NIDDK Recent Advances and Emerging Opportunities (2002) The following documents are in Adobe Acrobat PDF format. You must have Adobe Acrobat Reader installed on your computer to view them. To download Adobe Acrobat Reader, go to the Adobe Acrobat Reader download site.

• Functional Genomics: Tools for Discovering the Functions of Genes Relevant to Disease
• Modeling the Control of Cell Growth Through Mice
         Cell Growth and DNA Damage in Breast Cancer
         Multiple Endocrine Neoplasia
  
• Unfolding Protein Folding
         Prions and Amyloids in a Yeast Model System
         Protein Folding in Amyloid Disease-Implications for Therapy
  
• "Insights" into the Digestive System-Feeding Fluorescent Fats to Zebrafish
• Using a Genetic Database To Prevent Blood Transfusion Reactions
• Taking Tools into the Future-Building Knowledge of Disease Genes
         Modifier Genes
         Increasing Understanding of Membrane Transport
         Beta Cell Biology Consortium
         Progenitor Cell Genome Anatomy Projects (GAPS)
  
• Stem Cells: Developing Potential

• Cell Signals and the Development of Type 2 Diabetes: Insights from Animal Models
• Mechanisms of Insulin Resistance
• Control of Glucose Production
• Effects of Appetite-Controlling Hormone Leptin
• Stress Hormone May Determine Fat Deposition that Promotes Diabetes
• Preventing Type 2 Diabetes and Its Complications
• Impressive Clinical Trial Results Transform Hope into Reality
          Lifestyle Interventions Have Enormous Benefits
          Translating Message of the Diabetes Prevention Program
          Post-DPP Study
• Cardiovascular Complications
• Diabetes in Pregnancy
• Improved Long-Term Survival for Patients with Type 1 Diabetes
• Beta Cells That Resist Destruction by the Immune System-
• Implications for Type 1 Diabetes
• Type 1 Diabetes TrialNet
• Translating Diabetes Information into Intervention
• Inborn Errors of Metabolism
• Hormonal Regulation of Bone Loss
• Highly Active Antiretroviral Therapy for HIV Infection-Benefits and Drawbacks
• Increased Risk of Cardiovascular Disease in HIV-Positive Patients with Fat Redistribution Associated with Antiretroviral Therapy
• Effect of the Protease Inhibitor Indinavir on Import of Glucose into Muscle
• Protease Inhibitors Impair Fat Cell Development
• Benefits of Antiretroviral Therapy in HIV-Positive Children
• NIDDK and NIH Research Efforts
• Getting the Message Out: The National Diabetes Education Program (NDEP) (pdf-36kb)
• Diabetes Research and Training Centers-Making a Difference in Diabetes Care (pdf-84kb)
• Story of Discovery: The Ominous Link Between Obesity and Type 2 Diabetes (pdf-48kb)
• Patient Profile: Sigrun Schwendinger-Islet Transplantation Holds Great Hope for Type 1 Diabetes Patients (pdf-144kb)

• Obesity: A National Health Problem
• Prevention Message of Type 2 Diabetes Trial
• The Diabetes Prevention Program (DPP)
• The Biology of Obesity
• Tipping the (Molecular) Scales
          Imbalances in Hormonal Signals
          Enhancing Calorie-Burning
• Role of Genetics and the Environment
• NIDDK Efforts
• Copper Transport
• Insights from Yeast
• Chaperone Proteins
• Hereditary Pancreatitis
• Irritable Bowel Syndrome: Altered Neurological Activity
• Hepatitis C
• New Clinical Trial To Address Resistance to Current Treatments
• HALT-C Clinical Trial
• Who Should Lose Weight? (pdf-48kb)
• Story of Discovery: Genetic Breakthroughs in the Study of Crohn's Disease (pdf-36kb)
• Patient Profile: Rima Matsumoto-Nonalcoholic Steatohepatitis (NASH) (pdf-60kb)

• Genetic Link Discovered for IgA Nephropathy
• Genes and Technology Spur Advances in Polycystic Kidney Disease (PKD)
• Functions of PKD Genes
• Use of Computer Tomography Scans To Track PKD
• Facilitating PKD Research
• Kidney Disease and Diabetes
• Preventing Kidney Failure
• African American Study of Kidney Disease and Hypertensio
n
• Cohort Study of Chronic Renal Insufficiency
• National Kidney Disease Education Program
• Understanding the Function, Structure, and Genetics of the Urinary Bladder
• Protecting the Bladder's Permeability Barrier
• Dynamic Role of Bladder in Releasing Proteins into the Urine
• Bladder Cancer Diagnosed by Simple Urine Test
• Urinary Tract Infections: Insights into Causes and Treatments
• Asymptomatic UTIs
• Recurrent UTIs
• Antibiotic Resistance
• Prostate Disease: New Clinical Efforts
• Developing Biologic Markers and Genetic Tests
• Assessing New, "Minimally Invasive" Surgical Treatments
• Chronic Prostatitis Collaborative Research Network
• Stem Cell Approaches for Blood Disorders
• Allogeneic Bone Marrow Transplantation
• Autologous Stem Cell Gene Therapy Approaches
• National Kidney Disease Education Program (NKDEP) (pdf-24kb)
• Story of Discovery: Bacterial Pili-Molecular Initiators of Bladder and Kidney Infections (pdf-48kb)
• Patient Profile: Art and Pat Joseph-New Immunosuppressant Approaches to Kidney Transplantation (pdf-144k)

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