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ABCC Applications Web Page
Welcome to the ABCC Accessible Application Web Page.
From this page, you can get information about our scientific applications and databases. To get more information about any topic, or to run an application, click on any of the mouseover popup menu items on the left-hand side. Program with a tag "Run" is runnable. This site continues to grow, so come back often to check out the many accessible applications available here at the Advanced Biomedical Computing Center (ABCC).
If you have any comments or suggestions, please contact us Help link
Protein Analysis
ASSP
ASSP is a program to predict the expected best accuracy for a
secondary structure prediction based on a multiple sequence
alignment.
Website: Click Here
Core-find
The core-find package is a collection of tools that facilitates
calculation and analysis of the cores of families of structurally
similar proteins.
Website: Click Here
SeqSpace
Sequence Space implements a method of clustering aligned protein
sequences based upon the algorithm developed by G. Casari, C. Sander
and A. Valencia. Full details of the method can be found in the
paper: A method to predict functional residues in proteins, Georg
Casari, Chris Sander and Alfonso Valencia. Structural Biology volume
2, no. 2, February 1995.
Each sequence is converted into a vector in "Sequence Space",
projection of which onto a lower dimensional space allows 2- or
3-dimensional viewing of the resulting clusters.
By projecting the sequence residues into the same space, groups of
residues specific for the clusters are revealed, allowing the
identification of residues that are predicted to be directly
involved in protein function.
There are two programs available, the main sequence space program
and a set of Java viewers combining sequence space views
with more conventional protein displays.
Website: Click Here
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