Review Criteria for and Rating of Unsolicited Research Grant and Other Applications
NIH GUIDE, Volume 26, Number 22, June 27, 1997
P.T. 34
Keywords
Grants Administration/Policy
National Institutes of Health
Background
As part of the ongoing effort to maintain high standards for peer
review at the NIH, the Rating of Grant Applications (RGA) subcommittee
of the NIH Committee on Improving Peer Review was charged with examining
the process by which scientific review groups rate grant applications
and with making recommendations to improve that process in light
of scientific knowledge of measurement and decision making. The
charge was in response to the perception that the review of grant
applications needed to be refocused on the quality of the science
and the impact it might have on the field, rather than on details
of technique and methodology. After extensive discussion of the
RGA's report by NIH staff, the extramural community, and the Peer
Review Oversight Group (PROG), at the May 5, 1997, meeting of PROG
the director of NIH announced procedures to be used for the review
of research grant applications.
The procedures will be effective for all unsolicited
research project grant applications (including those in response to Program Announcements
published in the NIH Guide) submitted on or after October 1, 1997, most of which will be
reviewed starting in January/February 1998. Reviewers will be instructed to (a) address
the five review criteria below and (b) assign a single, global score for each scored
application. The score should reflect the overall impact that the project could have on
the field based on consideration of the five criteria, with the emphasis on each criterion
varying from one application to another, depending on the nature of the application and
its relative strengths.
The goals of NIH-supported research are to advance our
understanding of biological systems, improve the control of disease, and enhance health.
In the written comments reviewers will be asked to discuss the following aspects of the
application in order to judge the likelihood that the proposed research will have a
substantial impact on the pursuit of these goals. Each of these criteria will be addressed
and considered in assigning the overall score, weighting them as appropriate for each
application. Note that the application does not need to be strong in all categories to be
judged likely to have major scientific impact and thus deserve a high priority score. For
example, an investigator may propose to carry out important work that by its nature is not
innovative but is essential to move a field forward.
(1) Significance: Does this study address an important problem?
If the aims of the application are achieved, how will scientific
knowledge be advanced? What will be the effect of these studies
on the concepts or methods that drive this field?
(2) Approach: Are the conceptual framework, design,
methods, and analyses adequately developed, well-integrated, and appropriate to the aims
of the project? Does the applicant acknowledge potential problem areas and consider
alternative tactics?
(3) Innovation: Does the project employ novel concepts, approaches,
or method? Are the aims original and innovative? Does the project
challenge existing paradigms or develop new methodologies or technologies?
(4) Investigator: Is the investigator appropriately
trained and well suited to carry out this work? Is the work proposed appropriate to the
experience level of the principal investigator and other researchers (if any)?
(5) Environment: Does the scientific environment in which
the work will be done contribute to the probability of success? Do the proposed
experiments take advantage of unique features of the scientific environment or employ
useful collaborative arrangements?
Is there evidence of institutional support?
While the review criteria are intended for use primarily
with unsolicited research project applications (e.g., R01, R29, P01), to the extent
reasonable, they will also form the basis of the review of solicited applications and
non-research activities. However, for some activities (e.g., construction grants), use of
these criteria as stated may not be feasible.
In addition to the above criteria, in accordance with NIH
policy, all applications will also be reviewed with respect to the following:
- The adequacy of plans to include both genders, minorities,
and their subgroups as appropriate for the scientific goals of the research. Plans for the
recruitment and retention of subjects will also be evaluated.
- The reasonableness of the proposed budget and duration in
relation to the proposed research.
- The adequacy of the proposed protection for humans, animals, or the environment,
to the extent they may be adversely affected by the project proposed
in the application.
Requests for Applications (RFAs), which are published in
the NIH Guide to Grants and Contracts, will list the specific criteria for scientific peer
review of applications submitted in response to the particular RFA.
Inquiries
Inquiries regarding this notice may be directed to:
Dr. Janet Cuca
Office of Extramural Programs
National Institutes of Health
6701 Rockledge Drive, Room 6192
Bethesda, MD 20892
Phone: (301) 435-2691
Email: janet_cuca@nih.gov
|