NHLBI Grants and Contracts

• Requests for Applications (RFAs)
• Requests for Proposals (RFPs):
  • National Heart, Lung, and Blood Institute
  • National Institute for Dental and Cranofacial Research
  • Center for Scientific Review
  • National Center for Research Resources
  • Office of Research Services
• RFP Archive
• Program Announcements (PAs)
• NIH Office of Extramural Research: Current News Flashes & Archives
• Security Policies, Forms and Procedures

Requests for Applications (RFAs)

Listed in numerical order by RFA number.

All NHLBI RFAs, including those whose application receipt date has passed and those of other ICDs, can be found on the Web page for the NIH Guide to Grants and Contracts, grants section, or by using the NIH Guide to Grants and Contracts Search Engine.

• RFA-NS-05-005: Centers of Excellence in Translational Human Stem Cell Research
  Receipt Dates: Letter of Intent, February 24, 2005
  Application, March 24, 2005
  
• RFA-HL-05-004: Novel Targets and Therapy Development for Ischemic Stroke
  Receipt Dates: Letter of Intent, December 10, 2004
  Application, January 11, 2005
  
  
• RFA-HL-05-001: Specialized Centers of Clinically Oriented Research (SCCOR) in Vascular Injury, Repair, and Remodeling
  Receipt Dates: Letter of Intent, April 11, 2005
  Application, May 11, 2005
  
  
• RFA-HL-04-022: Bioengineering Approaches to Energy Balance and Obesity
  Receipt Dates: Letter of Intent, January 17, 2005
  Application, February 16, 2005 
  
  
• NOT-HL-04-115: Notice Of Additional Receipt Date for the following RFAs:
  RFA-HL-03-014: Short-Term Training For Minority Students Program (T35) &
  RFA-HL-03-011: Mentored Minority Faculty Development Award (K01)
  Receipt Date, Application, August 26, 2004
  
  
• RFA-HL-04-036: Causes and Mechanisms of COPD Exacerbations
  Receipt Dates: Letter of Intent, December 13, 2004
  Application, January 11, 2005
  
  
• RFA-HL-04-034: Cellular And Genetic Discovery Toward Curative Therapy In Myeloproliferative Disorders (MPD)
  Receipt Dates: Letter of Intent, January 16, 2005
  Application, February 16, 2005
  
  
• RFA-HL-04-033: Myelodysplastic Syndrome (MDS): Seeking Cure Through Discovery On Pathogenesis And Disease Progression
  Receipt Dates: Letter of Intent, January 16, 2005
  Application, February 16, 2005
  
  
• RFA-HL-04-032: Improved Therapy for Hemophilia and Hereditary Bleeding Disorders
  Receipt Dates: Letter of Intent, December 15, 2004
  Application, January 14, 2005
  
  
• RFA-HL-04-031: Mechanisms of HIV-Related Pulmonary Complications
  Receipt Dates: Letter of Intent, February 17, 2005
  Application, March 16, 2005
  
  
• RFA-HL-04-027: Minority Institutional Research Training Program (T32)
  Receipt Dates: Letter of Intent, May 22, 2004; May 21, 2005; May 20, 2006
  Application, June 23, 2004; June 22, 2005; June 21, 2006
  
  
• RFA-HL-04-026: Mentored Career Award for Faculty at Minority Institutions (K01)
  Receipt Dates: Letter of Intent, May 22, 2004; May 21, 2005; and May 20, 2006
  Application, June 23, 2004; June 22, 2005; and June 21, 2006
  
  
• RFA-HL-04-023: Community-Responsive Interventions to Reduce Cardiovascular Risk in American Indians and Alaska Natives
  Receipt Dates: Letter of Intent, September 22, 2004
  Application, October 22, 2004
  
  
• RFA-HD-04-020: Prevention and Treatment of Childhood Obesity in Primary Care Settings
  Receipt Dates: Letter of Intent, October 25, 2004
  Application, November 23, 2004
  
