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National Center for Complementary and
Alternative Medicine (NCCAM)
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Active Funding Announcements (PAs, RFAs, RFPs)


NCCAM is currently accepting applications in response to the following initiatives.

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Active Program Announcements (PAs)

  • Pathogenesis and Treatment of Lymphedema and Lymphatic Diseases
    PA-04-071
    Release Date: 03/05/04
    Expiration Date: 12/31/06
    The purpose of this program announcement is to stimulate research on the biology of the lymphatic system, to characterize at the molecular, cellular, tissue, organ, and intact organism levels, the pathophysiologic mechanisms that cause the disease, to develop new methods for quantitating and imaging lymph flow, to discover new therapeutic interventions, and to determine the safety, efficacy and mechanisms of action of complementary and alternative therapies.

  • CAM Practitioner Research Education Project Grant Partnership
    PAR-04-097
    Release Date: 04/21/04
    Expiration Date: 09/16/06
    The goal of this program announcement is to increase the quality and quantity of the research content in the curricula at complementary and alternative medicine (CAM) institutions in the United States where CAM practitioners are trained.

  • General Clinical Research Center Complementary and Alternative Medicine Research Program
    PAR-04-087
    Release Date: 04/06/04
    Expiration Date: 05/07
    The purpose of this PAR is to encourage preliminary studies of complementary and alternative medicine at the eighty General Clinical Research Centers (GCRC's) supported by the NIH National Center for Research Resources nationwide. NCCAM expects these studies to provide a foundation for larger clinical studies. In addition, this initiative is expected to expand the evaluation of CAM treatments for the wide array of diseases and conditions currently being evaluated at GCRC’s.

  • Developmental Projects in Complementary Approaches to Cancer Care
    PA-04-053
    Release Date: 02/02/04
    Expiration Date: 10/05, unless reissued
    NIH invites research grant applications from interested investigators to conduct innovative developmental pilot research investigating complementary approaches in cancer. The intent of this initiative is to encourage and support the development of basic and clinical complementary cancer research and to provide the basis for more extended research projects.

  • Clinical Cancer Therapy and Prevention Research
    PA-04-046 (see addendum NOT-AT-04-004)
    Release Date: 12/24/03
    Expiration Date: 11/02/05, unless reissued
    NCCAM is interested in applications to support research on efficacy and correlated clinical or other markers for complementary and alternative therapies including, but not limited to, the use of botanicals and other natural products, alternative dietary approaches, complementary uses of acupuncture, and energy and manipulative therapies.

  • Diet Composition and Energy Balance
    PA-04-033
    Release Date: 12/10/03
    Expiration Date: 11/06
    The goal of this program announcement is to invite research applications investigating the role of diet composition in energy balance, including studies in both animals and humans. Both short and longer-term studies would be encouraged, ranging from basic studies investigating the impact of micro- or macronutrient composition on appetite, metabolism, and energy expenditure through clinical studies evaluating the efficacy of diets differing in micro- or macronutrient composition, absorption, dietary variety, or energy density for weight loss or weight maintenance.

  • NIH Clinical Trial Planning Grant (R34) Program
    PA-04-008
    Release Date: 10/16/03
    Expiration Date: 11/15/06
    The purpose of this planning grant is to provide support for the development of a Phase III clinical trial, including the establishment of the research team, the development of tools for data management and oversight of the research, the definition of recruitment strategies, and the finalization of the protocol and other essential elements of the study included in a manual of operations/procedures. This planning grant is not designed for the collection of preliminary data or the conduct of pilot studies to support the rationale for a clinical trial.

  • NCCAM Exploratory/Developmental Grant for Clinical Studies (R21)
    PAR-03-153
    Release Date: 7/17/03
    Expiration Date: 7/06
    NCCAM invites high quality exploratory/developmental clinical research grant applications, in all domains of complementary and alternative medicine, in order to provide preliminary data that can be used as a foundation for larger clinical studies.

  • Biobehavioral Pain Research
    PA-03-152
    Release Date: 7/11/03
    Expiration Date: 7/30/06
    The purpose of this program announcement is to inform the scientific community of the interests of the various institutes at NIH and to stimulate and foster a wide range of basic and clinical studies on pain as they relate to the missions of these Institutes.

  • Secondary Analysis of Data on CAM Use in Minority Populations
    PAR-03-102
    Application Receipt Dates: 8/15/03; 8/16/04; 8/16/05
    Expiration Date: 4/06
    The NCCAM invites applications for research grants to support secondary analyses of existing data sets regarding CAM use in racial and ethnic minority populations.
  • NCCAM International Postdoctoral Fellowship
    PA-03-050
    Application Receipt Dates: 04/05/03; 12/05/03; 12/05/04; 12/05/05
    Expiration Date: 12/06/05
    The NCCAM International Postdoctoral Fellowship supports training of foreign researchers in rigorous scientific methodology at a clinical or basic research facility in the United States.

  • Developmental Centers for Research on Complementary and Alternative Medicine (DCRC)
    PAR-03-046
    Letter of Intent Receipt Date: 03/15/03; 01/17/04; 01/15/05
    Receipt Date: 04/15/03; 02/17/04; 02/15/05
    Developmental Centers will support U19 cooperative agreements in which CAM and conventional institutions and investigators will partner to conduct exploratory and developmental research projects. These awards will provide opportunities for CAM institutions and investigators to strengthen their research expertise and infrastructure while enabling conventional researchers to gain clinical and cultural perspectives critical to the conduct of CAM research.
  • Centers of Excellence for Research on Complementary and Alternative Medicine
    PAS-03-038
    Letter of Intent Receipt Dates: 03/29/03, 01/16/04, 01/15/05
    Receipt Dates: 04/29/03, 02/17/04, 02/15/05
    Centers of Excellence will support program project grants (P01) to elucidate the mechanisms of action of CAM modalities. These awards will provide new opportunities for experienced molecular or cellular biologists, imaging scientists, immunologists, neurobiologists, pharmacologists, physiologists, and other scientists to investigate fundamental questions related to CAM.


