Human SAGE Genie Tools

• SAV
• DGED
• SEV
• SALL
• Library Finder
• Downloads

Mouse SAGE Genie Tools

• mDGED
• mSALL
• mDigital Northern
• mLibrary Finder
• mDownloads

Related Links

• Ludwig Institute for Cancer Research
  
• SAGEmap xProfiler
  
• SAGEmap vNorthern
  
• SAGE (JHU)
  
  

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SAGE Genie

SAGE Genie

Serial Analysis of Gene Expression (SAGE) is a method to efficiently count large numbers of mRNA transcripts by sequencing short tags, usually 10 or 17 bp in length. SAGE Genie (Boon et al.) uses a new analytical method of reliably matching SAGE tags to known genes. Based on this novel tag to gene mapping, the website visualizes human and mouse gene expression analysis in tissues or individual libraries using displays that are highly intuitive.

Need help?	•	If this is your first time using SAGE Genie and you need help using the tools, please visit SAGE Genie Help.
	•	For a brief description of SAGE and SAGE Genie, please read SAGE Information.
	•	For SAGE and SAGE Genie references, please see References

Human SAGE Genie Tools

• The SAGE Anatomic Viewer visually displays the relative expression of a given gene in normal and malignant tissues of the human body. In addition, there is access to:
  • The Digital Northern, which shows the relative expression of the gene in each library.
  • The Ludwig Transcript (LT) Viewer, which visually represents a particular transcript with four possible virtual SAGE tag locations (starting from the 3' end) and locations of internally primed or alternatively polyadenylated transcripts.
• The SAGE Digital Gene Expression Displayer distinguishes significant differences in gene expression profiles between two pools of SAGE libraries.
• The SAGE Experimental Viewer provides DGED results for pre-set pairs of libraries, one under control and the other under experimental conditions.
• The SAGE Absolute Level Lister lists all SAGE libraries and links to the distribution of transcript expression levels in any given library.
• The SAGE Library Finder tool searches for one or more tissue-specific libraries from the SAGE collection.
• SAGE Genie Downloads provide files of genes, tags, datasets, mappings, and more.

Mouse SAGE Genie Tools

• The mSAGE Absolute Level Lister lists all mouse SAGE libraries, organized by either tissue (normal or malignant) or developmental stage, and links to the distribution of transcript expression levels in any given library.
• The mSAGE Digital Gene Expression Displayer distinguishes significant differences in gene expression profiles between two pools of mouse SAGE libraries.
• The mSAGE Digital Northern shows the relative expression of a selected gene in each library in which it is found..
• The mSAGE Library Finder tool searches for one or more tissue-specific mouse libraries from the SAGE collection.
• mSAGE Genie Downloads provide files of mouse genes, tags, datasets, mappings, and more.

Note: The majority of human libraries are short whereas the majority of mouse libraries are "long".

SAGE Genie Collaborators

SAGE Genie was produced as part of the CGAP SAGE project by collaborators from Johns Hopkins University, Duke University, the Ludwig Institute for Cancer Research (Sao Paulo Branch), and the National Cancer Institute.