NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Eye Institute (NEI)

46 Protocols (37 Active Accrual of new subjects, 9 Follow-up of previously enrolled subjects)

Active Accrual, Protocols Recruiting New Patients 
* 04-EI-0260:
Use of Immune Cell Markers, Cytokines, and Transcription Factors as Markers of Intraocular Inflammatory Activity

* 04-EI-0241:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Anterior Segment Disease

* 04-EI-0240:
Pilot Study of Intravitreal Injection of Ranibizumab (rhuFAB V2) for Advanced Ocular Disease of Von Hippel-Lindau Disease

* 04-EI-0190:
Pilot Study of Helicobacter Pylori and Ocular Surface Disease

* 04-EI-0166:
A Cross Sectional Clinical Study of Human Lens Aging and Cataract Formation, in Vivo, Using Dynamic Light Scattering (DLS)

* 04-EI-0157:
Evaluation and Treatment of Ocular Complications of Vaccinia Vaccination: Suitability of NP-016 Vaccinia Immune Globulin (VIG) for Sight-Threatening Conditions [VIG31]

* 04-EI-0128:
Evaluation of the Age-Related Eye Disease Study (AREDS) Clinical Lens Grading System

* 04-EI-0115:
Combination Daclizumab/Sirolimus Therapy For the Induction of Immune Tolerance in Non-Infectious Intermediate and Posterior Uveitis

* 04-EI-0065:
Evaluation of Infliximab in the Treatment of Non-Infectious Scleritis

* 04-EI-0048:
Digital Image Based Determination of Ocular Surface Vital Dye Staining

* 04-EI-0039:
Evaluation and Treatment of Pediatric, Developmental and Genetic Eye Disease

* 04-EI-0006:
Daclizumab for Active, Non-infectious, Sight-threatening Uveitis: A Phase II Pilot Study

* 03-EI-0294:
Optical Coherence Tomography Comparative Study

* 03-EI-0275:
Pilot Study on the Use of the NASA-NEI Dynamic Light Scattering (DLS) Device in Detecting lens Changes in the other Eye of Patients with Pre-Senile Cataracts

* 03-EI-0255:
Pilot Study on the Effect of Vitamin A Supplementation on Cone Function in Retinitis Pigmentosa

* 03-EI-0234:
A Phase I Study of NT-501-10 and NT-501-6A.02, Implants of Encapsulated Human NTC-210 Cells Releasing Ciliary Neurotrophic Factor (CNTF), in Patients with Retinitis Pigmentosa

* 03-EI-0179:
Investigation of the Effect of Dietary Docosahexaenoic Acid (DHA) Supplementation on Macular Function in Subjects with Autosomal Dominant Stargardt-Like and Autosomal Recessive Stargardt Macular Dystrophy

* 03-EI-0156:
Measurement of Macular Pigment with Resonant Raman Backscattering Spectroscopy

* 03-EI-0155:
Evaluation of Single Nucleotide Polymorphism (SNP) in Patients with and Subjects without Age-Related Macular Degeneration (AMD)

* 03-EI-0123:
Clinical and Molecular Studies in Families with Congenital or Hereditary Cataracts

* 03-EI-0068:
Identification of Biological Markers in Retinal Vasculitis

* 03-EI-0065:
Preliminary Multi-center Assessment of Laser and Medical Treatment of Diabetic Macular Edema

* 03-EI-0033:
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

* 03-EI-0012:
A Pilot Study Using the Dynamic Light Scattering Device (DLS) Combined with Keratoscopy on the Cornea in Vivo

* 02-EI-0255:
Prevalence and Risks for Posterior Subcapsular Cataracts in Volunteer Granulocytapheresis Donors

* 01-EI-0102:
Evaluation and Treatment Protocol for Potential Research Subjects with Inherited Ophthalmic Diseases

* 01-EI-0046:
Evaluation and Treatment Protocol of Patients with Corneal and External Diseases

* 00-EI-0204:
Evaluation and Treatment Protocol for Patients with Intraocular Inflammatory Disease (Uveitis)

* 00-EI-0139:
Evaluation and Treatment Protocol for Patients with Retinal Disease

* 00-EI-0135:
Study of Association of Serum Factors with Diabetic Retinopathy

* 99-EI-0035:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Nystagmus or Strabismus

* 98-EI-0085:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Ocular Inflammatory or Immunologic Diseases

* 98-EI-0076:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Retinovascular Diseases

* 98-EI-0072:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects with Inherited Ophthalmic Diseases

* 92-EI-0113:
Immunopathology of Ocular Diseases in Humans

* 86-EI-0062:
Trial of Topical Cysteamine in the Treatment of Corneal Cystine Crystal Accumulation in Cystinosis

* 80-EI-0093:
Visual Motor Coordination in Man

Active Follow-up, Protocols NOT Recruiting New Patients 

* 04-EI-0223:
Efficacy of Elevated CD4 Cell Counts on CMV Retinitis

* 04-EI-0013:
Pilot Study of Intravitreal Injection of Triamcinolone Acetonide Formulation for Retinal Vascular Disorders

* 03-EI-0291:
A Pilot Study of Laser Photocoagulation for Diabetic Macular Edema

* 03-EI-0101:
Pilot Study of Intravitreal Injection of EYE001 (Anti-VEGF Pegylated Aptamer) for Advanced Ocular Disease of Von Hippel-Lindau (VHL) Disease

* 02-EI-0257:
Multi-Center Randomized Phase I/II Trial to Study the Effects of Cyclooxygenase-2 Inhibition on the response to Photodynamic Therapy in Patients with Age-Related Macular Degeneration

* 02-EI-0242:
Evaluation of Subcutaneous Daclizumab Treatments in Patients with Non-infectious Sight-threatening Uveitis: A Multicenter, Open-Label, Phase II Study

* 01-EI-0208:
Feasibility Study of the Identification and Treatment of Feeder-Vessels of Choroidal Neovascularization in Age-Related Macular Degeneration

* 96-EI-0096:
Trial of Treatment of Non-Infectious Intermediate and Posterior Uveitis with Humanized Anti-Tac Antibody Therapy

* 92-EI-0250:
Age-Related Eye Disease Study - Phase II

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