  • Basic and Preclinical Research on Complementary and Alternative Medicine (CAM)
    PA-02-124
    Release Date: 07/02/02
    Expiration Date: 07/15/05, unless reissued
    NIH invites research grant applications to stimulate basic, mechanistic, and preclinical research across the broad spectrum of biomedical science underlying CAM practices. This research will strengthen the biomedical research knowledge bases needed to inform CAM clinical practice.

  • Research on Ethical Issues in Human Studies
    PA-02-103
    Release Date: 05/01/02
    Expiration Date: 04/05, unless reissued
    The purpose of this program announcement is to support research addressing the ethical challenges of involving human participants in research in order to inform and optimize protections for human participation in research.

  • Ancillary Studies on Control Groups in Clinical Trials
    PA-02-094
    Release Date: 04/03/02
    The purpose of this PA is to fund ancillary studies that will address the biological, behavioral, and statistical issues related to the control or comparison group and the effects of inclusion of a placebo group on clinical trial design.

  • Methodology and Measurement in the Behavioral and Social Sciences
    PA-02-072
    Release Date: 03/07/02
    NIH invites applications on methodology and measurement in the behavioral and social sciences. Methodology and measurement issues include the processes that underlie research design, data collection techniques, measurement, and data analysis techniques in the social and behavioral sciences.

  • Social and Cultural Dimensions of Health
    PA-02-043
    Release Date: 12/21/01
    The goal of this announcement is to encourage further development of health-related social sciences research relevant to the missions of the NIH Institutes and Centers.

  • Pathophysiology and Treatment of Chronic Fatigue Syndrome
    PA-02-034
    Release Date: 12/11/01
    The purpose of this PA is to invite investigator-initiated research grant applications to support research on the pathophysiology and treatment of chronic fatigue syndrome (CFS) in diverse groups and across the life span.

  • Chromium as Adjuvant Therapy for Type 2 Diabetes and Impaired Glucose Tolerance
    PA-01-114
    Release Date: 07/02/01
    The NIH invites basic and clinical applications to study the role of chromium as adjuvant therapy in type 2 diabetes and/or impaired glucose tolerance.

  • Quick-Trials for Novel Cancer Therapies
    PA-00-047
    Release Date: 1/27/00
    QUICK-TRIAL will provide a new approach designed to simplify the grant application process and provide a rapid turnaround from application to funding. Features include a modular grant application and award process, inclusion of the clinical protocol within the grant application, and accelerated peer review with the goal of issuing new awards within 5 months of application receipt.

  • Academic Research Enhancement Award
    PA-99-062
    Release Date: 02/11/99
    The National Institutes of Health (NIH) is continuing to make a special effort to stimulate research in educational institutions that provide baccalaureate training for a significant number of the Nation's research scientists but that have not been major recipients of NIH support.

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Active Requests for Applications (RFAs)

  • The Use of Complementary and Alternative Medicine (CAM) in the Management of HIV/AIDS
    RFA: AT-05-004
    Letter of Intent Receipt Date: 12/14/04
    Receipt Date: 01/14/05

    The objectives of this solicitation are to (1) identify potential roles for CAM therapies in managing HIV/AIDS and/or its complications; (2) understand mechanisms of action of CAM interventions that have the potential for contributing to or interfering with standard treatments for HIV/AIDS and related conditions; and (3) stimulate CAM research at leading HIV/AIDS research institutions.

  • Prevention and Treatment of Childhood Obesity in Primary Care Settings
    RFA: HD-04-020
    Letter of Intent Receipt Date: 10/25/04
    Receipt Date: 11/23/04
    Research projects would test intervention programs delivered in primary care practices to improve dietary and physical activity behaviors of pediatric patients.

  • NIH Roadmap Initiatives
    Several grants and funding opportunities have been developed through the NIH Roadmap Initiatives.

  • Ancillary Studies to Obesity-Related Clinical Trials
    RFA: DK-03-022
    Letter of Intent Receipt Date: 2/19/04, 10/19/04, 6/17/05
    Receipt Date: 3/19/04, 11/19/04, 7/19/05
    The goal of this initiative is to solicit research grant applications for ancillary studies investigating obesity-related research questions in conjunction with six cooperative agreement clinical trials and consortia sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and one cooperative agreement sponsored by the National Insitute on Aging (NIA). These ancillary study proposals may utilize patients and/or patient materials from the seven clinical cooperative agreements cited in the RFA, subject to study-specific restrictions. The NCCAM is interested in supporting investigations of complementary or alternative approaches to weight maintenance and the prevention and treatment of overweight or obesity.

  • Clinical Research Curriculum Award
    RFA: HL-04-004
    Letter of Intent Receipt Date: 12/16/03
    Receipt Date: 1/16/04
    NIH invites educational and research institutions to apply for this program, which addresses, in part, the NIH's commitment to improve the quality of training in clinical research. The initial and competing renewal awards will be for five years each.

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Active Requests for Proposals (RFPs)

There are no active Requests for Proposals at this time.

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Related Topics
bullet Expired Funding Announcements (PAs, RFAs, RFPs)
bullet Notices Related to Funding
bullet NIH Guide for Grants and Contracts - for all published RFPs, RFAs, and PAs.
bullet The NCCAM Training page lists all active training and career development announcements.

 
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