  
• RFA-HL-04-019: NHLBI Clinical Proteomics Programs
  Receipt Dates: Letter of Intent, September 17, 2004
  Application, October 14, 2004
  
  
• RFA-HL-04-018: Specialized Centers Of Clinically Oriented Research (SCCOR) in Transfusion Biology And Medicine
  Receipt Dates: Letter of Intent, August 17,2004
  Application, September 21, 2004
  
  
• RFA-HL-04-017: Specialized Centers For Cell-Based Therapy (SCCT) For Heart, Lung, And Blood Diseases And Data And Coordinating Center (DCC)
  • Special Instructions for the Preparation of Grant Applications
  • Frequently Asked Questions
  • Pre-Submission Meetings (May 24 and June 3, 2004)
  Receipt Dates: Letter of Intent, August 21, 2004
  Application, September 21, 2004
  
  
• RFA-HL-04-016: Specialized Centers Of Clinically Oriented Research (SCCOR) in Hemostatic and Thrombotic Diseases
  Receipt Dates: Letter of Intent, August 24, 2004
  Application, September 21, 2004
  
  
• RFA-HL-04-012: Cultural Competence and Health Disparities Academic Award
  Receipt Dates: Letters of Intent, January 23, 2004; September 19, 2004; September 19, 2005
  Applications, February 23, 2004; October 19, 2004; October 19, 2005
  
  
• RFA-GM-04-002: Pharmacogenetics Research Network and Knowledge Base
  • NOT-GM-04-108 – Corrections and Updates
  Receipt Dates: Letter of Intent, July 19, 2004
  Application, August 19, 2004
  
  
• RFA-DK-03-018: Genetic Studies of Obesity-Related Traits in Model Organisms

  Addendum 1 (January 30, 2004)

  Addendum 2 (March 5, 2004)

  Receipt Dates: Letter of Intent, February 18, 2004 and February 17, 2005
  Application, March 17, 2004 and March 17, 2005
  
  

Requests for Proposals (RFPs)

Listed in numerical order by RFP number.

The NHLBI provides assistance in publishing RFPs to the National Institute of Dental and Craniofacial Research (NIDCR), the National Center for Research Resources (NCRR), the Center for Scientific Review (CSR), and the Office of Research Services (ORS).

RFPs whose proposal receipt date has passed can be found in the RFP Archives.

RFPs of other Institutes, Centers, and Divisions (ICDs) can be found on the NIH RFP Directory.

FedBizOps also lists these RFPs

NHLBI RFPs

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• NHLBI-HR-05-05: Clinical Coordinating Center for a Clinical Research Network for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome
  • Amendment 1
  • Amendment 2
  • Amendment 3
  • Amendment 4
  • Amendment 5
  Receipt Dates: Letter of Intent, August 27, 2004
  Proposal, October 15, 2004, 2:30 p.m. EST (as per Amendment 5)
  
  
• NHLBI-HR-05-04: Clinical Centers for a Clinical Research Network for the Treatment of Acute Lung Injury & Acute Respiratory Distress Syndrome
  • Amendment 1
  • Amendment 2
  • Amendment 3
  • Amendment 4
  Receipt Dates: Letter of Intent, August 27, 2004
  Proposal, October 15, 2004, 2:30 p.m. EST
(as per Amendment 4)

NIDCR RFPs

• Currently, there are no RFPs related to scientific programs that are accepting proposals.

NCRR RFPs

• Currently, there are no RFPs related to scientific programs that are accepting proposals.

CSR RFPs

• Currently, there are no RFPs related to scientific programs that are accepting proposals.

ORS RFPs

• Currently, there are no RFPs related to scientific programs that are accepting proposals.

Program Announcements (PAs)

Listed in numerical order by PA number.

All NHLBI PAs, including those whose application receipt date has passed and those of other ICDs, can be found on the Web page for the NIH Guide to Grants and Contracts, program announcements section, or by using the NIH Guide to Grants and Contracts Search Engine.

