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Drugs, chemicals and biologicals

Repository: Chemical Reagents
Repository: Biological Reagents
Drug Development Programs
Database: Proteins
Database: Carcinogens
Database: Anti-Cancer Compounds
Preclinical Development of Drugs and Biologics

Repository: Chemical Reagents

Angiogenesis Resource Center

Reference reagents, endothelial cells, evaluations of test agents

Chemical Carcinogen Reference Standards Repository

Carcinogens, chemopreventive agents, chemical biomarkers, standards

Natural Products Repository

More than 50,000 plant samples; more than 10,000 marine invertebrates and algae samples

Pure Chemicals Repository

Library of 140,000 synthetic and pure natural compounds for developing new agents to treat cancer

Radiolabeled Compounds Repository

Radiolabeled products and drugs, 2D and 3D structure

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Repository: Biological Reagents

Biological Products Laboratory Repository- HIV reagents

Monoclonal antibodies, kits, and reagents for use in AIDS vaccine research

Biological Resources Branch (BRB) Preclinical Repository

Monoclonal antibodies, bulk cytokines, human and murine cytokine standards

Mammalian Phosphorylation Resource (MPR)

Information on commercially available phospho-specific antibodies.

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Drug Development Programs

Rapid Access to Intervention Development (RAID)-Drug Development

Resources for preclinical development of drugs and biologics; in vivo screens

Rapid Access to Prevention Intervention Development (RAPID)

Resources for preclinical development and Phase I studies of chemopreventive agents

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Database: Proteins

Databases From the Laboratory of Experimental and Computational Biology

Database of proteins, protein disease, 2D protein gel images

Protein Reviews on the Web (PROW) Database

Structured reviews and categorized information on proteins and their orthologs

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Database: Carcinogens

Chemical Carcinogenesis Research Information System (CCRIS)

Information and databases on more than 8,000 carcinogens, mutagens

Monographs on the Evaluation of Carcinogenic Risks to Humans

Reviews on carcinogenicity and mutagenicity of chemical agents

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Database: Anti-Cancer Compounds

Chemical Structure Database of Anti-Cancer Screened Compounds.

Structures and screening results for compounds tested in anti-cancer screens

Database of NCI Yeast Anti-Cancer Drug Screen Results

Results of more than 97,000 compounds screened against yeast panel strains

Database of NCI's 60 Cell Line Anti-cancer Drug Screen Results

Drug sensitivity of more than 70,000 compounds

Enhanced NCI Database Browser

Search over 250,000 compounds; improved output features and substructure search capabilities

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Preclinical Development of Drugs and Biologics

NIH Inter-Institute Program for the Development of AIDS-Related Therapeutics (IIP)

Pre-clinical therapy development assistance for AIDS-related indications

Rapid Access to NCI Discovery Resources (R-A-N-D)

Resources for the discovery and early pre-clinical development of anti-cancer agents

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