Requests for Applications

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• Notices
• Active Requests for Applications
• Past Requests for Applications

Notices

• 07/14/03
  Plans to develop an RFA to continue the NIH Botanical Research Centers Program.

Active Requests for Applications

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Past Requests for Applications

• Research on Mind-Body Interactions and Health
  RFA: OD-03-008
  Letter of Intent Receipt Date: 11/17/03
  Receipt Date: 12/17/03
  The NIH invites applications in support of research on mind-body interactions and health. "Mind-body interactions and health" refers to the relationships among cognitions, emotions, personality, social relationships, and health.
  
  
• Dietary Supplement Research Centers: Botanicals
  RFA: OD-04-002
  Letter of Intent Receipt Date: 5/18/04
  Receipt Date: 6/15/04
  The goal of this initiative is to support research centers of excellence which will (1) promote interdisciplinary collaborative study of botanicals, particularly those that are found as ingredients in dietary supplements and (2) conduct research of high potential for being translated into practical benefits for human health.
  
  
  • An Applicant Information Meeting was held on February 6, 2004.
    
    
• Mind-body Interactions and Health: Exploratory/Developmental Research Program (R21)
  RFA: OB-03-005
  Letter of Intent Receipt Date: 06/16/03
  Receipt Date: 07/16/03
  The National Institutes of Health (NIH) invite applications for infrastructure grants in support of research on mind-body interactions and health. "Mind-body interactions and health" refers to the relationships among cognitions, emotions, personality, social relationships, and health. Exploratory/Developmental Awards are intended to support the development and demonstrate the feasibility of programs at institutions that have high potential for advancing mind-body and health research, but have not yet fully achieved the necessary resources and mechanisms to qualify for a R24 Research Infrastructure Award.
  
  
• Mind-body Interactions and Health: Research Infrastructure Program (R24)
  RFA: OB-03-004
  Letter of Intent Receipt Date: 06/16/03
  Receipt Date: 07/16/03
  The National Institutes of Health (NIH) invite applications for infrastructure grants in support of research on mind-body interactions and health. "Mind-body interactions and health" refers to the relationships among cognitions, emotions, personality, social relationships, and health.
  
  
• Cranberry: Urinary Tract Infection and Other Conditions
  RFA: AT-03-004
  Letter of Intent Receipt Date: 04/22/03
  Receipt Date: 05/20/03
  The purpose of this initiative is to support basic and clinical research on the role of cranberry (Vaccinium macrocarpon) in the prevention and treatment of urinary tract infections (UTI), other infections, and other conditions for which there is credible evidence of efficacy.
  
  
• Planning Grants for International Centers for Research on Complementary and Alternative Medicine (PICRC)
  RFA: AT-03-002
  Letter of Intent Receipt Date: 02/28/03
  Receipt Date: 03/28/03
  Planning Grants for International Centers will support U.S. and international institutions to jointly plan exploratory and developmental studies of traditional/alternative healing approaches. The Planning Grants will lay the groundwork for developing applications for an International Center for Research on CAM that will be called for in 2004.
  
  
• Complementary and Alternative Medicine (CAM) Therapy in the Treatment of HIV/AIDS
  RFA: AT-03-001
  Letter of Intent Receipt Date: 11/11/02
  Receipt Date: 12/10/02
  This initiative will support research to identify potential roles for the safe and effective use of CAM in the treatment of HIV/AIDS and its complications, or to ameliorate medication side effects. NCCAM and the National Institute of Nursing Research (NINR) are especially interested in supporting well-designed studies to characterize and investigate traditional medicine practices used in the treatment of HIV/AIDS.
  
  
• Human Subjects Research Enhancements Programs
  RFA: OD-02-003
  Letter of Intent Receipt Date: 03/05/02
  Receipt Date: 05/15/02
  The purpose of this initiative is to provide short-term interim support for institutional activities that will strengthen oversight of human subjects research at institutions that receive significant NIH support for clinical research.
  
