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Antiretroviral Drugs

Fusion Inhibitors
  Enfuvirtide (Fuzeon, T-20)

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
  Delavirdine (Rescriptor)
  Efavirenz (Sustiva)
  Nevirapine (Viramune)

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  Abacavir (Ziagen)
  Abacavir + Lamivudine (Epzicom)
  Abacavir+Lamivudine+Zidovudine (Trizivir)
  Didanosine (Videx, ddI)
  Emtricitabine (Emtriva, FTC)
  Emtricitabine + Tenofovir DF (Truvada)
  Lamivudine (Epivir, 3TC)
  Lamivudine+Zidovudine (Combivir)
  Stavudine (Zerit, d4T)
  Tenofovir DF (Viread)
  Zalcitabine (Hivid, ddC)
  Zidovudine (Retrovir, AZT, ZDV)

Protease Inhibitors (PIs)
  Amprenavir (Agenerase)
  Atazanavir (Reyataz)
  Fosamprenavir (Lexiva, 908)
  Indinavir (Crixivan)
  Lopinavir+Ritonavir (Kaletra)
  Nelfinavir (Viracept)
  Ritonavir (Norvir)
  Saquinavir (Fortovase, Invirase)
Home > Drugs > Combivir
Lamivudine+Zidovudine (Combivir)

   Generic Name: Lamivudine+Zidovudine
    Brand Name: Combivir

Lamivudine/zidovudine, also known as Combivir, is a combination of the two anti-HIV medicines, lamivudine (Epivir) and zidovudine (Retrovir). Both medicines belong to the class of antiretroviral drugs called nucleoside reverse transcriptase inhibitors (NRTIs). This class of drugs blocks reverse transcriptase, an enzyme (cell protein that helps chemical reactions) that HIV needs to make more copies of itself.

AIDSinfo Drug Record for Lamivudine+Zidovudine



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Guidelines References to Lamivudine+Zidovudine

Adult and Adolescent Guidelines
Table 12a: Antiretroviral Regimens Recommended for Treatment of HIV-1 Infection in Antiretroviral Naïve Patients
Table 12b: Advantages and Disadvantages of Antiretroviral Components Recommended as Initial Antiretroviral Therapy
Table 14: Antiretroviral Regimens or Components That Should Not Be Offered At Any Time
Table 15: Characteristics of Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Table 19: Adverse Drug Reactions and Related "Black Box Warnings" in Product Labeling for Antiretroviral Agents
Table 23: HIV-Related Drugs with Overlapping Toxicities
Table 30: Preclinical and Clinical Data Concerning the Use of Antiretrovirals During Pregnancy

Pediatric Guidelines
Appendix: Characteristics of Available Antiretroviral Drugs
NRTI Drugs - Pediatrics
Supplement: Pediatric Antiretroviral Drug Information
Table 11: Recommended Antiretroviral Regimens for Initial Therapy for HIV Infection in Children
Table 8: Advantages and Disadvantages of NRTI, NtRTI Combinations for Use in Highly Active Antiretroviral Combination Regimens

Perinatal Guidelines
NRTI Drugs - Perinatal
Table 2: Preclinical and Clinical Data Relevant to the Use of Antiretrovirals During Pregnancy
Table 3: Antiretroviral Drug Use in Pregnant HIV-Infected Women: Pharmacokinetic and Toxicity Data in Human Pregnancy and Recommendations for Use in Pregnancy
Table 5: Comparison of Intrapartum/Postpartum Regimens for HIV-1-Infected Women in Labor Who Have Had No Prior Antiretroviral Therapy (Scenario #3)

Lamivudine+Zidovudine News


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More About Lamivudine+Zidovudine

AIDSinfo Drug Record for Combivir

MEDLINEplus Fact Sheet on Combivir

Clinical Trials Using Combivir

Literature Citations for Combivir

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Related Web Site Links

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National Library of Medicine AIDS Portal

Database for Anti-HIV Compounds

NLM - Specialized Information Services AIDSDRUGS Structures

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