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Understanding Clinical TrialsIntroduction to Clinical Trials Cancer Clinical Trial Web SitesBethesda Trials: Cancer.gov: CAM Cancer Treatment TrialsPhase I Study of Gemcitabine and Mistletoe in Patients With Advanced Solid Tumors Shark Cartilage in Treating Patients With Advanced Colorectal or Breast Cancer Shark Cartilage Extract in Treating Patients With Metastatic Kidney Cancer: This is a randomized phase III trial to determine the effectiveness of shark cartilage extract in treating patients who have metastatic kidney cancer that has not responded to biological therapy. A trial for non-small cell lung cancer patients comparing conventional chemotherapy + radiation therapy with shark cartilage. This trial is being performed at several centers across the U.S. and Canada and is coordinated by the MD Anderson Cancer Center in Houston, Texas. Evaluation of Intensive Pancreatic Proteolytic Enzyme Therapy with Ancillary Nutritional Support in the Treatment of Inoperable Pancreatic Adenocarcinoma. A trial at Columbia University for patients with advanced pancreatic cancer with a nutritional regimen with oral pancreatic enzymes and a detoxification regimen (the Kelley/Gonzalez regimen). Prostate Cancer Lifestyle Trial (diet, exercise, stress management): This study is the first randomized study on how intensive changes in diet and lifestyle may change the progression of biopsy on Prostate Cancer. Memorial Sloan-Kettering Cancer Center trial of diet and prostate cancer. A randomized study of the effect of a diet low in fat and high in soy, fruits, vegetables, green tea, vitamin E, and fiber on PSA levels in patients with prostate cancer. Epidemiologic, Prevention and Symptom Management StudiesUse of Complementary or Alternative Medicine Practices by Women at Increased Risk for Breast Cancer: The purpose of this study is to find out how prevalent complementary or alternative medicine (CAM) practices are among women at increased risk of breast cancer, what practices are used, and why women are using them. CAM practices are medical approaches not generally recognized as standard medical treatments. They may include, for example, use of dietary supplements, mega-dose vitamins, herbal preparations, meditation, spiritual healing, visualization, and massage therapy, among others. Macrobiotic Diet and Flax Seed: Effects on Estrogens, Phytoestrogens, & Fibrinolytic Factors:This study will investigate, in a randomized, three-arm study, the effects of two interventions that are high in phytoestrogens on various parameters related to estrogen metabolism and fibrinolysis. Approximately 120 women will be randomized to receive an American Heart Association (AHA) Step 1 diet, an AHA Step 2 diet + 10 g/day flax seed, or a macrobiotic dietary intervention. Blood and urine samples will be drawn at baseline, and at three, six, nine, and twelve months, to examine both short and long-term effects of these interventions. Outcomes include blood and urine levels of total estrogens and estradiol, and related metabolites; antigens to plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (t-PA), fibrin D-dimer, and von Willebrand Factor; and endothelial function as measured by high-resolution ultrasound. Blood levels of antioxidant vitamins and retinoids will also be examined. Omega-3-Fatty Acids for Cancer Cachexia: Phase I/II (CALGB-9473) Survey of the Use of Alternative Medical Therapies in Adult Cancer Patients Enrolled in Phase I Clinical Trials: This is a survey and interview study of phase I cancer patients enrolled in ongoing clinical trials at the National Cancer Institute to determine the prevalence of alternative therapy use in this population. This study will also examine patient attitudes and perceptions regarding their use of alternative therapy as compared with their scientifically-sanctioned phase I experimental therapy. This information has important implications for drug development. Clinical Trials ArchiveThis is a listing of CAM cancer trials that have been closed to accrual. |
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