• PA-04-161: Manufacturing Processes Of Medical, Dental, and Biological Technologies (SBIR/STTR)
  (expires October 1, 2007)
• PA-04-156: Bioengineering Approaches to Energy Balance and Obesity (SBIR/STTR)
  (expires August 2, 2007)
• PAS-04-149: Genetics and Pathobiology of Vascular Cognitive Impairment
  (expires August 2, 2007)
• PA-04-145: School-Based Interventions to Prevent Obesity
  (expires November 2, 2007)
• PA-04-126: Supplements to Promote Reentry into Biomedical and Behavioral Research Careers
  (expires July 9, 2007)
• PA-04-125: Novel Approaches to Enhance Animal Stem Cell Research
  (expires November 2 2007)
• PA-04-121: Understanding Mechanisms of Health Risk Behavior Change in Children and Adolescents
  (expires March 1, 2007)
• PAR-04-116: Understanding and Promoting Health Literacy (R01)
  (expires October 14, 2006)
• PA-04-107: Midcareer Investigator Award in Patient-Oriented Research (K24)
  (expires April 1, 2007)
• PA-04-098: Heterogeneity of Fat Depots: Underlying Basis and Association with Morbidity
  (expires March 2, 2007)
• PA-04-093: Novel Approaches to Study Polymicrobial Diseases
  (expires July 2, 2007)
• PA-04-089: New Technology for Proteomics and Glycomics (SBIR/STTR)
  (expires April 2, 2007)
• PAR-04-083: Fogarty International Collaborative Trauma and Injury Research Training Program (ICTIRT)
  (expires April 1, 2007)
• PA-04-080: Pathogenesis of SARS Lung Disease: In Vitro Studies and Animal Models
  (expires March 2, 2007)
• PAR-04-077: Research Partnerships for Improving Functional Outcomes
  (expires October 16, 2006)
• PA-04-071: Pathogenesis and Treatment of Lymphedema and Lymphatic Diseases
  • Addendum: NOT-HL-04-111 (to correct contact addresses)
  (expires on December 31, 2006)
• PA-04-059: SBIR/STTR Technologies for Monitoring and Performing Resuscitation
  (expires on February 1, 2007)
• PA-04-038: Occupational Health and Safety Research (R01)
  (expires on November 23, 2006 )
• PAR-04-037: NHLBI Competitive Supplements for Human Embryonic Stem Cell Research
  (expires on February 13, 2004)
• PA-04-033: Diet Composition and Energy Balance
  (expires on November 2, 2006)
• PA-04-028: Competing Continuation Awards of SBIR Phase II Grants For Heart, Lung, Blood, and Sleep Disorders
  (expires on December 6, 2006)
• PAR-04-023: Bioengineering Research Partnerships
  (expires on August 22, 2006)
  
