| Agent Name |
Pyrogallol |
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| CAS Number |
87-66-1 |
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| Formula |
C6-H6-O3 |
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| Major Category |
Other Chemicals |
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| Synonyms |
Benzene, 1,2,3-trihydroxy-; 1,2,3-Benzenetriol; CI Oxidation Base 32; CI 76515; Fouramine Brown AP; Fourrine 85; Fourrine PG; Pyro; 1,2,3-Trihydroxybenzene; [HSDB] |
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| Category |
Phenols |
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| Description |
Odorless, white to gray solid; |
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| Sources/Uses |
Used in photography and leather crafts; used in wool, fur, and hair dyeing; also used as an analytical chemistry reagent, an antioxidant for oils, and as a topical medication; [HSDB] Used in hair dyes and was used in photographic developers; [Kanerva, p. 1170] No longer used in hair dyes because of the frequency of allergic reactions; [Kanerva, p. 966] |
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| Comments |
Reported human toxicity after ingestion includes methemoglobinemia, hemolysis of red blood cells, and damage to the liver and kidneys. [HSDB] A potential skin sensitizer; [ICSC] Allergic contact dermatitis reported in hairdressers; [Kanerva, p. 1170] |
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| Reference Link |
Allergic reactions to a hairdressers' series: results from 9 European centres. The European Environmental and Contact Dermatitis Research Group (EECDRG) |
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| Exposure Assessment |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PYROGALLIC ACID
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