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shRNA Info
Purchase shRNA Clones
Related Links
Quick Links:
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RNA Interference
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Human
Release 1.5
(8/17/04) |
Mouse
Release 2.4
(9/10/04) |
| shRNA clones (total) |
14104 |
4696 |
| UniGene targets |
5304 |
1786 |
| Pseudogene targets |
68 |
0 |
| Other targets |
5250 |
1616 |
| Average number shRNA clones/target |
1.3 |
1.4 |
About RNAi on CGAP
The NCI is part of the consortium supporting the preparation of human and mouse
libraries containing RNAi constructs that target cancer-relevant and other genes.
The clones produce small RNA molecules, called shRNA (short hairpin RNA), that are available
to the public from a
commercial distributor.
The first shRNA clone release appeared on March 25, 2004 and was in the pSHAG-MAGIC vector.
Recent modifications have generated an improved pSHAG-MAGIC2c vector and, therefore,
the entire first set of clones has been replaced. This second release will contain targets
to the original gene set and additional new genes. However, the RNAi targets may be different
from those in the first release due to the introduction of a new and improved algorithm.
We hope to have the complete collection available by December 2004.
| More info? |
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For background information about the shRNA project, please read
shRNA Background. |
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For information about the design rationale behind the shRNA construct,
please see shRNA Construct. |
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For technical information about the library methods and vector used in library construction,
please read Library Methods and
shRNA Vector Map. |
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For references relating to RNAi, please see
References. |
RNAi Gene Searcher - Find Genes Containing RNAi Constructs
Genes with Clones containing RNAi Constructs
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