  
• PAR-03-176: NIH Support for Conferences and Scientific Meetings
  (expires on September 16, 2006)
• PAR-03-177 (Addendum ): Human Embryonic Stem Cell Research Resource Infrastructure Enhancement Award
  (expires on January 12, 2005)
• PA-03-171: Exploratory and Developmental Research Grants for Investigations In Rare Diseases (R21)
  (expires on Sept 02, 2006)
• PA-03-170: Health Promotion Among Racial and Ethnic Minority Males
  (expires on August 31, 2006)
• PA-03-159: Chronic Illness Self-Management in Children
  (expires on July 30, 2006)
• PAS-03-131: Sleep Disturbance in Parkinson's Disease and Parkinson-like Conditions
  (expires on September 30, 2006)
• PA-03-123 Development of Diagnostic Screening Test for Salt Sensitivity (SBIR/STTR)
  (expiers on April 30, 2006)
• PAR-03-119 Innovations in Biomedical Computational Science and Technology: SBIR/STTR Initiative
  (expires on November 26, 2005)
• PAR-03-118 Global Health Research Initiative Program for New Foreign Investigators
  • Addendum (NOT-TW-04-003) Expanding the Eligibility Criteria
  (expires on April 16, 2006)
• PAR-03-106 Innovations in Biomedical Computational Science and Technology
  (expires on February 24, 2006)
• PAR-03-089: Centers for AIDS Research: D-CFAR, CFAR
  (expires on June 17, 2005)
• PA-03-069: The Biological Basis of Hutchinson-Gilford Syndrome (HGS): Relationship to Mutations in the Lamin A/C Gene (LMNA) and to Other Known Laminopathies
  (expires on March 1, 2006)
• PAR-03-063: NHLBI Competitive Supplements for Human Embryonic Stem Cell Research
  (expires on April 25, 2003)
• PA-03-058: Exploratory/Developmental (R21) Bioengineering Research Grants (EBRG)
  • Amendment 1, NHLBI application deadline
  • Amendment 2 (supercedes Amendment 1) applications will again be accepted by NHLBI as of June 1, 2004
  (expires January 1, 2006)
• PA-03-057: Social and Demographic Studies of Race and Ethnicity in the United States
  (expires February 2006)
• PA-03-053: Academic Research Enhancement Award
  (expires January 2006)
• PA-03-049: Chemical Screens for New Inducers of Fetal Hemoglobin (SBIR/STTR)
  (expires December 1, 2005)
• PA-03-047: Research on Microbial Biofilms
  (expires December 2005)
• PAR-03-036: Innovative Exploratory Studies and Technology Development in Neuroinformatics Research (R21)
  (expires October 2005)
• PAR-03-035 The Human Brain Project (Neuroinformatics): Phase I - Feasibility; Phase II - Refinements, Maintenance and Integration
  (expires October 2005)
• PA-03-031: Systems and Methods for Small Animal Imaging (SBIR/STTR)
  (expires on November 1, 2005)
• PA-03-018: AIDS International Training and Research Program
  • Addendum (Revised Receipt Dates)
  • Addendum (Revised Receipt Dates)
  • Addendum (Revised Letter of Intent Dates)
  (expires on October 25, 2005)
• PA-03-015: NHLBI Innovative Research Grant Program
  (expires on October 01, 2006)
• PA-03-001: Knowledge Integration Across Distributed Heterogeneous Data Sources (SBIR/STTR)
  (expires on December 31, 2004)
  
  
• PA-02-165: Race/Ethnic Disparities in the Incidence of Diabetes Complications
  (expires on February 1, 2006)
• PA-02-159: Enhancing Adolescent Health Promotion Across Multiple High Risk Behaviors
  (expires on August 23, 2005)
• PAR-02-154: NHLBI Career Transition Award (K22)
  (expires on September 1, 2005)
• PA-02-147: Novel Approaches to Enhance Animal Stem Cell Research
  (expires on May 31, 2004)
• PAR-02-142: Tools for Genetic Studies in Zebrafish
  (expires on July 31, 2005)
• PA-02-127: Mentored Quantitative Research Career Development Award (supersedes PA-99-087)
  (expires on June 3, 2005)
• PA-02-125: Bioengineering Nanotechnology Initiative (supercedes PA-00-018)
  (expires on June 3, 2005)
• PA-02-108: Structural Biology of Membrane Proteins SBIR/STTR Announcement
  (expires on April 10, 2005)
• PA-02-103: Research on Ethical Issues in Human Studies
  (expires in April 2005)
• PAR-02-097: Innovation Grants for Research on Hutchinson-Gilford Progeria Syndrome
  (expires on April 1, 2005)
• PA-02-072: Methodology and Measurement in the Behavioral and Social Sciences
  (expires on March 10, 2005)
• PAR-02-069: Career Enhancement Award for Stem Cell Research
  (expires on June 1, 2005)
• PA-02-044: Animal Models of Organ-specific Tolerance for Heart and Lung Transplantation
  (expires March 1, 2005)
• PA-02-043: Social and Cultural Dimensions of Health
  (expires on December 21, 2004)
• PA-02-034: Pathophysiology and Treatment of Chronic Fatigue Syndrome (CFS)
  (expires on January 10, 2005)
• PA-02-025: Plasticity of Human Stem Cells in the Nervous System
  (expires on November 30, 2004)
• PA-02-011: Bioengineering Research Grants
  • Addendum: NOT-EB-04-003, Changes expiration from October 1, 2004 to March 1 2005
  (expires on March 1, 2005)
  
