NIAID : Biodefense : For Researchers : Resources : Priority Pathogens NIAID Category A, B & C Priority Pathogens

Category A Bacillus anthracis (anthrax) Clostridium botulinum Yersinia pestis Variola major (smallpox) and other pox viruses Francisella tularensis (tularemia) Viral hemorrhagic fevers Arenaviruses LCM, Junin virus, Machupo virus, Guanarito virus Lassa Fever Bunyaviruses Hantaviruses Rift Valley Fever Flaviruses Dengue Filoviruses Ebola Marburg

Category B Burkholderia pseudomallei Coxiella burnetii (Q fever) Brucella species (brucellosis) Burkholderia mallei (glanders) Ricin toxin (from Ricinus communis) Epsilon toxin of Clostridium perfringens Staphylococcus enterotoxin B Typhus fever (Rickettsia prowazekii) Food and Waterborne Pathogens Bacteria Diarrheagenic E.coli Pathogenic Vibrios Shigella species Salmonella Listeria monocytogenes Campylobacter jejuni Yersinia enterocolitica) Viruses (Caliciviruses, Hepatitis A) Protozoa Cryptosporidium parvum Cyclospora cayatanensis Giardia lamblia Entamoeba histolytica Toxoplasma Microsporidia Additional viral encephalitides West Nile Virus LaCrosse California encephalitis VEE EEE WEE Japanese Encephalitis Virus Kyasanur Forest Virus

Category C Emerging infectious disease threats such as Nipah virus and additional hantaviruses. NIAID priority areas: Tickborne hemorrhagic fever viruses Crimean-Congo Hemorrhagic fever virus Tickborne encephalitis viruses Yellow fever Multi-drug resistant TB Influenza Other Rickettsias Rabies Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) (Note: SARS-CoV added August 30, 2004)