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Antiretroviral Drugs

Fusion Inhibitors
  Enfuvirtide (Fuzeon, T-20)

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
  Delavirdine (Rescriptor)
  Efavirenz (Sustiva)
  Nevirapine (Viramune)

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  Abacavir (Ziagen)
  Abacavir + Lamivudine (Epzicom)
  Abacavir+Lamivudine+Zidovudine (Trizivir)
  Didanosine (Videx, ddI)
  Emtricitabine (Emtriva, FTC)
  Emtricitabine + Tenofovir DF (Truvada)
  Lamivudine (Epivir, 3TC)
  Lamivudine+Zidovudine (Combivir)
  Stavudine (Zerit, d4T)
  Tenofovir DF (Viread)
  Zalcitabine (Hivid, ddC)
  Zidovudine (Retrovir, AZT, ZDV)

Protease Inhibitors (PIs)
  Amprenavir (Agenerase)
  Atazanavir (Reyataz)
  Fosamprenavir (Lexiva, 908)
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  Lopinavir+Ritonavir (Kaletra)
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  Ritonavir (Norvir)
  Saquinavir (Fortovase, Invirase)
Home > Drugs > Zerit, d4T
Stavudine (Zerit, d4T)

   Generic Name: Stavudine
    Brand Name: Zerit, d4T

Stavudine, also known as Zerit or d4T, is a type of antiretroviral drug called a nucleoside reverse transcriptase inhibitor (NRTI). This class of drugs blocks reverse transcriptase, an enzyme (cell protein that helps chemical reactions) that HIV needs to make more copies of itself.

AIDSinfo Drug Record for Stavudine



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Guidelines References to Stavudine

Adult and Adolescent Guidelines
Table 12a: Antiretroviral Regimens Recommended for Treatment of HIV-1 Infection in Antiretroviral Naïve Patients
Table 12b: Advantages and Disadvantages of Antiretroviral Components Recommended as Initial Antiretroviral Therapy
Table 13: Antiretroviral Dosing Recommendations for Patients with Renal or Hepatic Dysfunction
Table 14: Antiretroviral Regimens or Components That Should Not Be Offered At Any Time
Table 15: Characteristics of Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Table 19: Adverse Drug Reactions and Related "Black Box Warnings" in Product Labeling for Antiretroviral Agents
Table 21: Drug Interactions Between Antiretrovirals and Other Drugs: PIs, NNRTIs, and NRTIs
Table 23: HIV-Related Drugs with Overlapping Toxicities
Table 30: Preclinical and Clinical Data Concerning the Use of Antiretrovirals During Pregnancy

Pediatric Guidelines
Appendix: Characteristics of Available Antiretroviral Drugs
NRTI Drugs - Pediatrics
Supplement: Pediatric Antiretroviral Drug Information
Table 11: Recommended Antiretroviral Regimens for Initial Therapy for HIV Infection in Children
Table 8: Advantages and Disadvantages of NRTI, NtRTI Combinations for Use in Highly Active Antiretroviral Combination Regimens

Perinatal Guidelines
NRTI Drugs - Perinatal
Table 2: Preclinical and Clinical Data Relevant to the Use of Antiretrovirals During Pregnancy
Table 3: Antiretroviral Drug Use in Pregnant HIV-Infected Women: Pharmacokinetic and Toxicity Data in Human Pregnancy and Recommendations for Use in Pregnancy

Stavudine News

Labeling Changes for Stavudine (Zerit, d4T), January, 2002

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More About Stavudine

AIDSinfo Drug Record for Stavudine

MEDLINEplus Fact Sheet on Stavudine

Clinical Trials Using Stavudine

Literature Citations for Stavudine

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Related Web Site Links

Join the FDA HIV/AIDS E-mail List Serv

National Library of Medicine AIDS Portal

Database for Anti-HIV Compounds

NLM - Specialized Information Services AIDSDRUGS Structures

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