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Vaccine Research Center
Scientific Updates
Smallpox Vaccine Development
The Vaccine Research Center is currently testing Modified
Vaccinia Ankara (MVA) as an attenuated poxvirus with the potential
to protect against vaccinia (the virus used to vaccinate against
smallpox) or variola (the virus that causes smallpox). The
vaccine was provided by Therion Biologics Corporation as part
of a collaboration with the VRC. Two Phase I clinical trials
are now underway testing MVA as a component of a safer smallpox
vaccine in both vaccinia naïve and vaccinia immune populations.
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