Synthesizes and distributes novel or otherwise difficult-to-obtain psychoactive compounds to the scientific community for use in research relevant to mental health.
Provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters. In addition, a database offers thousands of affinity constants for ligand binding to over 125 receptors.
Provides toxicology and safety assessment of novel ligands for PET, SPECT, and fMRI in humans and limited assessment of novel psychoactive agents for clinical research and as potential therapeutic agents for the treatment of mental disorders. The goal of this program is to assess the toxicology and safety of promising, target-selective compounds for use in human studies. Toxicology and safety data generated from this program will be used by investigators in support of an Investigation New Drug (IND) application or for Radioactive Drug Research Committee (RDRC) evaluation of the compound for human studies.
The NIMH Human Genetics Initiative has funded a national Center for Genetic Studies to store, and distribute clinical data and biomaterials (DNA samples and cell lines) to aid qualified researchers in identifying genes that produce vulnerability to mental disorders that include Alzheimer's Disease, autism, bipolar disorder and schizophrenia. Further information is available at http://nimhgenetics.org/.
Public domain image processing and analysis programs are available here.
Your one-stop shopping for material transfer, cooperative research & development agreements, and licensing opportunities.
|