Biography

Dr. Hauptmann received a Ph.D. in statistics from the University of Dortmund, Germany, in 1999. In the same year, he joined NCI as a postdoctoral fellow, and became a tenure-track investigator in 2004.

Research Interests:

• Statistical methods for assessing the effects of timing of exposure
• Methods for epidemiologic studies with missing information in exposure histories
• Polymorphisms in DNA repair genes and susceptibility to cancer of the lung and the breast
• Risk of cancer and other diseases from exposure to ionizing radiation
• Health effects of formaldehyde exposure

Keywords:
cancer, occupational epidemiology, genetic epidemiology, lung cancer, breast cancer, ionizing radiation, latency, timing of exposure, splines, case-crossover studies, missing data, DNA repair, formaldehyde

Selected Publications

• Hauptmann M, Lubin JH, Rosenberg PS, Wellmann J, Kreienbrock L. The use of sliding time windows for the exploratory analysis of temporal effects of smoking histories on lung cancer risk. Statistics in Medicine 2000; 19: 2185-2194.

·         Hauptmann M, Wellmann J, Lubin JH, Rosenberg PS, Kreienbrock L. The analysis of exposure-time-response relationships using a spline weight function. Biometrics 2000; 56: 1105-1108.

·         Hauptmann M, Berhane K, Langholz B, Lubin JH. Using splines to analyse latency in the Colorado Plateau uranium miners cohort. Journal of Epidemiology and Biostatistics 2001; 6: 417-424.

·         Hauptmann M, Pohlabeln H, Lubin JH, Jšockel KH, Ahrens W, Bršuske-Hohlfeld I, Wichmann HE. The exposure-time-response-relationship between occupational asbestos exposure and lung cancer in two German case-control studies. American Journal of Industrial Medicine 2002; 41: 89-97. (Paper awarded the 2001 National Institutes of Health Fellows Award for Research Excellence)

·         Mohan AK, Hauptmann M, Linet MS, Ron E, Lubin JH, Freedman DM, Alexander BH, Boice JD, Doody MM, Matanoski GM. Breast cancer mortality among radiologic technologists in the United States. Journal of the National Cancer Institute 2002; 94: 943-948.

·         Mohan AK, Hauptmann M, Freedman DM, Ron E, Matanoski GM, Lubin JH, Alexander BH, Boice JD, Doody MM, Linet MS. Cancer and other causes of mortality among radiologic technologists in the United States. International Journal of Cancer 2003; 103: 259-267.

·         Hauptmann M, Mohan AK, Doody MM, Linet MS, Mabuchi K. Mortality from diseases of the circulatory system in U.S. radiologic technologists. American Journal of Epidemiology 2003; 157: 239-248.

·         Travis LB, Hauptmann M, Gaul LK, Storm HH, Goldman MB, Nyberg U, Berger E, Janower ML, Hall P, Monson RR, Holm LE, Land CE, Schottenfeld D, Boice JD Jr, Andersson M. Site-specific cancer incidence and mortality after cerebral angiography with or without radioactive thorotrast. Radiation Research 2003; 160: 691-706.

·         Hauptmann M, Sigurdson AJ, Rutter JL, Chatterjee N, Hill DA, Doody MM, Struewing JP. Re: Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk (letter). Journal of the National Cancer Institute 2003; 95: 1251-1252.

·         Hauptmann M, Lubin JH, Hayes RB, Stewart P, Blair A. Mortality from lymphohematopoietic malignancies among workers employed in formaldehyde industries. Journal of the National Cancer Institute 2003; 95: 1615-1623. (Paper awarded the 2004 National Institutes of Health Fellows Award for Research Excellence)

·         Sigurdson AJ, Hauptmann M, Chatterjee N, Alexander BH, Doody MM, Rutter JL, Struewing JP. Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes. BMC Cancer 2004; 4:9.

·         Hauptmann M, Lubin JH, Hayes RB, Stewart P, Blair A. Mortality from solid cancers among industrial workers exposed to formaldehyde. American Journal of Epidemiology. 2004; 159: 1117-1130.

·         Simon SL, Weinstock RM, Doody MM, Neton J, Wenzel T, Stewart P, Mohan AK, Yoder C, Freedman M, Hauptmann M, Ron E, Bouville A, Feng A, Cardarelli J, Utterback D, Linet M. Estimating historical radiation doses to a cohort of U.S. radiologic technologists. Submitted.

·         Berhane K, Hauptmann M, Langholz B. Using tensor product splines in modeling exposure-time-response relationships: application to the Colorado Plateau uranium miners cohort. Submitted.

·         Yoshinaga S, Hauptmann M, Sigurdson AJ, Doody MM, Freedman DM, Alexander BH, Linet MS, Ron E, Mabuchi K. Non-melanoma skin cancer in U.S. radiologic technologists. Submitted.

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