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September 9, 2004 LocusLink (and Entrez Gene) expand to include Ciona intestinalis, sheep, and Takifugu rubripes. Reporting of conserved domains in RefSeqs is discontinued from LocusLink, and is reported only from Entrez Gene. More...

June 8, 2004 LocusLink (and Entrez Gene) expand to include the honey bee, Apis mellifera. GeneRIF reporting is discontinued from LocusLink, and is reported only from Entrez Gene. More...

January 29, 2004 LocusLink (and Entrez Gene) expand to include chicken, pig, and Xenopus tropicalis. These records are under development; to receive information about such releases by e-mail please consider subscribing to the Gene-announce list.

October 22, 2003 LocusLink expands to include Strongylocentrotus purpuratus and Xenopus laevis. These records are under development; to receive information about such releases by e-mail please consider subscribing to the Gene-announce list.

March-April, 2003 LocusLink begins to replace the human GO annotation supplied by the former Proteome group with that being provided by GOA . When GO annotation is available for any protein associated with a LocusID, the previous annotation is being suppressed. A comprehensive report of the GO identifiers being associated with LocusIDs is available at the LocusLink ftp site in the file loc2go.

November-December, 2002 LocusLink expands to include a new genome, namely Bos taurus. NCBI also releases The NCBI Handbook, which provides more information about LocusLink, RefSeq, and other resources, formatted either as html (click on the chapter title) or in a printable PDF format (click on the Acrobat icon).

October, 2002 A new form is available to facilitate reporting corrections or omissions to the RefSeq, LocusLink and OMIM staff.

March, 2002 MedLine Indexing Staff, who have advanced degrees in the life sciences, are now providing GeneRIF (References into Function) data [previously] shown in the Function section of the LocusLink report [and now in Entrez Gene]. If a new paper they are indexing discusses the basic biology of a gene (function, structure, genetics), they provide links between the article (PubMed ID) and the LocusLink report, and write a concise text summarizing the importance of the paper to the understanding of that gene and its products. Because of the LinkOut function, users retrieving articles in PubMed will also be able to navigate to LocusLink and Entrez Gene to learn more about the genes being referenced. MeSH indexing staff are now providing the majority of the GeneRIF records, but external scientists are still encouraged to submit independently.

1. RefSeq and LocusLink: NCBI gene-centered resources.
Pruitt KD, Maglott DR
Nucleic Acids Res 2001 Jan 1;29(1):137-140
[PubMed]   [PDF file] (reproduced with permission from NAR Online http://www.nar.oupjournals.org)

2. Introducing RefSeq and LocusLink: curated human genome resources at the NCBI.
Pruitt KD, Katz KS, Sicotte H, Maglott DR
Trends Genet. 2000 Jan;16(1):44-47.
[PubMed]