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Biology Research Projects
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- Developmental biology (from conception to adulthood) and the biology of aging.
- Normal functioning of genes, including their identification and expression, and the normal function of gene products, such as hormones and growth factors.
- Normal formation of the extracellular matrix.
- Normal cell to cell interactions.
- More...
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- Abnormal chromosome number.
- Aberration in chromosomes and genes (e.g., in chronic myelogenous leukemia).
- Damage to chromosomes and mutation in genes.
- Failures in DNA repair.
- Aberrant gene expression.
- Epigenetics.
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- Genes and signals involved in growth stimulation or repression, including oncogenes (Ras, etc.), and tumor suppressor genes (p53, etc.) and hormones and growth factors such as estrogens, androgens, TGF-beta, GM-CSF, etc.
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- Latency, promotion, and regression.
- Expansion of malignant cells.
- Interaction of malignant cells with the immune system or extracellular matrix.
- Cell detachment.
- Cell motility.
- Invasion.
- Penetration of the vascular system.
- Malignant cells in the circulation.
- Extravasation and growth of metastases.
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- (Note: grants coded as 1.2 in previous versions of the CSO become 1.5)
- Informatics and informatics networks.
- Specimen resources.
- Epidemiological resources pertaining to biology.
- Reagents, chemical standards.
- Education and training of investigators.
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- (Historical Code; for internal use only by CSO Partners. For crosswalk purposes previous 1.1 codes become 1.6)
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