Health Information for Patients
A Service of The U.S. Department of Health and Human Services |
"Side Effects of Anti-HIV Medications" |
September 2004 Fact Sheets - Health Information for Patients P.O. Box 6303, Rockville, MD 20849-6303 |
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Hepatotoxicity
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Hyperglycemia
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Hyperlipidemia
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Lactic Acidosis
Terms Used in This Fact Sheet |
Liver function tests (LFTs): tests that measure the blood levels of liver enzymes (proteins made and used by the liver) to determine if your liver is working properly. |
Mitochondrial toxicity: also referred to as mitochondrial dysfunction. Damage to the mitochondria that can cause problems in the heart, nerves, muscles, pancreas, kidneys, and liver. It may also cause changes in the blood, such as thrombocytopenia (too few platelets), anemia (too few red blood cells), and neutropenia (too few neutrophils). Mitochondrial damage can lead to lactic acidosis and hepatic steatosis (fatty liver) and may also play a role in lipodystrophy (see Lipodystrophy Fact Sheet). |
Nucleoside reverse transcriptase inhibitor (NRTI): class of anti-HIV medication. NRTIs are faulty versions of the building blocks (nucleosides) used by reverse transcriptase, a protein that HIV needs to make copies of itself. The NRTIs approved by the FDA are Combivir, Emtriva, Epivir, Epzicom, Hivid, Retrovir, Trizivir, Truvada, Videx, Viread, Zerit, and Ziagen. |
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Lipodystrophy
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Osteonecrosis, Osteopenia, and Osteoporosis
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Skin Rash
This information is based on the U.S. Department of Health and Human Services' Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents (available at http://aidsinfo.nih.gov).