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Pronounciation of 
substitution

defined:

Replacement of one nucleotide in a DNA sequence by another nucleotide or replacement of one amino acid in a protein by another amino acid.

explained:

Listen to a detailed explanation.

Dr. Leslie Biesecker, of the National Human Genome Research Institute's Laboratory of Genetic Disease Research, defines substitution.

illustrated:

View illustration

related
terms:

amino acids, inherited, mutation, nucleotide, protein



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