cutaneous Leukocyte Biology Section
Cutaneous Microbiome and Inflammation Section
Dermatology Branch
Dermatology Consultation Service
Flow Cytometry Section
Juvenile Arthritis Pathogenesis Unit
Laboratory Animal Care and Use Section
Laboratory of Molecular Immunogenetics
Laboratory of Muscle Stem Cells and Gene Regulation
Laboratory of Oral Connective Tissue Biology
Laboratory of Skin Biology
Laboratory of Structural Biology Research
Light Imaging Section
Lupus Clinical Trials Unit
Molecular Immunology and Inflammation Branch
Muscle Disease Unit
Muscle Energetics Laboratory
Office of Science and Technology
Pediatric Translational Research Branch
Protein Expression Laboratory
RNA Molecular Biology Group
Systemic Autoimmunity Branch
Translational Genetics and Genomics Unit
Translational Immunology Section
Vasculitis Translational Research Program
Resources
![doctor visiting with a patient](/congress115th/20190108201309im_/https://www.niams.nih.gov/sites/default/files/images/thumbnails/thumb_small_clinicaltrials_0.jpg)
Clinical Trials at NIAMS
Explore clinical research studies for diseases of the immune system, bones, joints, muscles, and skin.![scientists reviewing study results](/congress115th/20190108201309im_/https://www.niams.nih.gov/sites/default/files/images/thumbnails/thumb-small-studiesseeking_0.jpg)
Career Development at NIAMS
Explore customized training programs to enhance your research skills.![Gain research skills in one of the NIAMS labs.](/congress115th/20190108201309im_/https://www.niams.nih.gov/sites/default/files/images/thumbnails/thumb-small-careers_0.jpg)
Core Facilities
Learn about our state of the art instruments and technologies.![Join our labs as a career scientist.](/congress115th/20190108201309im_/https://www.niams.nih.gov/sites/default/files/images/thumbnails/thumb-small-join-niams.jpg)