  
• S-Adenosyl-L-Methionine (SAMe) and Liver Disease
  RFA: AA-02-011
  Letter of Intent Receipt Date: 04/15/02
  Receipt Date: 05/15/02
  The purpose of this RFA is to invite applications for grants proposing innovative basic and preclinical research to understand how SAMe may be effective in the treatment of liver disease caused by alcohol and other factors such as hepatitis C virus (HCV).
  
  
• Alternative Therapies for Benign Prostate Symptoms--Clinical Trials Consortium
  RFA: DK-02-026
  Letter of Intent Receipt Date: 03/15/02
  Receipt Date: 04/15/02
  The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Center for Complementary and Alternative Medicine (NCCAM), and the Office of Dietary Supplements (ODS) invite cooperative agreement grant applications to establish a research consortium to conduct a randomized controlled clinical trial of Serenoa repens (Saw palmetto) and Pygeum africanum in men with benign prostatic hyperplasia (BPH).
  
  
• Announcement to Manufacturers of Saw Palmetto Product
  
  
• Bioterrorism-Related Research
  RFA: NOT-AI-02-003
  Letter of Intent Receipt Date: 01/15/02
  Receipt Date: 02/15/02
  NCCAM is interested in applications for innovative research targeted at testing complementary and alternative medicine therapeutic or preventive agents for pathogens that might conceivably be vehicles for biological warfare activities.
  
  
• Botanical/Drug Interactions in HIV
  RFA: AT-02-003
  Letter of Intent Receipt Date: 02/28/02
  Receipt Date: 03/28/02
  This initiative will support research into interactions between botanical substances and prescription drugs used in the treatment of human immunodeficiency virus (HIV) infection and its complications.
  
  
• Elucidation of the Underlying Mechanisms of Placebo Effect
  RFA: AT-02-002
  Letter of Intent Receipt Date: 03/01/00
  Receipt Date: 04/11/02
  The goal of this initiative is to stimulate integrative research aimed at delineating the underlying mechanisms by which a placebo leads to its ultimate physiological and psychological effects.
  
  
  • 5 grant applications received funding.
  
  
  
• The Placebo Effect in Clinical Practice
  RFA: AT-02-001
  Letter of Intent Receipt Date: 03/01/02
  Receipt Date: 04/11/02
  The proposed initiative is expected to stimulate investigator-initiated research investigations on how placebos and placebo effects impact on clinical practice. An important goal is to understand what factors are necessary to elicit a placebo effect in clinical practice so that the benefits of the therapeutic intervention can be enhanced to improve health and promote wellness.
  
  
  • 7 grant applications received funding.
  
  
  
• EDTA Chelation Therapy for Coronary Artery Disease
  RFA: AT-01-004
  Letter of Intent Receipt Date: 07/18/01
  Receipt Date: 08/29/01
  The purpose of this RFA is to invite applications for a multi-site, randomized, double-blinded, placebo-controlled trial investigating the efficacy and safety of EDTA (ethylene diamine tetra-acetic acid) chelation therapy in individuals suffering from Coronary Artery Disease (CAD).
  
  
• NCCAM Institutional Research Training Program (T32) for Minority Researchers
  RFA: AT-01-003
  Letter of Intent Receipt Date: 04/16/01
  Receipt Date: 05/14/01
  This Ruth L. Kirschstein National Research Service Award (NRSA) RFA will fund research training at minority and minority-serving institutions for individuals who are training for careers in biomedical, behavioral, and clinical research related to complementary and alternative medicine (CAM).
  
  
• Complementary/Alternative Medicine (CAM) at the End of Life for Cancer and/or HIV/AIDS
  RFA: AT-01-002
  Letter of Intent Receipt Date: 02/26/01
  Receipt Date: 04/12/01
  The primary objective of this initiative is to identify and evaluate CAM interventions for patients with advanced, terminal disease associated with cancer or HIV/AIDS. This research is expected to generate scientific knowledge on complementary and alternative medicine (CAM) therapies that will ultimately lead to improved care and quality of life for individuals at the end of life.
  
