Protocol Number: 01-N-0181

Title:

Language Stimuli Screening in Children

Number:

01-N-0181

Summary:

This study will determine baseline language skills in children 4 to 8 years old. The data will be used to design studies using functional magnetic resonance imaging (fMRI) to identify what areas of the brain in children are involved in understanding language. This information is important for children who require brain surgery to control seizures.

Healthy normal volunteers between the ages of 4 and 8 years who have an IQ of 70 or more; who have no history of neurologic, psychiatric or language disorder; who are performing at or above grade level, and who are native English speakers may be eligible for this study.

Participants will be asked to do the following:

- name pictures or read words that appear on a computer screen

- listen to stories and answer questions about them

- match pictures to a spoken word

The children's responses will be recorded.

Sponsoring Institute:

National Institute of Neurological Disorders and Stroke (NINDS)

Recruitment Detail

Type: Active Accrual Of New Subjects

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria:

INCLUSION CRITERIA:

Children will be between the ages 4 and 8 are eligible.

EXCLUSION CRITERIA:

Children who meet one of the following criteria are not eligible:

IQ below 70;

History of neurologic or psychiatric disorders;

History of an language disorder;

Performing below grade-level;

Non-native English speaker.

Special Instructions: Currently Not Provided

Keywords:

Reading

Naming

Recruitment Keywords:

None

Conditions:

Language Disorder

Healthy

Investigational Drug(s):

None

Investigational Device(s):

None

Contacts:

Patient Recruitment and Public Liaison Office
Building 61
10 Cloister Court
Bethesda, Maryland 20892-4754
Toll Free: 1-800-411-1222
TTY: 301-594-9774 (local),1-866-411-1010 (toll free)
Fax: 301-480-9793

Electronic Mail:prpl@mail.cc.nih.gov

Citations:

Noninvasive assessment of language dominance in children and adolescents with functional MRI: a preliminary study

Anterior temporal language areas in patients with early onset of temporal lobe epilepsy

Picture naming by young children: norms for name agreement, familiarity, and visual complexity

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department of Networks and Applications, CC.

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Warren Grant Magnuson Clinical Center (CC)
National Institutes of Health (NIH)
Bethesda, Maryland 20892. Last update: 10/23/2004