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defined:
A protective gene that normally limits the growth of tumors. When a tumor supressor is mutated, it may fail to keep a cancer from growing. BRCA1 and p53 are well-known tumor suppressor genes.
explained:
Listen to a detailed explanation. Dr. Lawrence Brody, of the National Human Genome Research Institute's Genetic and Molecular Biology Branch, defines tumor suppressor gene.
relatedterms:
BRCA1/BRCA2, cancer, gene, oncogene, p53
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