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Insulin Resistance and Insulin Secretion
This study is currently recruiting patients.
Sponsored by: | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
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Information provided by: | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Purpose
This is a pilot study to examine the prevalence of metabolic risk factors (impaired insulin release and impaired insulin sensitivity) for type 2 diabetes mellitus in children and adults from a population that is at high risk for this disease. We hypothesize that at least one of these pre-diabetic traits will be evident in a large proportion of relatives of known type 2 diabetic children as compared to a control group of subjects without a family history of type 2 diabetes. By isolating these traits, it will be possible to determine the relative contributions of genes and environment to each trait and to identify those at risk for subsequent development of type 2 diabetes by virtue of having one trait. Ultimately, those individuals at risk, especially those with impaired insulin release, would hopefully benefit from intervention to prevent the weight gain that will 'unmask' their underlying pancreatic dysfunction and thus prevent or retard the development of type 2 diabetes.
Condition | Treatment or Intervention |
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Diabetes Mellitus, Type 2 |
Behavior: diet |
MedlinePlus related topics: Diabetes
Study Type: Interventional
Study Design: Prevention, Non-Randomized, Single Blind, Uncontrolled, Single Group Assignment, Bio-equivalence Study
Official Title: Phenotypic Assessment of Insulin Resistance and Insulin Secretory Capacity
Eligibility
Ages Eligible for Study: 10 Years - 20 Years, Genders Eligible for Study: Both
Criteria
Ascertainment criteria for probands:
Location and Contact Information
More Information
U.S. National Library of Medicine, Contact NLM Customer Service | ||||||||||||||
National Institutes of Health, Department of Health & Human Services | ||||||||||||||
Copyright, Privacy, Accessibility, Freedom of Information Act |