NCATS Chemical Genomics Center (NCGC)

NCGC scientists bring unique expertise and diverse interests to research projects and collaborations to help kick-start the early discovery pathway. The team creates tools and technologies that enable the de-risking of potential targets and modalities for treating diseases. Learn more about NCGC.

New Approach to Identify Potential Cancer Drugs

NCATS researchers develop a series of assays (tests) to identify compounds that disrupt a driver of several cancers.

Finding What’s Common Among Diseases, Seeing the Bigger Picture

NCATS scientists are identifying common characteristics among diseases and applying this knowledge to understand multiple human diseases and conditions.

NCATS Ignites Translational Science Spark for Young Investigators

Meet three graduate students working collaboratively on research projects with NCATS and university scientists from England and Sweden.

About NCGC

Find out more about how NCGC experts help discover novel small molecule therapies across the spectrum of human diseases.

Scientific Capabilities

Access a collaborative team of experts in assay development, high-throughput screening, medicinal chemistry, informatics and drug development.

Work with NCGC

Learn how to collaborate with NCGC staff to pursue a drug target or screen of interest.

About NCGC

Find out more about how NCGC experts help discover novel small molecule therapies across the spectrum of human diseases.

Scientific Capabilities

Access a collaborative team of experts in assay development, high-throughput screening, medicinal chemistry, informatics and drug development.

Work with NCGC

Learn how to collaborate with NCGC staff to pursue a drug target or screen of interest.

Work with Us

NCGC is highly collaborative and always encourages new partnership opportunities, including projects with NIH and external researchers as well as disease foundations and biotechnology companies. Learn more about how to work with us.

Looking for a chemical probe?

NCGC experts have developed many small molecule probes for further therapeutic development.

NCATS Programs & Initiatives

3-D Tissue Bioprinting Program

A Specialized Platform for Innovative Research Exploration

Assay Development and Screening Technology

Assay Guidance Manual

Biomedical Data Translator

Bridging Interventional Development Gaps

Chemistry Technology

Clinical and Translational Science Awards Program

Discovering New Therapeutic Uses for Existing Molecules

Genetic and Rare Diseases Information Center

Matrix Combination Screening

NCATS Chemical Genomics Center

NCATS' Role in the NIH HEAL Initiative^SM

NCATS Toolkit for Patient-Focused Therapy Development

NIH Common Fund Programs

Pfizer's Centers for Therapeutic Innovation

Rare Diseases Registry Program

Rare Diseases Clinical Research Network

Trans-NIH RNAi Facility

Small Business Innovation Research & Small Business Technology Transfer

Therapeutics for Rare and Neglected Diseases

Tissue Chip for Drug Screening

Toxicology in the 21st Century

Access NCATS Expertise & Resources

NCATS Programs & Initiatives