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# Title  Sort Principal Investigator  Sort State    Sort Institution  Sort Fund Mech,  Sort Project ID  Sort 1. Mechanism of Action of Folate Antagonists Bertino, Joseph R NJ Univ of Med/Dent NJ-R W Johnson MED Sch R01, CA008010 2. Centromere Structure and Function Carbon, John A CA University of California Santa Barbara R01, CA011034 3. Pharmacology of Cyclophosphamide and Other Alkylators Colvin, Oliver M NC Duke University R01, CA016783 4. Plant Antitumor Agents Lee, Kuo-Hsiung NC University of North Carolina Chapel Hill R01, CA017625 5. Cytotoxic Nitrogen Heterocycles Vedejs, Edwin MI University of Michigan at Ann Arbor R01, CA017918 6. Antiestrogens: Mechanism of Antagonist Action Katzenellenbogen, Benita S IL University of Illinois Urbana-Champaign R01, CA018119 7. Polynuclear Anticancer Antibiotics--Selected Syntheses Hauser, Frank NY State University of New York at Albany R01, CA018141 8. Applications of Natural Products to Chemical Biology Clardy, Jon C. MA Harvard University (Medical School) R01, CA024487 9. Theoretical Studies of Drug/Nucleic Acid Interactions Kollman, Peter CA University of California San Francisco R01, CA025644 10. Rational Drug Design Based on Chemical Mechanisms Coward, James K MI University of Michigan at Ann Arbor R01, CA028097 11. Role of the Acetyltransferase P300 in Cellular Responses Avantaggiati, Maria L DC George Washington University R01, CA030716 12. Photodynamic Therapy Plus Antiangiogenic Therapy Gomer, Charles J. CA Children's Hospital Los Angeles R01, CA031230 13. Synthetic Studies on Tumor Promoters and Inhibitors Wender, Paul A CA Stanford University R01, CA031841 14. Synthetic Studies Related to Cancer Research/Treatment Wender, Paul A CA Stanford University R01, CA031845 15. Ultrasound Hyperthermia System for Cancer Therapy Roemer, Robert UT University of Utah R01, CA033922 16. Nucleoside and Nucleotide Metabolizing Enzymes Mitchell, Beverly S NC University of North Carolina Chapel Hill R01, CA034085 17. Natural Product Synthesis via Electron Deficient Imines Weinreb, Steven M. PA Pennsylvania State University-Univ Park R01, CA034303 18. Synthesis and Evaluation of Novel Phosphoramidates Borch, Richard F IN Purdue University West Lafayette R01, CA034619 19. Specificity of Intercalation Reactions Chaires, Jonathan B MS University of Mississippi Medical Center R01, CA035635 20. Therapeutic Modulation of Breast Cancer Oncogenes Benz, Christopher C CA Buck Institute for Age Research R01, CA036773 21. Role of Mitochondria and Glycolysis in Tumor Cell MDR Lampidis, Theodore J FL University of Miami-Medical R01, CA037109 22. Specific Immunotherapy with Monoclonal Antibodies Bast, Robert C TX University of Texas MD Anderson Can Ctr R01, CA039930 23. New Synthetic Methods for Anticancer Research Liebeskind, Lanny GA Emory University R01, CA040157 24. Genotoxicity of Antineoplastic DNA-Cleaving Agents Povirk, Lawrence VA Virginia Commonwealth University R01, CA040615 25. Crystallographic Studies of Thymidylate Synthase Finer-Moore, Janet S. CA University of California San Francisco R01, CA041323

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