  Possible patient outcomes would include:
  1. Managing or reducing the symptoms associated with the conditions of end stage disease for cancer and HIV/AIDS;
  2. Preventing or reducing side effects of medications such as antiretrovirals, steroids, and chemotherapy/radiotherapy; and
  3. Enhancing the psychological, social, spiritual well-being, and quality of life at the end of life.
  
  
• Integration of Complementary and Alternative Medicine: A Health Services Research Perspective
  RFA: AT-01-001
  Letter of Intent Receipt Date: 12/08/00
  Receipt Date: 01/24/01
  The intent of this RFA is to 1) identify barriers and facilitators to the integration of CAM and conventional health care practices; 2) determine whether CAM research results obtained from studies conducted under ideal conditions (efficacy studies) can be translated to real-world settings (i.e., effectiveness) within an integrated model; and 3) support the evaluation of currently planned or recently initiated programs, goals of which are to improve the outcomes, quality, effectiveness, and/or cost-effectiveness of health care through the integration of CAM and conventional health care.
  
  
• Botanical Drug Interactions
  RFA: AT-00-004
  Letter of Intent Receipt Date: 11/10/00
  Receipt Date: 01/12/01
  The main objective of this initiative is to encourage biomedical research in order to prevent adverse botanical/drug interactions during therapy or anesthesia, to establish possible synergistic combinations of botanicals with pharmaceutical drugs, and to increase our knowledge of the mechanisms of action of botanicals.
  
  
• Exploratory Program Grants for Frontier Medicine Research
  RFA: AT-00-002
  Letter of Intent Receipt Date: 08/07/00
  Receipt Date: 11/14/00
  This NCCAM initiative will establish Exploratory Program Grants for Frontier Medicine Research, the purpose of which will be to create an infrastructure to nurture and therefore advance this field of biomedical research by providing the institutional support and resources necessary for rigorous scientific investigation.
  
  
• Botanical Products Development: SBIR and STTR
  RFA: AT-00-003
  Letter of Intent Receipt Date: 09/07/00
  Receipt Date: 11/14/00
  The purpose of this Request for Applications (RFA) is to support projects that could lead to development of appropriate standardized products (valerian root, feverfew, echinacea, and milk thistle) and provision of a reliable constant supply of these products for clinical research, as well as basic research.
  
  
• Global Network for Women's and Children's Health Research
  RFA: HD-00-007
  Letter of Intent Receipt Date: 04/14/00
  Receipt Date: 07/13/00
  The purpose of this solicitation is to establish an innovative and flexible research network that will be responsive to the most critical existing and emerging health needs and public health problems of women and children, globally.
  
  
• Centers for Dietary Supplement Research: Botanicals
  RFA: OD-00-004
  Letter of Intent Receipt Date: 03/25/00
  Receipt Date: 04/25/00
  The Office of Dietary Supplements (ODS) and the NCCAM invite grant proposals to establish Specialized Research Centers to investigate the biological effects of botanicals including, but not limited to, botanicals available as dietary supplements. The creation of such Centers is needed to advance the quality and quantity of scientific information on botanicals and to promote further research in this area.
  
  
• Centers for Complementary and Alternative Medicine Research
  RFA: AT-00-001
  Letter of Intent Receipt Date: 01/07/00
  Receipt Date: 03/14/00
  The National Center for Complementary and Alternative Medicine (NCCAM), the National Cancer Institute (NCI), and the National Heart, Lung, and Blood Institute (NHLBI) invite applications for Centers for CAM Research using the P50 Specialized Center grant mechanism. Such Centers will provide the resources necessary for the rigorous scientific investigation of CAM. It is expected that research conducted at these Centers will examine the potential efficacy, effectiveness, safety, and validity of CAM practices, as well as the physiological or psychological mechanisms underlying or contributing to the effects of these practices. Applicants should propose a multidiscliplinary research focus that incorporates basic and clinical research with either an asthma or cancer theme.
  
  
• Ginkgo Biloba Prevention Trial in Older Individuals
  RFA: AT-99-001
  Letter of Intent Receipt Date: 04/21/99
  Receipt Date: 05/21/99
  The National Center for Complementary and Alternative Medicine (NCCAM) and the National Institute on Aging (NIA) invite applications for a two-arm, double-blind, randomized, placebo-controlled multi-site trial to assess whether an extract of the botanical product, Ginkgo biloba, prevents the occurrence of dementia and/or cognitive decline in older individuals.
  
