- Internet Grateful
Med
Internet Grateful Med (IGM) is a World Wide Web application running on
a gateway system at the U.S. National Library of Medicine (NLM). When you
first see it, Internet Grateful Med is set to search in MEDLINE - more than
nine million citations to the biomedical literature of the world, from 1966
to the present. IGM provides assisted searching in MEDLINE (including PREMEDLINE)
and 14 other databases: AIDSLINE, AIDSDRUGS, AIDSTRIALS, DIRLINE, HealthSTAR,
HSRPROJ, HISTLINE, OLDMEDLINE, SDILINE, SPACELINE, BIOETHICSLINE, POPLINE,
TOXLINE and CHEMID.
A brief description of each database is available from the IGM introductory
screen. The system helps you create and refine a search, then submits the
search to PubMed or Elhill, NLM's retrieval engines. Internet Grateful Med
was released searching MEDLINE in Elhill in April, 1996. The new IGM V2.6
released in September, 1998 searches MEDLINE (including PREMEDLINE) in PubMed.
It takes advantage of some very useful PubMed features such as the ability
to Find Related Articles and to link to the full text of participating journals.
- Hazardous
Substances Data Bank
The HSDB is a factual, non-bibliographic data bank focusing upon the toxicology
of potentially hazardous chemicals. It is enhanced with data from such related
areas as emergency handling procedures, environmental fate, human exposure,
detection methods, and regulatory requirements. Data are derived from a
core set of standard texts and monographs, government documents, technical
reports and the primary journal literature. The HSDB contains complete references
for all data sources utilized.
The HSDB is fully peer reviewed by the Scientific Review Panel (SRP), a
committee of experts drawn from the major subject disciplines within the
data bank's scope. The HSDB is organized by individual chemical records,
with over 4500 chemical records contained in the file. The file is being
built, maintained, reviewed, and updated on the National Library of Medicine's
(NLM) Toxicology Data Network™ (TOXNET) system, and has been supported,
in part, by the Agency for Toxic Substances and Disease Registry (ATSDR).
HSDB contains approximately 150 data fields arranged in eleven broad subject
categories, plus a category for administrative information. These categories
are structured as follows:
- Administrative Information
- Manufacturing/Use Information
- Safety and Handling
- Pharmacology
- Exposure Standards and Regulations
- Additional References
- Substance Identification
- Chemical and physical Properties
- Toxicity/Biomedical Effects
- Environmental/Fate/Exposure Potential
- Monitoring and Analysis Methods
- Express Update
- TOXNET - TOXicology
Data NETwork
TOXNET (TOXicology Data NETwork) is a computerized system of files oriented
to toxicology and related areas. It is managed by the National Library of
Medicine's (NLM) Toxicology and Environmental Health Information Program
(TEHIP) and runs on Sun servers in a UNIX-based environment. TOXNET provides
a free Web-based interface that permits easy searching of the following
files:
- HSDB™ (Hazardous Substances Data Bank)
- IRIS (Integrated Risk Information System)
- CCRIS (Chemical Carcinogenesis Research Information System)
- GENE-TOX (Genetic Toxicology)
- TRI (Toxic Chemical Release Inventory) Files
Wildlife
Toxicity Reference Values (TRVs) for Ecological Risk Assessments
The Wildlife Toxicity Assessment Program, part of the US Army Center for
Health Promotion and Preventive Medicine, has developed, and is implementing,
a standard method for developing toxicological profiles and toxicity reference
values (TRV) for military-related substances that may potentially pose risks
to wildlife. The program has written a standard practice for the development
and documentation of wildlife TRVs and is implementing this Standard Practice
for environmental chemicals of military concern. The Standard Practice is
primarily intended for use by this Center to generate wildlife TRVs that
are defensible and to provide a standard set of information for practitioners
in the field. If a TRV relevant to a particular Army ERA has been generated
by the Center using this methodology, then its use is expected unless an
alternative can be reasonably defended. The Center is implementing this
program in a phased approach, focusing upon the highest priority chemicals
first. Wildife Toxicity Assessment Reports are currently available for 2,4,6-Trinitrotoluene
(TNT), Nitroglycerine (NG), 1,3,5-Trinitrobenzene (TNB), Dinitrobenzene
(DNB), 2-amino-4,6- and 4-amino-2,6- Dinitrotoluene (aminoDNTs), HMX, and
PETN.
California
Wildlife Exposure Factor and Toxicity Database (California EPA)
The California Wildlife Exposure Factor and Toxicity Database (Cal/Ecotox)
is a compilation of exposure factors (i.e., ecological and physiological
data) and toxicity data for a number of California mammals, birds, amphibians
and reptiles. The database has been created by the Office of Environmental
Health Hazard Assessment, in collaboration with the University of California
at Davis, to provide an information resource for risk assessors conducting
ecological risk assessments in California. Cal/Ecotox is searchable by species
or chemical. In addition, complete species reports are available for downloading.
