Preface
..............................................................................................................................
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ii |
| On
the Frontiers of Knowledge: 30 Years of Alcohol Research
......................................... |
1 |
|
Introduction ............................................................................................................ |
1 |
|
Magnitude of the Problem ....................................................................................... |
2 |
Accomplishing the Mission: Key NIAAA Functions ................................................
|
3 |
| NIAAA's
Vision: At the Threshold of the New Millennium, New Successes
................ |
4 |
|
Overview ........................................................................................................... |
4 |
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Goal 1: Identify Genes That are Involved in
Alcohol-Associated Disorders ............... |
5 |
Goal 2: Identify Mechanisms Associated With
Neuroadaptation at Multiple
Levels of Analysis (Molecular,
Cellular, Neural Circuits, and Behavior) ..................... |
6 |
|
Goal 3: Identify Additional Science-Based Preventive
Interventions ........................ |
8 |
Goal 4: Further Delineate Biological Mechanisms
Involved in the Biomedical
Consequences Associated
With Excessive Alcohol Consumption ......................... |
11 |
Goal 5: Discover New Medications to Diminish
Craving for Alcohol,
Reduce Likelihood of Posttreatment
Relapse, and Accelerate Recovery of Organ Function |
14 |
Goal 6: Advance Knowledge of the Influence
of Environment on Expression
of Genes Involved in Alcohol_Associated
Behavior, Including Vulnerable
Adolescent Years and in
Special Populations ..................................................... |
16 |
Goal 7: Further Elucidate the Relationships
Between Alcohol and Violence .........
|
18 |
| Implementation
of the Plan ................................................................................... |
22 |
|
NIAAA Core Strategies ..................................................................................... |
22 |
Key External Factors That Could Affect Achievement of the NIAAA's
Goals and Objectives ...................................................................................... |
23 |
|
Linking Mission and Performance Monitoring...................................................... |
23 |
Use of Evaluations and Assessments ................................................................
|
24 |
Drafting
the Plan ...................................................................................................
|
25 |
| Appendix:
Descriptions of Program Evaluations and Other Studies ..................... |
26 |
