 |
|
|
|
|
|
General Clinical Research Center
Medical University of South Carolina
96 Jonathan Lucas Street
P.O. Box 250609
Charleston, SC 29425
URL:
www.gcrc.musc.edu/
Grant No. M01 RR01070
|
For information
about this GCRC and how to access its resources, please
contact:
Administrative Director
Vickie Wickman, B.S.N., M.B.A.
843-792-3257; Fax: 843-792-2601
E-mail:
wickmanv@musc.edu
|
|
|
|
Program Director
Peter W. F. Wilson, M.D.
843-792-6245; Fax: 843-792-2601
E-mail: wilsonpw@musc.edu
Principal Investigator
Joseph Gerald Reves, M.D.
843-792-2842; Fax: 843-792-2967
E-mail:
revesj@musc.edu
Associate Program Director
L. Lyndon Key Jr., M.D.
843-792-6807; Fax: 843-792-0548
E-mail:
key1@musc.edu
Associate Program Director
Kathleen Brady, M.D., Ph.D.
843-792-5205; Fax: 843-792-2601
E-mail:
bradyk@musc.edu
Research Subject Advocate
Melissa Henshaw, M.D., M.S.
843-953-8501; Fax: 843-792-2601
E-mail:
henshawm@musc.edu
|
Nurse Manager
Patricia Fuseler, R.N.
843-792-3356
E-mail:
fuselerp@musc.edu
Research Dietitian
Kelly Martin, M.P.H., R.D.
843-792-3357
E-mail:
martink@musc.edu
Biostatistician
Robert F. Woolson, Ph.D.
843-876-1135; Fax: 843-72-2601
E-mail:
woolson@musc.edu
Informatics Manager
James Bruce, M.S.
843-792-3256; Fax: 843-792-2601
E-mail:
brucej@musc.edu
|
|
Special Resources, Instruments, or Services
Anthropometrics, computerized diet analysis, dietary counseling
Bone densitometry (infant and adult)
Cardiac monitoring, echocardiography, oximetry
Class 10,000 clean room for cell isolation and transplant
Intravenous glucose tolerance testing, clamp studies
Metabolic kitchen
Molecular core laboratory
Whole-body calorimeter
Cardiovascular Diseases: Left ventricular myocardial
remodeling after myocardial infarction; optimal treatment of
hypertension; mediators of vascular responses; heart failure;
effects of obesity and fatty acids; neurogenic and volume
mechanisms in treatment-resistant hypertension; stroke
prevention in sickle cell disease.
Diabetes: Epidemiology of diabetes intervention and
complications; mechanisms of human insulin resistance;
heredity and insulin sensitivity; genetics of
non-insulin-dependent diabetes mellitus in African
Americans; characteristics and genetics of atypical
diabetes; pancreas transplant; impaired glucose tolerance;
glyco-oxidation and diabetic retinopathy; computer-based
diabetes education.
Endocrinology: Genetics, pathophysiology, and
treatment of osteopetrosis and other disorders of calcium
and vitamin D metabolism in infants, children, and adults;
hormonal regulation of bone and mineral metabolism; racial
differences in bone mineral metabolism and bone density;
familial characteristics of osteoporosis; obesity in
children and adults; effects of growth hormone in various
pathophysiologies.
Hematology and Oncology: Sickle cell disease and
thalassemia in children and adults; leukemias and
lymphomas; effects of metabolism, nutrition, and obesity in
cancer; optimal treatment for malignant neoplastic
diseases; pharmacokinetics, safety, and efficacy of new
pharmaceutical agents; reduced folate metabolites of
leukovorin.
Nephrology: Kidney disease secondary to hypertension
in African Americans; kidney transplant and acute
rejection.
Neurology: Multiple sclerosis; Duchenne muscular dystrophy.
Obstetrics and Gynecology: Preeclampsia; pelvic
inflammatory disease.
Pharmacology: Mediators and optimal treatment of
hypertension; metabolism of pharmaceuticals in humans; effects of herbs.
Psychiatry: Pathophysiology and treatment of anxiety, mood,
and obsessive-compulsive disorders in children and adults; treatment
of alcoholism, Tourette’s syndrome in children and adults; eosinophilia
myalgia syndrome; post-traumatic stress disorder; addictive disorders
such as nicotine and cocaine dependence; sleep and stimulation therapy.
Pulmonary Medicine: Pathogenesis of scleroderma
pulmonary disease.
Rheumatology: Detection, characterization, and
treatment of connective tissue diseases; Raynaud's disease;
eosinophilia myalgia syndrome.
|
 |
|
