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About CSR

What Happens to Your Grant Application
A Primer for New Applicants

The Center for Scientific Review (CSR) receives all NIH and many other Public Health Service grant applications. Most investigator-initiated applications for NIH funds are referred to CSR review groups. The NIH Institutes and Centers (ICs) coordinate the review of many IC-specific applications and use the same peer review process described below.

Your application is assigned to a review group and an NIH Institute or Center

One or more CSR Referral Officers examines your application and determines the most appropriate Integrated Review Group (IRG) to assess it for scientific merit. Your application is then assigned to one of the IRG’s study sections. A study section typically includes 20 or more scientists from the community of productive researches. Your application also will be assigned to the NIH IC best suited to fund your application should it have sufficient merit. (More than one IC may be assigned if appropriate.) 

Referral Officers follow established guidelines that define the review boundaries of each study section. These boundaries frequently overlap, and more than one study section may have the expertise to review your application. You may request in a cover letter with your application that it be assigned to a particular study section or IC. The CSR referral office seriously considers such requests.

The combined expertise of the scientists in a study section is intended to span the breadth and diversity of the science it covers. CSR may recruit temporary reviewers or secure mail reviews from outside consultants. Special Emphasis Panels also may be formed on an ad-hoc basis to review applications when special expertise is required or when special circumstances arise.

An assignment notice is sent to you
Within 10 days of determining your assignments, CSR will send notices to you and your sponsored research office. You may question either your study section or IC assignment by contacting the Scientific Review Administrator (SRA) noted in your letter or the CSR referral office (301-435-0715). It usually takes 6 weeks to refer the 16,000 applications submitted each round. If you do not receive your notice within this period, you should contact the referral office.

Reviewers are identified
Your SRA will analyze the content of your application, check for completeness, and decide which study section members can best review it or act as discussants. Unless a conflict of interest exists, all study section members receive copies of your application approximately 6 weeks before their meeting. Typically, two or three members are asked to provide written reviews of each application, and one or two additional members serve as discussants. 

Because of the multi-month period between submission and review, applicants often wish to submit additional materials. Before you do, you should contact your SRA to ascertain the acceptable content, format, and deadline. 

Before the study section meets, members list all R01 applications believed to be in the lower half for scientific merit. If all members agree, these applications are “streamlined.” The will not be discussed at the meeting, but the assigned reviewers will still provide written critiques. “Streamlining” is not equivalent to disapproval.

Review Meeting
The review meeting is convened
Study section members convene for about 2 days. One member serves as chair and conducts the meeting with the SRA. Relevant NIH extramural staff are encouraged to attend, but they may not participate. Assigned reviewers and discussants present their evaluations and outside opinions are read. After a general discussion, members mark their priority scores privately on scoring sheets, which are later tabulated by CSR.

The results are sent to you
Within a few days after the meeting, a computer-generated letter with your priority score and percentile ranking is automatically mailed to you. In about 6 weeks, your summary statement will be delivered to the assigned IC, which will send you a copy. It will include (1) the written critiques produced by the assigned reviewers, (2) the SRA’s summary of the study section’s discussion, (3) study section recommendations, and (4) administrative notes of special consideration.

The assigned NIH Institute or Center Takes Charge
After the review, an IC program officer will be your main point of contact. He or she may help interpret your review results or answer questions about the further consideration of your application. In a second level of peer review, IC Advisory Councils may consider the study section’s recommendations and determine the relevance of your proposed research to IC priorities and public health needs. 

Get More Information on Peer Review at CSR

CSR Policy, Procedure & Review Guidelines Web Page  

CSR Best Practices Web Page

Get General Grant Information

The NIH Office of Extramural Research Grants (OER) Web page provides a wealth of information on funding opportunities, grant application forms, instructions, and policies. It also operates the NIH GrantsInfo service, which can be contacted via e-mail (grantsinfo@nih.gov) or phone (301 435-0714). In addition, the OER Web site provides information on the peer review policies and procedures pertaining to all NIH components that conduct peer reviews.

 

Last Update: November 12, 2003
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