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Clinical Research Resources Directory

Human Tissue and Organ Resources for Research

 
National Disease Research Interchange
National Disease Research Interchange (NDRI)
8 Penn Center
1628 JF Kennedy Boulevard, 8th Floor
Philadelphia, PA 19103

URL: www.ndriresource.org

Grant No. U42 RR06042
For information about this service and how to access its resources, please contact:

Principal Investigator/Research Director
John T. Lonsdale, Ph.D.
800-222-6374 x 271 or 215-557-7361 x 228; Fax: 215-557-7154
E-mail: jlonsdale@ndriresource.org

Background

NDRI is a nonprofit organization that procures and distributes normal and diseased human tissues for laboratory research studies to investigators in academia, government, and industry. Tissue donation provides an opportunity for people who wish to become organ donors, but whose tissues cannot qualify for transplantation and might otherwise be discarded. Studies with human tissue also serve as alternatives to the use of live animals in research.

Application for Services

NDRI tissue sources include hospitals, eye and tissue banks, and organ procurement organizations. Services are customized to the needs of each individual research program. Researchers who wish to receive tissue must complete an application form. Requested tissue specifications may include age, sex, race, aspects of medical history, sample size, post mortem or shipment time constraints, and other handling and processing parameters. Recipients of tissue are required to acknowledge NDRI as the tissue source in resultant publications. The NDRI bibliography of such publications is available upon request.

Review of Applications

Applications are reviewed for feasibility by a scientific Feasibility Review Committee and NDRI staff. All approved researchers agree to use tissue obtained through NDRI for laboratory research purposes only and not to resell or redistribute tissue. Approved researchers are entered into a queue for the appropriate tissue. Each researcher is served in turn when his/her requested tissue becomes available. Investigators stipulate the frequency and quantity of tissue they wish to receive, but may ask NDRI to interrupt shipments temporarily.

Quality Control

NDRI makes every effort to retrieve, process, and deliver biomaterials as requested by investigators and consistent with their intended use. The quality of samples is closely monitored from the time of procurement from the tissue source through packing, shipment, and delivery. Each shipment is accompanied by a request for information about shipment quality. This information is tracked to maintain quality service and investigator satisfaction.
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