- DAIN
Metadatabase of Internet Resources for Environmental Chemicals at the University
of Kassel
This resource is designed to help you finding relevant databases for environmental
chemicals worldwide. You can search our database by name or by subject.
The subject search provides several structured search formats.
- ECDIN - Environmental
Chemicals Data and Information Network
ECDIN is a factual user-friendly data-bank which can be accessed directly
by users through either CD-ROM or via Internet (the last version of the
CD-ROM has been released during 1993). At present, the INTERNET information
of ECDIN/PHATOX can be accessed starting from the chemical substance and
finding the data (direct search). Earliest in 1998 it is foreseen to implement
the retrieval with the search by key-words.
The data contained in ECDIN/PHATOX are extracted from original published
literature of from existing databanks, with the collaboration of international
expert for the evaluation and the validation of the information before its
storage. The users of ECDIN/PHATOX have expressed interest and have recommended
that the Data Center will be expanded in order to incorporate some operational
modules which will help them in their specific field of activity. The priority
listing of the new modules as identified by end users is:
- ECDIN/PHATOX as a focal point for Antipoisoning Control Centers.
- Education and training modules.
- SAR/QSAR Models for Drug Design.
Environmental
Contaminants Encyclopedia
The Environmental
Contaminants Encyclopedia is a summary/compilation of information of importance
to general environmental toxicology rather than human toxicology. Some human
information was also summarized when it was easy to do so or seemed important
to general understanding. This product differs from existing databases in
that it has an environmental toxicology emphasis and it summarizes information
on these issues into a single, easily searchable source. Tools such as this
one are needed because at the same time there is an "information explosion"
going on, many environmental specialists are too busy to keep up with the
literature.
This website offers easily accessible information organized alphabetically
by chemical name. Contaminants specialists, environmental toxicologists,
hazardous waste specialists, environmental risk assessors, natural resource
damage assessors, contaminants researchers, land managers, spill responders,
water quality specialists, and natural resource managers, are all among
intended users.
The
Environmental Residue-Effects Database (ERED)
The U.S. Army Corps of Engineers/U.S. Environmental
Protection Agency Environmental Residue-Effects Database (ERED) is a compilation
of data, taken from the literature, where biological effects (e.g.,
reduced survival, growth, etc.) and tissue contaminant concentrations were
simultaneously measured in the same organism. Currently, the database is
limited to those instances where biological effects observed in an organism
are linked to a specific contaminant within its tissues.
- The
Herptox Page
Mainatained by the Canada Centre for Inland Waters, this web site is the
source for information pertaining to the effects of environmental contaminants
on reptiles and amphibians.
-
International Toxicity
Estimates for Risk (ITER) Database
ITER is a database of human health risk values and supporting information.
This is a test version of a new ITER database expanded to118 chemical files,
with information from U.S. Environmental Protection Agency (EPA), Agency
for Toxic Substances and Disease Registry (ATSDR) and Health Canada. Improvements
to ITER include direct links to EPA's IRIS and to ATSDR's MRL page from
each chemical file, and the ability to print reports. The data are presented
in a comparative fashion, allowing the user to view what conclusions each
organization has reached. A brief explanation of differences continues to
be provided. Information from the World Health Organization and the RIVM
(The Netherlands) will be included in the near future.
- Toxic
Chemicals in Coastal Environments
NOAA's Coastal Protection and Restoration Division (CPRD) provdies sediment
chemistry, sediment toxicity, and tissue chemistry data from specific watershed
projects.
- Toxic Release Inventory Fact Sheets
This page contains links to EPA factsheets for every regulated toxic chemical.
Presented by Open Data Solutions, Inc., of Alexandria, VA.
his
listing (in no particular order) of toxicological information resources on the
Internet is presented as a service to the United States Navy environmental community
by the Marine Environmental Support Office (see administrative
information). The information provided herein was correct, to the best of
our knowledge, at the time of publication. It is important to remember, however,
the dynamic nature of the Internet. Resources that are free and publicly available
one day may require a fee or restrict access the next, and the location of items
may change as menus and homepages are reorganized. Inclusion of any resource
in this listing does not constitute an endorsement by the United States Navy.
All descriptions are taken from the resource sites themselves, and the Marine
Environmental Support Office assumes no responsibility for their accuracy or
the contents of the sites.
Agency
for Toxic Substances and Disease Registry 
Environmental
Protection Agency
Geological
Survey
National
Institutes of Health