  
• Research on Care at the End of Life
  RFA: NR-99-004
  Letter of Intent Receipt Date: 04/30/99
  Receipt Date: 05/21/99
  The purpose of this initiative is to generate research that will improve the quality of dying for Americans and decrease the distress for their caregivers. Research applications may include basic, clinical, or health care studies focused on the clinical management of physical and psychological symptoms, patient-provider and patient-family communication, ethics and clinical decision-making, caregiver support, or the context of care delivery for those facing life-limiting illnesses.
  
  
• Centers for Complementary and Alternative Medicine Research
  RFA: OD-98-008
  Letter of Intent Receipt Date: 12/11/98
  Receipt Date: 01/22/99
  Applications are being sought for Centers for CAM Research using the Specialized Center (P50) grant mechanism. Such Centers will provide resources necessary for the rigorous scientific investigation of CAM. It is expected that research conducted at these Centers will examine the efficacy, effectiveness, safety, and validity of CAM practices, as well as the physiological or psychological mechanisms underlying these practices.
  
  
• Specialized Centers of Research (SCORS) in Ischemic Heart Disease in Blacks
  RFA: HL-98-015
  Letter of Intent Receipt Date: 05/07/99
  Receipt Date: 09/15/99
  Interdisciplinary study of issues surrounding the expression of heart disease in Blacks. Applicants should select one of the following three themes: Sudden Cardiac Death; Microvascular Disease; Diabetic Heart Disease.
  
  
• Specialized Centers of Research in Ischemic Heart Disease
  RFA: HL-98-007
  Letter of Intent Receipt Date: 06/12/98
  Receipt Date: 12/29/98
  Interdisciplinary approaches to the elucidation of the etiology and pathophysiology of ischemic heart disease, sudden cardiac death, and heart failure at the molecular, cellular, and tissue levels.
  
  
• Basic and Clinical Research on Fibromyalgia
  RFA: AR-98-006
  Letter of Intent Receipt Date: 05/15/98
  Receipt Date: 07/15/98
  Research studies related to all aspects of pathogenesis and clinical manifestations of fibromyalgia syndrome (FMS) and to relationships between FMS and temporomandibular disorders (TMDs).
  
  
• Innovative Approaches to Disease Prevention Through
  Behavior Change
  RFA: OD-98-002
  Letter of Intent Receipt Date: 04/01/98
  Receipt Date: 05/21/98
  A four-year research grant program to test interventions designed to achieve long-term health behavior change.
  
  
• Centers for Complementary and Alternative Medicine Research
  RFA: OD-98-003 ERRATA
  Letter of Intent Receipt Date: N/A
  Receipt Date: 01/13/98
  A correction issued for RFA OD-98-003, which was published in the NIH GUIDE, Volume 26, Number 34, October 10, 1997.
  
  
• Centers for Complementary and Alternative Medicine Research
  RFA: OD-98-003
  Letter of Intent Receipt Date: 12/01/97
  Receipt Date: 01/13/98
  The OAM, NICHD, and NIDA seek to encourage research of CAM by establishing CAM Centers of Research, which will make the resources necessary for the conduct of high quality research available to investigators interested in CAM.
  
  
• Acupuncture Treatment for Osteoarthritis
  RFA: OD-97-006
  Letter of Intent Receipt Date: 08/17/97
  Receipt Date: 09/19/97
  The OAM and NIAMS seek to initiate a clinical trial of acupuncture for the treatment of osteoarthritis (OA) of the knee. See correction or ERRATA issued on August 1, 1997.
  
  
• Center for Chiropractic Research
  RFA: OD-97-005
  Letter of Intent Receipt Date: 04/09/97
  Receipt Date: 05/09/97
  Seeks to encourage research of chiropractic by establishing a Center for Chiropractic Research, which will make the resources necessary for the conduct of high quality research available to investigators interested in chiropractic.
  
  

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This page last modified September 21, 2004

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