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This is the beginning of a simple schematic depicting the longest mRNA-encoding exon/intron structure of the gene regionnon-coding regionexonnon-coding regionexonnon-coding regionexonnon-coding regionexonnon-coding regionexonnon-coding regionexonnon-coding regionexonnon-coding region
Click to Display mRNA-Genomic Alignments (spanning 32668 bps)
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   Homo sapiens Official Gene Symbol and Name (HGNC)
  MRAS: muscle RAS oncogene homolog
 LocusID: 22808
Overview ?
RefSeq Summary: Members of the RAS superfamily of GTP-binding proteins, which includes MRAS, are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors.[supplied by OMIM]
Locus Type: gene with protein product, function known or inferred
Product: muscle RAS oncogene homolog
Alternate Symbols: M-RAs, RRAS3, R-RAS3
Alias: muscle and microspikes RAS
FunctionSubmit GeneRIF(All Pubs)?

Please note: As a consequence of our transition to Entrez Gene, GeneRIFs will only be displayed in the Entrez Gene record for this locus. EntrezGene

      Gene OntologyTM:  
     Term Evidence Source Pub
     
  • GTP binding
    		•  IEA GOA  
     
  • GTPase activity
    		•  TAS GOA pm
     
  • Ras protein signal transduction
    		•  TAS GOA pm
     
  • actin cytoskeleton organization and biogenesis
    		•  TAS GOA pm
     
  • development
    		•  TAS GOA pm
     
  • muscle development
    		•  TAS GOA pm
     
  • plasma membrane
    		•  TAS GOA pm
    Relationships ?
      Mouse, Rat Homology Map Viewer  

    Map Information ?
      Chromosome:3   mv
      Cytogenetic:3q22.3  RefSeq 
      Markers: Chr. -WI-19950  
       Chr. -RH80075  
       Chr. -PMC181332P1  

    NCBI Reference Sequences (RefSeq)?

    Please note: Conserved protein domain information will only be displayed in Entrez Gene. You may find the information for this locus here: EntrezGene

    Category: PROVISIONAL
     mRNA: NM_012219    
     Protein: NP_036351  muscle RAS oncogene homolog BL
     GenBank Source: BC035939    

    Category: NCBI Genome Annotation
    1.Genomic Contig: NT_005612   gb sv mv ev mm
     Haplotype reference    
      Annotation for this locus:
     Evidence: supported by alignment with mRNA   
     mRNA: NM_012219    
     Protein: NP_036351   BL

    Category: NCBI Genome Annotation
    2.Genomic Contig: NT_086641   gb sv mv ev mm
     Haplotype Celera    
      Annotation for this locus:
     Evidence: supported by alignment with mRNA   
     mRNA: NM_012219    
     Protein: NP_036351   BL

    Related Sequences ?
    Nucleotide Type Protein   
    AF022080 m AAC52085   BL
    AF043938 m AAD02287   BL
    AF493918 m AAM12632   BL
    AK056337 m      
    AK091633 m      
    AK123833 m      
    BC017733 m AAH17733   BL
    BC035939 m      
    BC047101 m      
    BC047690 m AAH47690   BL
    None p O14807   BL

    Additional Links ?
     
     
     

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