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Biological Specifications for Denture Designs
This study is currently recruiting patients.
Sponsored by: | Department of Veterans Affairs |
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Information provided by: | Department of Veterans Affairs |
Purpose
The primary term goal of these research efforts has been to enhance the functional status, comfort and quality of life of edentulous patients by evaluating clinical procedures, denture designs and adjunctive therapies based upon a clear understanding of: (1) oral functional impairments caused by the loss of teeth and subsequent tissue changes; (2) neurophysiological mechanisms associated with oral functions; (3) metabolism of oral tissues; and (4) interactions between biological and psychological processes and denture characteristics. The primary purpose of the proposed clinical outcome study is to compare the relative efficacies of three different combinations of implant-supported maxillary and mandibular prostheses with traditional complete dentures for edentulous patients. Completion of this study will determine the relative cost-effectiveness of the implant-supported denture treatments for use in the general population of edentulous patients.
Condition | Treatment or Intervention | Phase |
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Tooth Loss |
Procedure: Implant-supported denture |
Phase II |
MedlinePlus related topics: Gum Disease; Tooth Disorders
Study Type: Interventional
Study Design: Treatment, Non-Randomized, Open Label, Dose Comparison, Single Group Assignment, Efficacy Study
Study start: October 1999;
Study completion: September 2004
Eligibility
Ages Eligible for Study: 35 Years - 80 Years, Genders Eligible for Study: Both
Accepts Healthy Volunteers
Criteria
Inclusion criteria:
Completely edentulous veterans with clinically acceptable conventional dentures.
Both male and female applicants will be accepted and the prospective participants will be from 35 to 80 years of age.
Patients who have been completely edentulous for at least two years and have clinically acceptable conventional dentures, which have been worn for at least 6 months.
Exclusion criteria:
1. Verified history of medical conditions such as connective tissue disorders, blood dyscrasias, uncontrolled endocrine disorders, active tuberculosis, AIDS, leukemias, Hodgkins, liver disfunction, osteoporosis, chronic nephritis, any chronic condition with life expectancy of less than five years as well as patients on long-term steroids, anticoagulants, and radiation therapy.
2. Extremely poor oral hygiene. Oral hygiene condition will be assessed from the amount of food debris, plaque and calculus in their present dentures.
3. Insufficient mandibular or maxillary bone height to accommodate 10 mm long implants in potential implant sites.
4. Presence of temporomandibular joint dysfunction and evidence of severe bruxism.
5. Physician determines a contraindication for oral surgery.
6. Candidate expresses reservations about participating for at least three years.
Location and Contact Information
More Information
U.S. National Library of Medicine, Contact NLM Customer Service | ||||||||||||||
National Institutes of Health, Department of Health & Human Services | ||||||||||||||
Copyright, Privacy, Accessibility, Freedom of Information Act |