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Structural Model of Topoisomerase II
Caption:
Model illustrating a Type II topoisomerase protein encompassing a section of DNA (surrounded by the wreath of blue).
Topoisomerases are essential for untangling chromosomal DNA, which they do by cutting fragments and resealing them. As depicted by molecular models, pieces of DNA are ushered through the topoisomerase enzyme protein, which appears as a clamp with two sets of jaws at opposite ends, connected by multiple joints. This work was performed by James Berger.
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| Credit: |
Credit: ©Whitehead Institute for Biomedical Research |
| Decade of Image: |
2000 - 2009 |
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Categories:
BIOLOGICAL / Microbiology
Formats Available:
Restrictions:
No additional restrictions--beyond NSF's general restrictions--have been placed on this image. For a list of general restrictions that apply to this and all images in the NSF Image Library, see the section "Conditions".
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