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Acitretin in Treating Patients With Skin Disease or Skin Cancer
This study is no longer recruiting patients.
Sponsored by: | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
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Information provided by: | National Cancer Institute (NCI) |
Purpose
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Acitretin may be an effective treatment for skin disease and skin cancer. PURPOSE: Phase II trial to study the effectiveness of acitretin in treating patients who have skin disease or skin cancer.
Condition | Treatment or Intervention | Phase |
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actinic keratosis stage III mycosis fungoides/Sezary syndrome stage IV mycosis fungoides/Sezary syndrome skin metastases squamous cell carcinoma of the skin stage I mycosis fungoides/Sezary syndrome stage II mycosis fungoides/Sezary syndrome basal cell carcinoma of the skin |
Drug: acitretin |
Phase II |
MedlinePlus related topics: Lymphoma; Skin Cancer; Skin Diseases
Study Type: Interventional
Study Design: Treatment
Official Title: Phase II Study of Acitretin in Patients With Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas, or other Retinoid-Responsive Diseases or Malignancies
Study start: December 2001
OBJECTIVES: I. Determine the long-term safety and efficacy of acitretin in patients with psoriasis, cutaneous disorders of keratinization, multiple basal cell carcinomas, or other retinoid-responsive diseases or malignancies.
PROTOCOL OUTLINE: Patients receive oral acitretin daily in the absence of disease progression or unacceptable toxicity.
PROJECTED ACCRUAL: A total of 130 patients will be accrued for this study.
Eligibility
Criteria
PROTOCOL ENTRY CRITERIA:
--Disease Characteristics--
--Prior/Concurrent Therapy--
--Patient Characteristics--
Location Information
More Information
Clinical trial summary from the National Cancer Institute's PDQ® database
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