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General Clinical Research Center, Room M 907
University of Alabama at Birmingham
625 South 19th Street
Birmingham, AL 35233-6909
URL:
http://gcrc.hs.uab.edu/
Grant No. M01 RR00032 |
For information
about this GCRC and how to access its resources, please
contact:
Administrative Manager
Lou Ann Faulkner, B.S.
205-934-4852; Fax: 205-975-6616
E-mail:
louann@uab.edu
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Program Director
Larry Moreland, M.D.
205-934-2130; Fax: 205-975-6616
E-mail:
larry.moreland@ccc.uab.edu
Principal Investigator
William B. Deal, M.D.
205-934-1111; Fax: 205-934-0333
E-mail: wdeal@uab.edu
Associate Program Director
J. Michael Kilby, M.D.
205-975-1937; Fax: 205-934-8490
E-mail: mkilby@uab.edu
Associate Program Director, Pediatrics
David W. Kimberlin, M.D.
205-934-5316; Fax: 205-934-8559
E-mail: dkimberlin@uab.edu
Nurse Manager
Patricia Wittig, R.N.C., M.P.H.
205-934-4857; Fax: 205-975-6616
E-mail:
pwittig@uabmc.edu
Informatics Core Medical Director
Jeroan J. Allison, M.D.
205-934-4007; Fax: 205-975-7782
E-mail:
jallison@uab.edu
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Laboratory Director
Jeffrey C. Edberg, Ph.D.
205-934-0894; Fax: 205-975-6616
E-mail:
jedberg@uab.edu
Research Subject Advocate
Penelope M. Jester, M.P.H., B.S.N., C.C.R.C.
205-934-7619
E-mail: pjester@uabmc.edu
Physiology and Metabolic Core Director
Barbara A. Gower, Ph.D.
205-934-4087; Fax: 205-934-7049
E-mail: bgower@uab.edu
Bionutrition Research Manager
Betty E. Darnell, M.S., R.D.
205-934-4857; Fax: 205-975-6616
E-mail:
bdarnell@uab.edu
Biostatistician
Robert Oster, Ph.D.
205-934-3679; Fax: 205-934-4262
E-mail:
robert.oster@ccc.uab.edu
Computer Systems Manager
Michael Holland, M.C.S.A.
205-934-1381; Fax: 205-975-6616
E-mail:
mholland@uabmc.edu
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Special Resources, Instruments, or Services
Anthropometrics and dietary counseling
Computerized nutrient analysis with Minnesota Nutrition
Data System for Research
DNA immortalization
–70° Freezer
Glucose clamp technology
Infusion facilities
Intravenous glucose tolerance testing
Laminar flow hood
Metabolic research kitchen, metabolic diet planning,
outpatient and inpatient feeding
Molecular genetics core
Negative airflow isolation rooms
Physiology and metabolism core
SensorMedics Deltatracs
Specimen processing facility
Teleform preparation and management
Training Opportunities
Clinical investigator fellowship award
Nutrition fellowships for nutrition Ph.D. students
Nutrition traineeships for nutrition master's degree students
AIDS: NMR imaging for effects of protease
inhibitors on intramuscular lipids in HIV and cognitive/motor complex;
nutrition and physical activity in HIV; AIDS Clinical Trial Group
phase I and II studies.
Cardiology: Effect of dietary lipids on chylomicrons; bypass
angioplasty revascularization investigation in type 2 diabetes study;
identification of polymorphisms associated with low levels of plasma HDL;
nitric oxide and cardiovascular reactivity; congestive heart failure and
exercise training; low-glycemic diet in hypercholesterolemia.
Endocrinology: Adrenal androgen excess in hyperandrogenic
oligo-ovulation; metabolic response to variations in dietary
composition; insulin resistance, dietary cholesterol, and cholesterol
concentration; impact of dietary fat hyperandrogenism and ethnic differences
in insulin sensitivity; phosphorylation of insulin receptor in skin
and adipose tissue; diabetes mellitus in polycystic ovary syndrome;
obesity treatment in non-insulin-dependent diabetes mellitus.
Geriatric Medicine: Genetic and environmental factors in immunity
in aging; primary care patient services; muscle plasticity with resistance
training in older adults.
Hematology: Sickle cell disease; hemochromatosis;
phase I/II pharmacokinetics in liver transplant recipients.
Immunology: Biological definition of host defense
defects.
Infectious Diseases: Perinatal infections, symptomatic congenital
cytomegalovirus (CMV) infections; neonatal herpes simplex infections;
invasive fungal infections; treatment of neonates with enteroviral
sepsis syndrome; vaccine trial for CMV infection; antiviral treatment
for hearing loss in CMV infection; herpes simplex encephalitis and
valacyclovir.
Nephrology: Osteonecrosis in renal transplants; loss of kidney
function in sickle cell disease, polycystic kidney disease;
genetic polymorphisms in Wegener's granulomatosis; familial IgA
nephropathy; allograft nephropathy in pediatric renal transplant.
Nutrition: Energy expenditure in post-obese black and white women;
intra-abdominal fat and risk of disease in children and adolescents; energy
expenditure and body composition in pubescent females; exercise training
in obesity; weight management among spinal-cord-injured population; eating
behavior in homebound older adults; energy metabolism and body composition in
spinal cord disorder.
Oncology: Prostate cancer; non-small-cell lung cancer;
T cell malignancies; brain tumors; ovarian cancer; B cell lymphoma; metastatic
breast cancer; advanced carcinoma; colorectal cancer; advanced squamous cell
carcinoma of the head and neck; metastatic carcinoembryonic antigen
(CEA)-expressing adenocarcinoma; malignant mesothelioma; surgically incurable
melanoma; solid tumors; non-Hodgkin's lymphoma; Hodgkin's disease; astrocytoma;
glioblastoma multiforme; AIDS-associated non-Hodgkin's lymphoma; lymphocytic
leukemia; metastatic renal cell carcinoma; malignant gliomas.
Pulmonary Medicine: Mycoplasma infection in children with asthma;
scleroderma lung study; studies in cystic fibrosis.
Rheumatology: Pain perception and responses in fibromyalgia; outcome
of systemic lupus erythematosus (SLE) in minorities; central factors in
etiopathogenesis of fibromyalgia; genetics of SLE; periodontal disease and
rheumatoid arthritis; modifiable risk factors for adverse outcomes in SLE;
genetic risk factors for infection in SLE; longitudinal evaluation of
African Americans with rheumatoid arthritis; pneumococcal vaccine in
rheumatoid arthritis.
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