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CHEMOPREVENTIVE AGENT DEVELOPMENT RESEARCH GROUP

Funding Opportunities

Announcement of Request for Proposals (RFP): N01-CN-25026-76 Preclinical In Vitro and In Vivo Screening Assays for Cancer Preventive Agent Development

The Division of Cancer Prevention (DCP), National Cancer Institute (NCI) is seeking proposals from qualified organizations who have the ability to screen potential cancer preventive agents in a variety of in vitro and short-term in vivo assays and to establish the infrastructures composed of one or more collaborating institutions that will conduct these screening assays. The assays will assess the potential of various agents to inhibit, reverse, or delay the early process of carcinogenesis by evaluating the biologic effects of these agents on a variety of endpoints, such as for example, on specific molecular targets; on processes involved in the development and maintenance of carcinogenesis, e.g., transformation, proliferation, and apoptosis; and on validating new assays and techniques, such as quantitative image analysis. For the in vivo tests a required endpoint shall be the histopathologic evaluation of cancers. Application due date is November 13, 2002.

See the following website: http://rcb.nci.nih.gov under Current Requests for Proposals

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