Protocol Number: 97-C-0147

Title:

Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Disease

Number:

97-C-0147

Summary:

Selected patients suspected of having or with prior biopsy proof of malignant disease will be seen in the Urologic Oncology Branch, NCI. Blood samples may be collected at the time of the initial visit and at periodic intervals during the course of the disease. These samples will be stored in the tissue bank of the Urologic Oncology Branch. Aliquots of malignant and normal tissue will be collected at the time of surgery and stored in the tissue bank, Urologic Oncology Branch, NCI. These materials will be used in the research efforts of the Urologic Oncology Branch, NCI.

Sponsoring Institute:

National Cancer Institute (NCI)

Recruitment Detail

Type: Active Accrual Of New Subjects

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria:

INCLUSION CRITERIA:

Patients suspected of having, or with biopsy proof of malignant disease are eligible.

Patients must be able to provide informed consent.

Special Instructions: Currently Not Provided

Keywords:

Tissue Procurement

Recruitment Keywords:

None

Conditions:

Neoplasm

Investigational Drug(s):

None

Investigational Device(s):

None

Contacts:

CSSC
Clinical Studies Support Center/NCI
164 Rollins Avenue
2nd FLoor
Rockville, MD 20852
Phone: (888) 624-1937
Fax: (301) 881-8239

Electronic Address: ncicssc@mail.nih.gov

Citations:

Assessment of growth-limiting events caused by 5-fluorouracil in mouse cells in human cells

Time-dose relationships for 5-fluorouracil cytotoxicity against human epithelial cancer cells in vitro

Novel mechanisms of resistance to 5-fluorouacil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules

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Warren Grant Magnuson Clinical Center (CC)
National Institutes of Health (NIH)
Bethesda, Maryland 20892. Last update: 10/23/2004