Protocol Number: 82-H-0032

Title:

Comprehensive Evaluation of the Etiology and Pathogenesis of Chronic Lung Disease (Screening Protocol)

Number:

82-H-0032

Summary:

Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood. This includes abnormalities in the airways, lungs, blood vessels in and around the lungs, and the tissue covering the lungs (pleura).

The purpose of this research study is to evaluate patients referred to the Pulmonary-Critical Care Medicine Branch (P-CCMB) of the National Heart, Lung, and Blood Institute (NHLBI) in order to;

1. Develop a better understanding of the causes and disease processes involved in disorders of the lungs

2. Identify patients eligible to participate in other P-CCMB research studies

Sponsoring Institute:

National Heart, Lung and Blood Institute (NHLBI)

Recruitment Detail

Type: Active Accrual Of New Subjects

Gender: Male & Female

Referral Letter Required: Yes

Population Exclusion(s): None

Eligibility Criteria:

INCLUSION CRITERIA:

Symptoms consistent with pulmonary disease.

May have family history of lung disease.

Patients with diseases of organs with know association with lung disease.

EXCLUSION CRITERIA:

Persons with no clinical evidence of lung disease.

Special Instructions:

This protocol includes an optional bronchoscopy.

Keywords:

Lavage

Bronchoscopy

Computed Tomography

Fiberoptic Bronchoscopy

Pulmonary Function Testing

Cardiopulmonary Exercise Testing

Allergen Skin Testing

Recruitment Keywords:

Chronic Lung Disease

Conditions:

Lung Disease

Investigational Drug(s):

None

Investigational Device(s):

None

Contacts:

Patient Recruitment and Public Liaison Office
Building 61
10 Cloister Court
Bethesda, Maryland 20892-4754
Toll Free: 1-800-411-1222
TTY: 301-594-9774 (local),1-866-411-1010 (toll free)
Fax: 301-480-9793

Electronic Mail:prpl@mail.cc.nih.gov

Citations:

Morphologic-physiologic correlates of the severity of fibrosis and degree of cellularity in idiopathic pulmonary fibrosis

Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage

Interstitial lung disease: current concept of pathogenesis, staging and therapy

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department of Networks and Applications, CC.

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Warren Grant Magnuson Clinical Center (CC)
National Institutes of Health (NIH)
Bethesda, Maryland 20892. Last update: 10/16/2004