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The Division of Comparative Medicine (DCM) utilizes a variety of National Institutes
of Health (NIH) funding mechanisms to support biomedical research. These grants,
in turn, ensure that the biomedical research community has access to specialized
facilities that provide mammalian and nonmammalian animal models. The DCM supports
research through the following grant mechanisms:
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(R01) Investigator-initiated Research Project Grants support basic research
projects related to laboratory animal science, medicine, and model systems related
to animal research that do not fall within the categorical interest of a single
Institute or Center (IC) of the National Institutes of Health (NIH).
Such projects should be designed to establish, expand, or improve the usefulness
of a particular model system. Grants may be awarded for investigations, including
pilot studies, to demonstrate the value of a certain animal species, stock, or
strain as a research model for naturally-occurring disease processes or other
biologic phenomena related to human health.
The research should be in an investigators area of interest and competency.
Refer to the Division of Comparative Medicine Program Guidelines for information
on application preparation and review criteria. Applicants must use the PHS Form
398. The application is expected to include preliminary data that supports the
proposed project.
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(R21) Exploratory/Development Grants support innovative, exploratory/developmental
research. The primary use of the R21 mechanism is to help applicants
acquire preliminary data in specific subject areas for use in preparing R01 or
R24 applications.
Unless specified otherwise through an announcement, review criteria are the same
as those for R01 grants. Originality of the approach and potential significance
of the proposed research are major considerations in the evaluation. The applicant
is responsible for developing a sound research plan. Applications for R21 awards
are accepted only in response to requests that specify this mechanism or after
consultation and agreement with NCRR program staff. These funds are not to be
used to supplement or supplant projects currently supported by Federal or non-Federal
funds, nor to provide interim support for projects under review.
Although these grants provide support for up to two years, they are not renewable.
Furthermore, they are expected to provide the opportunity to collect sufficient
preliminary data to apply for future support from either the NCRR or other NIH
ICs. Applications should be prepared in accordance with PHS Form 398 instructions.
Page and appendix limitations beyond those stated in the PHS 398 may apply, depending
on the specific announcement. For detailed information, including application
requirements, refer to the Division of Comparative Medicine Program Guidelines.
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(R13) Scientific Conference Grants support national and international meetings
sponsored and directed by the R13 grantees. Such meetings must be relevant to
the goals of the NCRR DCM. To ensure DCMs interest in the proposed meeting,
prospective grantees must contact DCM before submitting an application for funding.
If DCM determines a sufficient need to have substantial involvement in the planning
and conduct of the scientific meeting, then a cooperative agreement (U13) instead
of an R13 would be an appropriate award. Submission deadlines are February 1,
June 1, and October 1 of each year. For detailed information, including application
requirements, refer to the Division of Comparative Medicine Program Guidelines.
Applications should be prepared in accordance with PHS Form 398 instructions.
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(R15) Academic Research Enhancement Award (AREA) is an NIH effort to stimulate
research in educational institutions that provide baccalaureate training for a
significant number of our nations research scientists but have not been
major recipients of NIH support. NCRR participates in the AREA grant program to
support small-scale resource-related research projects proposed by faculty members
of eligible institutions. AREA grants are awarded on a competitive basis. Funding
decisions on individual applications will be based on scientific merit, relevance
to NCRR programs, and on the applicant institution's contribution to the undergraduate
preparation of doctoral-level health professionals. Applications should be prepared
in accordance with PHS Form 398 instructions. Application information, including
review considerations and award criteria, is available in the NIH Program Announcement:
PA-99-062.
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(R24) Resource-Related Research Grants predominantly support research
to develop new resources or to improve existing ones. Resources are defined
as animal, cell culture, or computer/mathematical models that have the potential
for becoming well-used systems for research projects. These grants are intended
to support research projects contributing to the knowledge of a model system that
will make the model more useful and more accessible to the research community.
For detailed information, including application requirements, refer to the Division
of Comparative Medicine Program Guidelines. Applications should be prepared in
accordance with PHS Form 398 instructions.
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For further information, contact:
Director, Division of Comparative Medicine
National Center for Research Resources
National Institutes of Health
One Democracy Plaza, Room 948
6701 Democracy Boulevard, MSC 4874
Bethesda, Maryland 20892-4874
Telephone: 301-435-0744
FAX: 301-480-3819
e-mail: CMADIR@mail.nih.gov
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