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NIDA Research Report



Prescription Drugs: Abuse and Addiction

From the Director

Most people who take prescription medications take them responsibly; however, the nonmedical use or abuse of prescription drugs remains a serious public health concern. Certain prescription drugs - opioids, central nervous system (CNS) depressants, and stimulants - when abused, can alter the brain's activity and lead to dependence and possibly addiction.

An estimated 9 million people aged 12 and older used prescription drugs for nonmedical reasons in 1999; more than a quarter of that number reported using prescription drugs nonmedically for the first time in the previous year. We would like to reverse this trend by increasing awareness and promoting additional research on this topic.

The National Institute on Drug Abuse (NIDA) has developed this publication to answer questions about the consequences of abusing commonly prescribed medications. In addition to offering information on what research has taught us about how certain medications affect the brain and body, this publication also discusses treatment options.

This publication was developed to help health care providers discuss the consequences of prescription drug abuse with their patients. According to a recent national survey of primary care physicians and patients regarding substance abuse, 46.6 percent of physicians find it difficult to discuss prescription drug abuse with their patients.

Prescription drug abuse is not a new problem, but one that deserves renewed attention. We hope this scientific report is useful to the public, particularly to individuals working with the elderly, who because of the number of medications they may take for various medical conditions, may be more vulnerable to misuse or abuse of prescribed medications.

Alan I. Leshner, Ph.D.
Director
National Institute on Drug Abuse

 


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This report is also available in PDF format, Prescription Drugs: Abuse and Addiction, [PDF format, 227 KB]

This report is also available in Spanish, Medicamentos de Prescripción: Abuso y Adicción

All materials appearing in the Research Reports Series are in the public domain and may be reproduced without permission from NIDA. Citation of the source is appreciated.

To obtain printed copies of this report, please call or write the National Clearinghouse on Alcohol and Drug Information, P.O. Box 2345, Rockville, MD 20852, 1-800-729-6686. NIDA Research Report - Prescription Drugs: Abuse and Addiction: NIH Publication No. 01-4881. 599801since 4/9/01


Index

Letter from the Director

What are some of the commonly abused prescription drugs?

Opioids


CNS depressants

Stimulants


Trends in prescription drug abuse

Preventing and detecting prescription drug abuse

Treating prescription drug addiction

Some Commonly Prescribed Medications: Use and Consequences

Glossary and References

 

Prescription Drugs: Abuse and Addiction Research Report Cover


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The National Institute on Drug Abuse (NIDA) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services. Questions? See our Contact Information. Last updated on Monday, October 21, 2002.