Clinical Trials: Alzheimer's Disease and Related Disorders

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Clinical Trials: Alzheimer's Disease and Related Disorders

FEATURED STUDIES The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated with Alzheimer’s Disease. Evaluation study; outpatient. This 3-month study aims to determine whether short-term use of the medications ibuprofen and lovastatin affects levels of a protein called beta-amyloid in healthy adults who are at risk for developing Alzheimer’s Disease. Ages 18 and older. NIH Clinical Center, Bethesda, MD. Alzheimer's Disease Study. Evaluation study; inpatient and outpatient. Examines whether the medication cyclophosphamide (Cytoxan®) might help people with mild to moderate severity Alzheimer's disease. This is a 6-month study with both inpatient and outpatient visits. Ages 50-95. NIH Clinical Center, Bethesda, MD. Memory Disorder Treatment for Age-Associated Memory Impairment. Treatment study; outpatient. This study will compare the anti-inflammatory medication celecoxib (Celebrex®) to placebo in people with age-associated memory impairment. Ages 65-90. Los Angeles, CA. Memory and Cognitive Problems. Evaluation study; inpatient. Screens people with memory difficulties and tries to find the cause of the problem. This is a 3-week inpatient study, with annual 2-week inpatient visits every year thereafter. Up to age 85. NIH Clinical Center, Bethesda, MD. Additional NIH Studies Search ClinicalTrials.gov for more NIH/NIMH studies on Alzheimer's Disease and Related Disorders		Many people experience memory lapses. Some memory problems are serious, and others are not. People who have serious changes in their memory, personality, and behavior may suffer from a form of brain disease called dementia. Dementia seriously affects a person's ability to carry out daily activities. Alzheimer's disease is one of many types of dementia. ALZHEIMER'S DISEASE (AD) is an age-related and irreversible brain disorder that occurs gradually and results in memory loss, behavior and personality changes, and a decline in thinking abilities. These losses are related to the breakdown of the connections between nerve cells in the brain and the eventual death of many of these cells. About 3 percent of men and women ages 65 to 74 have AD, and nearly half of those age 85 and older may have the disease. It is important to note, however, that AD is not a normal part of aging. More information on Alzheimer's Disease and Dementia (from NIA/ADEAR)

Updated: 10/01/2004

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