NIAMS IRP Labs & Branches
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Molecular Immunology and Inflammation Branch Chief, Molecular Immunology and Inflammation Branch
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
The MIIB conducts basic and clinical investigations on the molecular mechanisms underlying immune and inflammatory responses in rheumatic and autoimmune diseases. A major focus of the Branch is the study of receptor-mediated signal transduction and how these events link to the regulation of genes involved in inflammatory responses. The Branch comprises two sections:
Lymphocyte Cell Biology Section - Chief, John J. O'Shea Conducts research into the molecular basis of cytokine action to define the mechanisms by which these mediators regulate processes such as development, differentiation, memory, tolerance and homeostasis in immune cells. The section also studies patients with primary immunodeficiency and autoinflammatory syndromes. Molecular Inflammation Section - Chief, Juan Rivera Conducts research on the molecular mechanisms of the inflammatory response and how immune receptors contribute to inflammation and disease. The section seeks new targets and strategies to control inflammatory rheumatic diseases. For more detailed information on these two sections, please visit the following web pages: |
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