Laboratory of Biochemistry
Boon Chock, PhD, Chief
This laboratory's research program includes: 1) studies on the
role of oxygen free radical mediated oxidation of enzymes in aging
and various diseases (especially those involved in pulmonary dysfunction
and atherosclerosis); 2) detailed characterization of several bacterial
selenoproteins, the mechanism of biosynthesis of biosynthesis of
selenophosphate and 2-selenouridine including EPR studies; 3) studies
on the regulation of protein ubiquitinating proteins, formation
and utilization of free radicals, and cytosolic calcium oscillation;
4) biochemical studies of the HIV-1 protease, which is essential
for virus replication.
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Department of
Health and Human Services
National
Institutes of Health
National Heart, Lung, and
Blood Institute
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