• PA-01-112: The Role of Antioxidants in the Prevention of Diabetic Complications (final receipt date for applications will be October 1, 2004)
• PA-01-086: Restless Legs Syndrome and Periodic Limb Movement Disorder
• PA-01-044: Research on Emergency Medical Services for Children
• PA-01-017: Physical Activity and Obesity Across Chronic Diseases
• PA-00-131: NIH National Research Service Awards for Senior Fellows (F33)
• PA-00-109: Self-Management Strategies Across Chronic Diseases
• PA-00-088: Earth-Based Research Relevant to the Space Environment
• PA-00-055: Hemochromatosis and Diabetes Mellitus
• PA-00-046: Biobehavioral Research for Effective Sleep
• PA 00-020: Independent Scientist Award (K02)
  NHLBI Supplemental Information to the NIH Independent Scientist Award
• PA 00-004: Mentored Patient-Oriented Research Career Development Award (K23)
• PA 00-003: Mentored Clinical Scientist Development Award (K08)
  • NHLBI Supplemental Information to the NIH Mentored Clinical Scientist Development Award (11/18/99)
  • Revised Supplemental Information (1/29/03)
  
  
• PA 99-159: The Role of Growth Factors in the Development of Diabetes Complications
• PAR 99-154: Career Transition Award (K22)
• PA 99-117: Protein Structure Initiative (Structural Genomics) -- SBIR/STTR
• PA 99-085: Bone and the Hematopoietic and Immune Systems
• PA 99-084: SBIR/STTR Study and Control of Microbial Biofilms
• PA 99-079: Research on Ethical Issues in Human Studies
• PA 99-075: Beryllium-Induced Diseases
• PA 99-062: Academic Research Enhancement Award
• PA 99-048: Technologies to Improve the Utility of Animal Models
• PA 99-035: Impact of Aging on Development of Atrial Fibrillation
• PA 99-016: Mechanisms Underlying Individual Variations in Drug Responses
• PAS 99-010: Bioengineering Research Partnerships
• PAR 99-009: Bioengineering Research Grants
  
  
• PA 98-088: Research on the Hematologic Abnormalities in AIDS
• PA 98-078: Genetic Architecture of Complex Phenotypes
• PA 98-074: The Zebrafish as an Animal Model for Development and Disease Research
• PA 98-070: Research on Microbial Biofilms
• PAS 98-060: Developmental Processes in Differential Expression of Globin Genes
• PA 98-052: Mentored Patient-Oriented Research Career Development Award
• PA 98-046: Diet and Cardiovascular Disease Risk in Children and Adolescents
• PA 98-031: Methodology and Measurement in the Behavioral and Social Sciences
• PA 98-014: Thrombopoietin, Megakaryocytopoiesis and Platelet Production
  
  
• PA 97-111: Respiratory Pathogens: Specific Research Needs
• PA 97-092: Gene Therapy in Aging
• PA 97-089: Mechanisms of the Immune Response to Xenotransplant Antigens
• PA 97-085: The Latent State in Tuberculosis Infection
• PA 97-084: Innovative Approaches to Investigating Human Tuberculosis
• PA 97-083: Tuberculosis - Basic Biology, Immunology and Pathogenesis
• PA 97-064: Institutional National Research Service Award in Sleep Research
• PA 97-022: Cellular and Molecular Mechanisms of Primary Pulmonary Hypertension
• PA Unnumbered: Development of New Gene Therapy Vectors and Delivery Systems (SBIR/STTR)
  
  
• PA 96-066: Research on the Hematologic Abnormalities in AIDS
• PA 96-011: Cellular and Molecular Mechanisms of Lymphangioleiomyomatosis